Abstract：
:Unlike the defined role of angiotensin-converting enzyme (ACE) gene in adult hypertension, ACE gene did not show direct influence on childhood blood pressure (BP), rather, seemed to be related to childhood growth with age-dependent characteristics. Thus, we examined intermediate effects of postnatal growth between the ACE polymorphisms and BP. We analyzed data from 257 children born in 2001-04 at Ewha Womans University Hospital in Seoul, Korea, and followed them up until 3 years of age. Children with excessive adiposity had higher BP, as rapid growers did to no-change and decelerated growers. The ACE II genotype was associated with greater growth acceleration than the DD genotype (II: 46.8% vs. DD: 23.9%), and with a higher BP. The interactions between ACE genotype and adiposity at age 3 were significant on the BP levels. The highest BP increase with the same degree of adiposity was observed in those with the II genotype [β (SE) for BMI: 1.9 (0.9), p=0.04]; particularly, only rapid grown II carriers demonstrated statistical significance on this linear association. These results suggested that ACE polymorphisms and BP association are mediated by postnatal growth. Further studies are required to determine the age-specific ACE genetic effects and its undefined biological mechanism.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Min J,Kim YJ,Lee H,Park EA,Cho SJ,Hong YM,Oh SY,Ha E,Kang D,Park Hdoi
10.1016/j.earlhumdev.2011.10.008subject
Has Abstractpub_date
2012-06-01 00:00:00pages
425-9issue
6eissn
0378-3782issn
1872-6232pii
S0378-3782(11)00334-3journal_volume
88pub_type
杂志文章abstract：UNLABELLED:The aim of the study was to determine the effect of a low oral dose of erythromycin on whole gastrointestinal transit time [WGTT]. Erythromycin [EM] [1.5 mg/kg, 6 hourly] or placebo was given first over 7 days in a double blind randomized crossover study of 21 preterm infants with feed intolerance. Median [r...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0378-3782(01)00191-8
更新日期：2001-12-01 00:00:00
abstract：BACKGROUND:Tyrosine hydroxylase (TH) is a specific marker for catecholaminergic neurones. Some reports have demonstrated a decrease of TH in the Sudden Infant Death Syndrome (SIDS) compared with controls. To further investigate this, the correlation between TH and sleep apnea was investigated here. MATERIALS AND METHO...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.08.007
更新日期：2003-12-01 00:00:00
abstract：AIM:To compare the order and age of emergence of rolling prone to supine and supine to prone before the introduction of back to sleep guidelines and 20 years after their introduction. METHODS:The original normative data for the Alberta Infant Motor Scale (AIMS) were collected just prior to the introduction of back to ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.10.009
更新日期：2013-05-01 00:00:00
abstract：:As major sport events have been cancelled and postponed in response to COVID-19, the necessity to protect and provide a holistic approach to the professional athlete has never been greater. To do so one must understand the negative consequences for athletes in relation to the cancellation and postponement of such even...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105254
更新日期：2020-11-12 00:00:00
abstract：INTRODUCTION:The sex ratio at birth (usually denoted as M/T=male divided by total births) is influenced by cultural factors. The Chinese Zodiac holds that women born in the Fire Horse year (1966) would be unlucky. It has been shown that significantly less children were born in Japan in this year. This study was carried...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.08.011
更新日期：2016-12-01 00:00:00
abstract：:Neonatal sepsis is frequently accompanied by significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)70008-8
更新日期：2014-03-01 00:00:00
abstract：:One hundred consecutive cranial computed tomographic scans were reviewed in children aged 0-2 years, presenting to the Royal Belfast Hospital for Sick Children. The mean age at scanning was 8.3 months and 73% of the scans were abnormal. The majority of scans were performed electively (78%). The commonest indication fo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(91)90011-q
更新日期：1991-08-01 00:00:00
abstract：:Slide show presentations have become integral to the workplace, and PowerPoint is ubiquitous since it ships with the Microsoft Office Suite. However, the increasing sophistication of such software may encourage presenters to privilege form over content. It is possible to apply scientific research from Educational Psyc...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.06.006
更新日期：2018-10-01 00:00:00
abstract：:Little is known about thrombopoietin (Tpo) production in human fetuses and neonates. As a step toward determining whether Tpo is relevant to platelet production in the fetus and neonate, we hypothesized that: (1) like other cytokines, Tpo is present in the cord blood in higher concentrations than in adult plasma; (2) ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00077-2
更新日期：1999-01-01 00:00:00
abstract：:Nurses worldwide have striven to establish nursing as a profession, autonomous but complementary to the medical profession. Literature as far back as the Renaissance demonstrates an overall derogatory attitude toward the nurse's role. The modern notion of the nurse working side by side the medical practitioner continu...
journal_title：Early human development
pub_type： 杂志文章,实务指引
doi：10.1016/j.earlhumdev.2020.105015
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Non-nutritive suck (NNS) is one piece of the complex oral feeding process, yet there is paucity on how it develops throughout the first year of life. AIMS:To determine changes in infant NNS between 3 and 12 months of age. STUDY DESIGN:Twenty-six full-term infants (65% male) completed this study. All infant...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105141
更新日期：2020-10-01 00:00:00
abstract：:No statistically significant relationships were observed between the red blood cell acid phosphatase polymorphism (ACP-1) and birth weight, duration of gestation and proportion of preterm infants in a large series of newborn infants (greater than 8000) in Cardiff. These results are contrasted with those of a similar, ...
journal_title：Early human development
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
abstract：BACKGROUND:Mothers have been shown to have higher morning cortisol on days they go to work compared to non-workdays; however, it is unknown how maternal workday associates with child morning cortisol or the attunement of mother-child morning cortisol. AIMS:This study examined the presence and stability of morning cort...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.11.007
更新日期：2014-01-01 00:00:00
abstract：:Cord blood thyroxine (T4) concentrations were measured in 4,068 infants from 28 wk gestation to term. Each chart was reviewed for the following factors: delivery by cesarean section, prolonged rupture of membranes, neonatal asphyxia, meconium-stained amniotic fluid, maternal diabetes mellitus and twinning. Each neonat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(78)90031-2
更新日期：1978-09-01 00:00:00
abstract：:The fatty acid content of fetal tissues was utilized to estimate essential fatty acid accretion during intrauterine growth. These rates of essential fatty acid accretion were used to predict that 400 mg/kg of body weight for omega-6 fatty acids and 50 mg/kg of body weight for omega-3 fatty acids per day would be used ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(81)90016-5
更新日期：1981-09-01 00:00:00
abstract：:Altogether 2159 pregnancies among black and white Americans in the Collaborative Perinatal Study and dental casts from the children at the age of 5-12 years were studied to find out the effect of maternal smoking on deciduous tooth crown growth. Minor crown size reduction (2-3%) in some dimensions was found in childre...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90086-v
更新日期：1992-08-01 00:00:00
abstract：BACKGROUND:An increased risk of major congenital abnormalities after IVF and ICSI has been described, but underlying mechanisms are unclear. This study evaluates the effects of ovarian hyperstimulation, the in vitro procedure and time to pregnancy (TTP) - as proxy for the severity of subfertility - on the prevalence of...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.06.002
更新日期：2012-10-01 00:00:00
abstract：:Improvements in perinatal and neonatal management have not only led to a higher survival rate of very low birth weight infants (VLBW; < or = 1,500 g or < 32 weeks gestational age), but also to a better outcome of these children. However the percentage of VLBW children who need special education because of later school...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00056-0
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Children born preterm are at risk for developing reading difficulties and for decrements in other cognitive skills compared to children born at term. AIMS:To assess how domains of function, often negatively impacted by preterm birth, predict reading development in children born preterm and at term. STUDY D...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.01.012
更新日期：2019-03-01 00:00:00
abstract：:The presence of dilated bowel loops antenatally suggests fetal bowel obstruction. Neonatal intestinal obstruction can have different variations in presentation depending on the level and extent of obstruction. Some of these conditions can be diagnosed antenatally. Antenatal detection of surgically correctable anomalie...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2006.02.005
更新日期：2006-05-01 00:00:00
abstract：BACKGROUND:Some researchers have developed child feeding indices to summarize child feeding practices so that they can compare child feeding practices across countries and monitor changes over time within a given country. AIMS:An adapted version of the infant and child feeding index (ICFI) developed by Ruel and Menon ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.10.009
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To assess patterns of nutritive sucking in very preterm infants ≤32 weeks of gestation. STUDY DESIGN:Very preterm infants who attained independent oral feeding were prospectively assessed with an instrumented feeding bottle that measures nutritive sucking. The primary outcome measure was nutritive sucking pe...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105044
更新日期：2020-07-01 00:00:00
abstract：:In the scholarly environment, research findings are disseminated as journal papers which support/dispute extant knowledge or add further to what is already known. The entire manuscript needs to be cited (in-text) and referenced (at the end of article), in order for readers to ascertain the validity of the research cla...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.09.012
更新日期：2019-01-01 00:00:00
abstract：:Lipids have physical, chemical, and physiological properties that make them important factors in human nutrition. They form a group of compounds of varied chemical nature that have the common property of being soluble in organic solvents but insoluble in water. This basic property affects their digestion, absorption, ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(01)00211-0
更新日期：2001-11-01 00:00:00
abstract：:The relationship between cyclic 3',5'-adenosine monophosphate (cAMP) excretion and creatinine clearance, urinary phosphate excretion, and urinary osmolarity was studied under basal conditions in 29 babies of 28-40 weeks gestation, during the first few days of life. Urinary cAMP excretion was directly related to creati...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(84)90112-9
更新日期：1984-09-01 00:00:00
abstract：:Magnetic Resonance Imaging is becoming more widely available and increasingly important for imaging the neonatal brain. In newborn infants it poses challenges regarding patient preparation, safety, optimal timing, and sequence optimization. These issues are addressed in this paper and indications for performing neonat...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2008.11.009
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the pregnancy outcome in pregnancies with threatened abortion (miscarriage). MATERIAL AND METHOD:A prospective cohort study was performed on 1000 pregnant women. 500 women (case group), had a history of vaginal bleeding during the first half of pregnancy and the other 500 women (control group), d...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.02.005
更新日期：2010-03-01 00:00:00
abstract：:The idea of an artificial neural network is introduced in a historical context, and the essential aspect of it, viz., the modifiable synapse, is compared to the aspect of plasticity in the natural nervous system. Based on such an artificial neural network, a model is presented for the way in which (the path along whic...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/0378-3782(93)90045-v
更新日期：1993-09-01 00:00:00
abstract：AIM:Depression during pregnancy is a significant cause of adverse birth outcomes, and its prevalence has increased in recent years. This study aimed to give an updated quantification of the risk of preterm birth (PTB), low birth weight (LBW) and intrauterine growth restriction (IUGR) that is associated with antenatal d...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105243
更新日期：2021-01-01 00:00:00
abstract：:In the infant, sucking behaviour is one of the first coordinated muscular activities. It is under the control of the brainstem. In utero sucking is observed from 13 weeks' gestation. The healthy full-term newborn infant has a very stable rhythm of alternating bursts of sucking with pauses in between. The non-nutritive...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(00)00091-8
更新日期：2000-11-01 00:00:00
