Abstract：
:Dramatic improvements have occurred in the overall health of our children driven by rigorous research translated into clinical practice. However, all is not well for too many, not only for their health but for other outcomes of their lives. These outcomes reflect poorly on how professional groups in child life and health have advocated effectively at the political level for the needs of children and for the services to support them. Professional staff in child health, including those involved in neonatal care, must become more effective in translating research into political advocacy for the best interests of children. A scientific approach to political advocacy is needed that is equivalent in its rigour to the best of bio-medical research. Above all, the care of the newly born infant should not be seen in isolation, but in the overall context of childhood and the services to support children today.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Kt AAdoi
10.1016/j.earlhumdev.2014.08.022subject
Has Abstractpub_date
2014-11-01 00:00:00pages
761-4issue
11eissn
0378-3782issn
1872-6232pii
S0378-3782(14)00208-4journal_volume
90pub_type
杂志文章,评审abstract：BACKGROUND:Visual cognitive functions of preverbal infants are evaluated by means of a behavioral assessment. Parents or primary caregivers may be appropriate to certify the acquisition of certain abilities. AIMS:To develop the PreViAs (Preverbal Visual Assessment) questionnaire to assess visual behavior of infants un...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.01.012
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:The second-to-fourth digit ratio (2D:4D) reflects prenatal estrogen and testosterone exposure, and is established in utero. Sex steroids are implicated in development and progression of primary brain tumors. AIMS:To investigate whether there is a link between 2D:4D ratio and primary brain tumors, and age at...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.10.003
更新日期：2016-12-01 00:00:00
abstract：:Serum albumin levels decrease during pregnancy while the concentration of most other maternal serum proteins of hepatic origin remain stable or increase. In a study of 289 women, most maternal characteristics such as race, age, smoking, a history of previous low birth-weight, infant sex and gestational age at delivery...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(93)90178-w
更新日期：1993-10-01 00:00:00
abstract：:The early progress of myelination was studied, by means of myelin basic protein (MBP) immunohistochemistry and luxol-fast-blue (LFB) staining, in the spinal cord, spinal nerve roots and brainstem of 66 fetuses and neonates. The degree of myelination was classified from 1 (slight) to 4 (mature). MBP immunoreactivity ex...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)01608-r
更新日期：1995-03-17 00:00:00
abstract：:Ultrastructural and immunohistochemical studies were made of the testicular interstitial tissue from eight human fetuses of 15 to 27 weeks gestation. Three cell types developed in mesenchymal cells: Leydig cells and peritubular cells, as already reported, and cells of the mononuclear phagocyte system (MPS), which are ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(89)90070-4
更新日期：1989-09-01 00:00:00
abstract：BACKGROUND:Controversial results have been reported on the effect of type of feeding on the level of fecal calprotectin in infants. OBJECTIVE:To assess fecal calprotectin levels in breast fed or nonbreast fed healthy infants. DESIGN:A study was conducted to compare fecal calprotectin in infants who were exclusively b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.06.005
更新日期：2014-09-01 00:00:00
abstract：:Pancreatic protease deficiency may be an aetiological factor in enteritis necroticans, a disease sharing some features of necrotising enterocolitis (NEC). Using faecal chymotrypsin measurement we have prospectively studied pancreatic exocrine function in infants at risk of NEC. No significant difference was found comp...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(93)90100-9
更新日期：1993-12-15 00:00:00
abstract：INTRODUCTION:Survivors of congenital diaphragmatic hernia have increased with the introduction of new treatment modalities and have been reported to experience ongoing medical morbidity until adulthood. AIM:To describe the long-term functional impact of congenital diaphragmatic repair on the survivors of a single inst...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.08.025
更新日期：2012-04-01 00:00:00
abstract：:We have shown for the first time that the microsomal glucose-6-phosphatase enzyme protein is present in human embryonic and fetal red blood cells and the ontogeny of its expression has been determined. In the earliest embryos, red cells are predominantly of the primitive megaloblastic type. Circulating red cells in th...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01626-e
更新日期：1995-06-21 00:00:00
abstract：BACKGROUND:The kidney is one organ which presents distinct morphology depending on GA; the classic references for kidney measurements were established several years ago and it is not certain if they are still accurate. AIM:To evaluate the renal maturity using a computer-assisted morphometry in autopsied fetuses within...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.01.013
更新日期：2006-11-01 00:00:00
abstract：AIM:To determine whether maternal state and trait anxiety levels affect fetal movements or fetal heart rate (FHR) in the third trimester. SUBJECTS:Forty-one healthy pregnant nulliparous women not on medication and with a singleton pregnancy. STUDY DESIGN:Maternal anxiety was assessed using the Spielberger State- Trai...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00256-0
更新日期：2002-04-01 00:00:00
abstract：:The study set out to document child care practices in as many different countries and cultures as possible with the aim of providing baseline child care data and stimulating new hypotheses to explain persisting differences in sudden infant death syndrome (SIDS) rates between countries. The protocol, piloted in four co...
journal_title：Early human development
pub_type： 杂志文章,多中心研究
doi：10.1016/s0378-3782(99)00021-3
更新日期：1999-06-01 00:00:00
abstract：:The premature birth of a child and admission to the neonatal intensive care unit (NICU) is a distressing experience for parents, and has been associated with symptoms of depression, anxiety and post-traumatic stress. Supporting parents in the NICU after preterm birth is critical not only for their own mental health, b...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2019.104838
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Children with major anatomical congenital anomalies (CA) often need prolonged hospitalization with surgical interventions in the neonatal period and thereafter. Better intensive care treatment has reduced mortality rates, but at the cost of more morbidity. AIM:To study motor-function and exercise capacity i...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.06.014
更新日期：2010-08-01 00:00:00
abstract：:Phosphatidylcholine (PC) is the predominant phospholipid in natural surfactant preparations. A metabolic intermediate, lyso-PC, is potentially injurious to the lungs. In the present study, tracheal aspirates from preterm babies with respiratory distress syndrome treated with surfactant were examined for the presence o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)01885-9
更新日期：1997-09-19 00:00:00
abstract：UNLABELLED:While the role of antiepileptic drug (AED) therapy in teratogenesis has widely been investigated, there are few prospective studies on later postnatal development in offspring of epileptic women in utero exposed. The aim of this study was a prospective investigation of the psychomotor development in a select...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(03)00083-5
更新日期：2003-11-01 00:00:00
abstract：:The aim of this study was to determine whether corticotropin-releasing hormone (CRH) regulates human trophoblast cell growth. The results showed that exogenous CRH significantly stimulated human trophoblast proliferation in first-trimester primary cultures. In vivo, CRH was strongly immunolocalised to cytotrophoblasti...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2004.04.010
更新日期：2004-08-01 00:00:00
abstract：INTRODUCTION:Many women with a bipolar disorder are of reproductive age and will need to continue lithium treatment during pregnancy. The teratogenic and perinatal effects of lithium are known, but not the long-term effects of lithium on neurodevelopment of the children. This study investigates growth, neurological, co...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.09.013
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:An increased risk of major congenital abnormalities after IVF and ICSI has been described, but underlying mechanisms are unclear. This study evaluates the effects of ovarian hyperstimulation, the in vitro procedure and time to pregnancy (TTP) - as proxy for the severity of subfertility - on the prevalence of...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.06.002
更新日期：2012-10-01 00:00:00
abstract：:In this study the seven postural responses selected by Vojta to evaluate neuromotor development were applied to 68 very low birth weight (VLBW) (greater than 1500 g) infants and to 28 healthy infants of normal birth weight (less than 2500 g). Of the 68 VLBW infants, 41 were small for gestational age and 27 appropriate...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90140-e
更新日期：1990-11-01 00:00:00
abstract：BACKGROUND:Birthweight is an important predictor of various fundamental aspects of childhood health and development. AIM:To examine the impact of birthweight on childhood balance performance classification and verify if this is replicable and consistent in different populations. STUDY DESIGN:Prospective birth cohort ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.01.010
更新日期：2019-03-01 00:00:00
abstract：:Pregnancy is characterized by physiological, endocrine and metabolic adaptations creating a pseudo-diabetogenic state of progressive insulin resistance. These adaptations occur to sustain continuous fetal requirements for nutrients and oxygen. Insulin resistance develops at the level of the skeletal muscle, and matern...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2016.01.008
更新日期：2016-03-01 00:00:00
abstract：:This century has seen marked improvement in perinatal outcomes but prematurity remains a problem the world over. To improve these results requires more attention to early pregnancy or even pre-pregnancy care. Control of pre-existing conditions, improved social behavior in nutrition, smoking cessation and other factors...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90064-n
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:Infants whose mothers had low serum pregnancy-associated plasma protein-A (PAPP-A) in the first trimester were observed to have intrauterine growth retardation. AIM:Suggesting that PAPP-A plays an important role in the availability and activity of insulin-like growth factors (IGFs), which affect growth, we ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.10.005
更新日期：2007-07-01 00:00:00
abstract：INTRODUCTION:Children born very preterm (VPT) are at increased risk of emotional and behavioral problems later in life. We aimed to determine the prevalence and spectrum of behavioral abnormalities at five years of age in VPT children. METHODS:Multi-center cohort study on 339 early-school aged children born at a gesta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105200
更新日期：2020-12-01 00:00:00
abstract：:Meconium aspiration syndrome (MAS) is a common neonatal problem and, sadly, results in acute and chronic respiratory morbidity. Although meconium aspiration can occur prior to delivery even in the absence of labour, in many infants this condition could be prevented by appropriate suctioning at birth. More accurate pre...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/0378-3782(95)01625-d
更新日期：1995-04-28 00:00:00
abstract：:The structural changes in the umbilical cord of full term fetuses from 18 cases of gestational diabetes were studied. All these were insulin-dependent and their blood glucose levels were well controlled. Light microscopy showed rupture and erosion of the endothelial lining of umbilical arteries resulting in increased ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90114-3
更新日期：1986-10-01 00:00:00
abstract：:This year is the 20th anniversary of the first successful trial of exogenous surfactant for respiratory distress syndrome in the newborn and it is perhaps a good time to review recent advances in basic science and clinical practice as they relate to surfactant therapy. ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(00)00122-5
更新日期：2001-03-01 00:00:00
abstract：BACKGROUND:There have been few research studies aimed at obtaining a better understanding of the prediction of subsequent respiratory morbidity at follow-up in infants with a previous history of bronchopulmonary dysplasia (BPD) living in low- and middle-income countries (LMIC). The aim of the present study was to ident...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.10.003
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVES:To investigate the effects of single and repeated courses of antenatal corticosteroids on brain growth in very preterm babies. DESIGN:Retrospective study of 110 very preterm babies delivered at a single University Teaching Hospital between 1992 and 1999 who had a full necropsy including detailed examination...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00144-x
更新日期：2001-07-01 00:00:00
