Abstract：
PURPOSE:This pilot study compared the physiological and behavioural changes in premature infants undergoing three different methods of screening for retinopathy of prematurity (ROP). STUDY DESIGN:Prospective randomized cross-over pilot study. SUBJECTS AND METHODS:Fifteen premature infants requiring screening for ROP were recruited, and physiological and behavioural responses produced by three different methods of screening were compared. The screening methods employed a RetCam 120 and an indirect ophthalmoscope with and without an eyelid speculum. Physiological indices (change in pulse, mean blood pressure and oxygen saturation) and facial responses to pain (brow bulge, eye squeeze, nasolabial fold, mouth opening and the presence of cry) were recorded at five points: before, during and immediately after screening and 10 and 30 min after examination. RESULTS:Screening with the RetCam 120 and the indirect ophthalmoscope with a speculum both caused a greater change in pulse and mean blood pressure and an increase in facial responses to pain during and immediately after screening as compared to the indirect ophthalmoscope without the speculum. RetCam 120 screening caused greater desaturation than the other methods. CONCLUSIONS:Although this was a small sample which limits absolute conclusions, the study showed that screening using a RetCam or a speculum and indirect ophthalmoscope caused more stress to the infant, as indicated by physiological and behavioural changes, than simply screening using an indirect ophthalmoscope without a speculum. These effects should be considered when deciding on the appropriate screening method for examining particularly sick infants.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Mehta M,Adams GG,Bunce C,Xing W,Hill Mdoi
10.1016/j.earlhumdev.2004.09.005keywords:
subject
Has Abstractpub_date
2005-04-01 00:00:00pages
355-60issue
4eissn
0378-3782issn
1872-6232pii
S0378-3782(04)00156-2journal_volume
81pub_type
临床试验,杂志文章,随机对照试验abstract：BACKGROUND:Animal experiments have convincingly demonstrated that prenatal maternal stress affects pregnancy outcome and results in early programming of brain functions with permanent changes in neuroendocrine regulation and behaviour in offspring. AIM:To evaluate the existing evidence of comparable effects of prenata...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(02)00075-0
更新日期：2002-12-01 00:00:00
abstract：AIM:This study investigated the effect of aminophylline on behaviour and autonomic function in the preterm period. METHOD:Subjects were preterm infants cared for in the Oita University hospital from August 2012 to October 2014. The group that was administered aminophylline (Am+) and the group that received no aminophy...
journal_title：Early human development
pub_type： 杂志文章
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abstract：OBJECTIVE:We hypothesized that morphine has a depressing effect on early brain activity, assessed using quantitative aEEG/EEG parameter and depressed activity will be associated with brain volumes at term in extremely preterm infants. STUDY DESIGN:174 preterm infants were enrolled in 3 European tertiary NICUs (mean GA...
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2012-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.03.002
更新日期：2010-04-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.01.005
更新日期：2012-08-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2009.11.003
更新日期：2010-01-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,评审
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更新日期：1993-09-01 00:00:00
abstract：:The essential fatty acid (EFA) composition of umbilical vessel walls is increasingly being studied as a longer-term reflection of the fetal EFA status. We evaluated the EFA content of umbilical artery and vein vessel walls in 43 preterm infants and compared it with that of 43 full-term cord vessels. In addition, relat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01656-n
更新日期：1995-08-18 00:00:00
abstract：:Psychobiological studies of fetal ontogenesis in non-human species, particularly in laboratory rat, now have much to offer students of human development. Psychobiological approaches are 'ecologically' oriented which, for fetal research, implies consideration of the adaptive significance of behavior within the uterine ...
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pub_type： 杂志文章,评审
doi：10.1016/0378-3782(93)90102-z
更新日期：1993-12-31 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00114-1
更新日期：2001-04-01 00:00:00
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pub_type： 杂志文章
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更新日期：1993-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：1983-12-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2020-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2000-11-01 00:00:00
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更新日期：2019-08-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2017-10-01 00:00:00
abstract：:Serum albumin levels decrease during pregnancy while the concentration of most other maternal serum proteins of hepatic origin remain stable or increase. In a study of 289 women, most maternal characteristics such as race, age, smoking, a history of previous low birth-weight, infant sex and gestational age at delivery...
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pub_type： 杂志文章
doi：10.1016/0378-3782(93)90178-w
更新日期：1993-10-01 00:00:00
abstract：:The autonomy of patients participating in research means that a proper informed consent process must take place. This means that information must be given according to a reasonable person standard implying what legally and ethical a reasonable person participating in the research would want to know. The research must ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.04.025
更新日期：2018-09-01 00:00:00
abstract：:Posture and spontaneous motor patterns during the first days of life were studied in ten healthy fullterm infants by direct observation and videorecording. The aim of the study was to provide a description of motor and postural characteristics of normal newborns. The infants were recorded for 1 h on their first and fo...
journal_title：Early human development
pub_type： 杂志文章
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更新日期：1989-02-01 00:00:00
abstract：BACKGROUND:Maternal pre-pregnancy obesity, in term-born children, is associated with an increased risk of attention problems, however this relationship has not been explored among children born extremely preterm. AIM:To estimate the risk of attention problems at age 10years in children born very preterm to overweight ...
journal_title：Early human development
pub_type： 杂志文章,多中心研究
doi：10.1016/j.earlhumdev.2017.08.002
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Although highly beneficial, human milk feeding is challenging in preterm infants due to adverse NICU factors for the infant and mother. AIM:To investigate the effects of an early intervention in promoting infant's human milk feeding and acquisition of full oral feeding. METHODS:This study is part of a RCT....
journal_title：Early human development
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.earlhumdev.2018.04.016
更新日期：2018-06-01 00:00:00
