Abstract:
:Intra-uterine growth restriction (IUGR) is a severe and quite common problem in obstetrics. A condition of placental dysfunction can lead to a cardiovascular adaptation in the fetus characterized by a redistribution of cardiac output to maintain oxygen supply to the heart, adrenal glands and brain - the so-called brain sparing effect - at the expense of visceral organs (such as the gastrointestinal system). This condition may predispose IUGR infants to impaired gut function after birth. A higher incidence of necrotizing enterocolitis (NEC) is documented in IUGR preterm infants. Therefore, a common practice in neonatal intensive care units is to delay feeds to reduce the risk of feeding intolerance. Recent trials, however, have shown that early enteral feeding in IUGR infants is safe and it would appear, on the basis of the few available data, that breast milk could offer protection against NEC. This mini-review offers an update on feeding in IUGR infants. Future perspectives on the usefulness of Doppler and regional splanchnic and cerebral saturation monitoring for deciding when to start feeding are also provided.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Bozzetti V,Tagliabue PE,Visser GH,van Bel F,Gazzolo Ddoi
10.1016/j.earlhumdev.2013.07.006subject
Has Abstractpub_date
2013-10-01 00:00:00pages
S21-3eissn
0378-3782issn
1872-6232pii
S0378-3782(13)00153-9journal_volume
89 Suppl 2pub_type
杂志文章abstract::In 1% of monozygotic twin pregnancies, one fetus is without a heart; blood circulation is maintained by an accompanying "pump" twin. Such an acardiac condition is usually diagnosed on the basis of further malformations visible by ultrasonography. We describe a monoamniotic twin pregnancy with early growth reduction in...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(98)00011-5
更新日期:1998-08-28 00:00:00
abstract::The relationship between maternal menstrual history and small-for-gestational-age (SGA) births is examined in a population-based birth cohort of 5291 mothers with singleton births and 28 completed gestational weeks in Qingdao, China, in 1992. Multivariate analyses suggest that the length of the menstrual cycle and age...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00031-5
更新日期:1997-10-10 00:00:00
abstract:BACKGROUND:Few studies describe in detail the pregnancy and early development of infants with Prader-Willi syndrome (PWS). However, variations at these early stages may partially account for differences in the later phenotype. A recent paper described an abnormally high number of problems in pregnancy and early infancy...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2007.08.007
更新日期:2008-05-01 00:00:00
abstract::Twenty-eight very low birth weight (VLBW) and 32 full term infants were prospectively assessed at one year of age for hearing, language development and neurological status. The prevalence of conductive hearing deficits was the same in both groups. Language scores in VLBW infants were significantly lower than in fullte...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(90)90007-6
更新日期:1990-10-01 00:00:00
abstract::A new protocol for structured observation of motor performance in infants, SOMP-I, was applied to 72 neonatally healthy fullterm infants at 0, 2, 4, 6 and 10 months of age. It contains 13 items, formed as ascending scales, consisting of detailed descriptions of motor performance in different body positions and body pa...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)01598-J
更新日期:1995-01-30 00:00:00
abstract:BACKGROUND:The long-term effect of early intervention in infants at risk for developmental disorders is unclear. The VIP project (n=46, originally) evaluated by means of a randomised controlled trial the effect of the family centred early intervention programme COPCA (Coping with and Caring for infants with special nee...
journal_title:Early human development
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.earlhumdev.2017.02.002
更新日期:2017-01-01 00:00:00
abstract::Adrenocortical response to stress in neonates was assessed by estimating salivary concentrations of cortisol, dehydroepiandrosterone (DHEA) and dehydroepiandrosterone-sulfate (DHEA-S). Behavioral responses to stress were also scored clinically, according to the method of Lewis and Thomas [15]. The modulation of these ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(96)01749-5
更新日期:1996-09-20 00:00:00
abstract::Altogether 2159 pregnancies among black and white Americans in the Collaborative Perinatal Study and dental casts from the children at the age of 5-12 years were studied to find out the effect of maternal smoking on deciduous tooth crown growth. Minor crown size reduction (2-3%) in some dimensions was found in childre...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(92)90086-v
更新日期:1992-08-01 00:00:00
abstract:OBJECTIVE:To assess patterns of nutritive sucking in very preterm infants ≤32 weeks of gestation. STUDY DESIGN:Very preterm infants who attained independent oral feeding were prospectively assessed with an instrumented feeding bottle that measures nutritive sucking. The primary outcome measure was nutritive sucking pe...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105044
更新日期:2020-07-01 00:00:00
abstract::We report a breast-fed preterm infant (31 weeks gestation) who developed nutritional zinc deficiency 13 weeks post delivery. Serial samples of his mothers breast milk from early lactation (2 weeks post delivery) contained very low zinc concentrations, although her serum zinc and sweat zinc concentrations were normal. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90062-3
更新日期:1985-01-01 00:00:00
abstract::The objectives of this study were (1) to detect vasoactive intestinal polypeptide in fetal blood obtained by cordocentesis (2) to examine possible changes in growth retarded fetuses and to establish relationships between its levels and fetal blood acid-base status as well as fetal haemodynamics as assessed by Doppler ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)01610-2
更新日期:1995-03-17 00:00:00
abstract:AIM:The effects of intestinal bifidobacteria on the development of immunity in early life were explored. METHODS:Neonatal SD rats born and housed under strict barrier systems were fed from birth with sufficient antibiotics (bifidobacteria minimisation group) or supplemented daily with 1x10(10) colony-forming units of ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.01.002
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:This pilot study compared the physiological and behavioural changes in premature infants undergoing three different methods of screening for retinopathy of prematurity (ROP). STUDY DESIGN:Prospective randomized cross-over pilot study. SUBJECTS AND METHODS:Fifteen premature infants requiring screening for ROP ...
journal_title:Early human development
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.earlhumdev.2004.09.005
更新日期:2005-04-01 00:00:00
abstract::Newborn infants in critical conditions require a permanent intra-venous line to allow for the administration of fluids, parenteral nutrition and drugs. The use of central venous catheters, however, is associated with an increased risk of infections, leading to prolongation of length of stay and higher hospitalization ...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/S0378-3782(14)70017-9
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:In neonates with spina bifida aperta (SBA), leg movements by myotomes caudal to the meningomyelocele (MMC) are transiently observed. It is unclear whether these leg movements relate to functional neural conduction through the MMC. For optimal therapeutical intervention, pathophysiological insight in these ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.09.002
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:To assess the applicability of Drotar model when the diagnosis of congenital malformation is made antenatally. METHODS:In a 3-year period (2000-2003) fifty mothers, counselled for fetal malformations amenable to surgical correction at birth, were interviewed. Statistical associations were sought between each...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.12.010
更新日期:2006-10-01 00:00:00
abstract::We have investigated 20 healthy full-term newborns between the 4th and the 6th day of life in standard conditions for laterality of arm movements, before and after introduction of a target. The durations of recording were: (a) 5 min continuously before target introduction; (b) five 1-min units during target presentati...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(89)90099-6
更新日期:1989-04-01 00:00:00
abstract::A comparison has been made of protein accretion and growth in premature infants fed banked drip breast milk (BBM) or a preterm formula (PF). Protein accretion was calculated from the difference between dietary nitrogen intake and output in urine and stools, measured in a nutrient balance study. As expected, only the i...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90152-5
更新日期:1985-12-01 00:00:00
abstract::Anti-müllerian hormone (AMH) is a glycoprotein produced by immature Sertoli cells and responsible for the regression of müllerian ducts in male fetuses. The ontogeny of the hormone in early human development was investigated. While no detectable AMH could be found in female fetal serum, in males, the mean +/- S.E.M. A...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(93)90204-8
更新日期:1993-06-01 00:00:00
abstract:AIM:To assess whether attrition rate influences outcome in the follow-up of very preterm infants. STUDY DESIGN:In a national follow-up study of infants born alive in 1983 in the Netherlands with a gestational age less than 32 weeks and/or a birth weight less than 1500 g, outcome was assessed separately for adolescents...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.07.006
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Patent ductus arteriosus (PDA) is a frequent problem in preterm infants, and its incidence is inversely correlated with gestational age. The efficacy of medical treatment decreases with decreasing gestational age (GA), and failure rates as well as ductus ligation rates of 40% have been reported in <28 week G...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.06.012
更新日期:2010-08-01 00:00:00
abstract::Dramatic improvements have occurred in the overall health of our children driven by rigorous research translated into clinical practice. However, all is not well for too many, not only for their health but for other outcomes of their lives. These outcomes reflect poorly on how professional groups in child life and hea...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2014.08.022
更新日期:2014-11-01 00:00:00
abstract::Breast- and formula-fed infants were compared with regard to behavior patterns, especially crying behavior. A diary concerning seven behaviors was completed by 188 mothers of breast- and formula-fed infants at the well baby clinic. Breast-fed infants were fed more frequently with longer feeding duration. They slept mo...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(00)00071-2
更新日期:2000-05-01 00:00:00
abstract::Advances in pharmacology and technology have sharply reduced mortality of extremely preterm infants at the expense of an increasing number of survivors with handicaps and disabilities. The EURONIC study among neonatal intensive care units across Europe demonstrates that treatment of infants born at the limits of viabi...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.10.004
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:The second-to-fourth digit ratio (2D:4D) reflects prenatal estrogen and testosterone exposure, and is established in utero. Sex steroids are implicated in development and progression of primary brain tumors. AIMS:To investigate whether there is a link between 2D:4D ratio and primary brain tumors, and age at...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.10.003
更新日期:2016-12-01 00:00:00
abstract::The prone sleeping position has been identified in world-wide epidemiological studies as a major risk factor for sudden infant death syndrome (SIDS). Public awareness campaigns throughout the western world have led to an over 50% reduction in postneonatal mortality and frequency of SIDS. This reduction in mortality ha...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/s0378-3782(02)00025-7
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:There is concern that exposure of preterm infants to noxious insults over a prolonged period may have long term effects on their developing nervous system. AIMS:To investigate medium and long term effects of heel pricks in infants over the first year of life. STUDY DESIGN:Study 1-a longitudinal study, 2 da...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2007.09.018
更新日期:2008-06-01 00:00:00
abstract::Little is known about thrombopoietin (Tpo) production in human fetuses and neonates. As a step toward determining whether Tpo is relevant to platelet production in the fetus and neonate, we hypothesized that: (1) like other cytokines, Tpo is present in the cord blood in higher concentrations than in adult plasma; (2) ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(98)00077-2
更新日期:1999-01-01 00:00:00
abstract::The relationship between the traction forces used in 53 clinically indicated vacuum extractions and the incidence and degree of retinal hemorrhages observed in the neonates within 24 hours after birth was examined. A Vacuum Extractor Recorder (Type SF 30, Knick), was used to measure the traction force necessary for de...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(88)90107-7
更新日期:1988-03-01 00:00:00
abstract::Magnetic Resonance Imaging is becoming more widely available and increasingly important for imaging the neonatal brain. In newborn infants it poses challenges regarding patient preparation, safety, optimal timing, and sequence optimization. These issues are addressed in this paper and indications for performing neonat...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2008.11.009
更新日期:2009-02-01 00:00:00