Abstract:
:The diagnosis, acute management and follow-up of neonates with haemolytic disease of the newborn (HDN) still represents a significant area of activity for maternity/neonatal services. ABO incompatability is now the single largest cause of HDN in the western world. However, with increasing knowledge at the molecular level, and closer liaison between neonatal paediatricians and haematologists, the diagnosis of non-immune causes of HDN is increasing. As these conditions have an inherited basis and therefore have implications for other family members (or future children), it remains a high priority for all neonatal paediatricians to achieve an accurate diagnosis in all cases of HDN. As the efficacy of phototherapy increases the role of exchange transfusion in acute management is rapidly decreasing. This makes gauging the appropriate time to intervene with exchange transfusion a difficult clinical decision, and guidelines appropriate to the spectrum of contemporary disease are required. In the future intravenous immunoglobulin and/or intramuscular metalloporphyrins may further reduce the need for exchange transfusion and continue to change the spectrum of HDN faced by neonatal paediatricians.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Roberts IAdoi
10.1016/j.earlhumdev.2008.06.005subject
Has Abstractpub_date
2008-08-01 00:00:00pages
515-23issue
8eissn
0378-3782issn
1872-6232pii
S0378-3782(08)00118-7journal_volume
84pub_type
杂志文章,实务指引,评审abstract::This study examined the risk factors for respiratory distress syndrome (RDS) in preterm infants from pregnancies complicated by placenta previa. Forty preterm infants born to mothers with placenta previa between January 1989 and December 1995 in a medical center were enrolled. Each of these patients was matched in ges...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(00)00121-3
更新日期:2001-01-01 00:00:00
abstract::Lipids have physical, chemical, and physiological properties that make them important factors in human nutrition. They form a group of compounds of varied chemical nature that have the common property of being soluble in organic solvents but insoluble in water. This basic property affects their digestion, absorption, ...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/s0378-3782(01)00211-0
更新日期:2001-11-01 00:00:00
abstract::The biochemical, dermatological and neurological motor disorders of biotinidase deficiency (multiple carboxylase deficiency) show a dramatic response to pharmacological doses of biotin. This condition is characterised by the accumulation of biocytin and depletion of biotin. Neuromuscular function returns to normal wit...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90086-6
更新日期:1985-09-01 00:00:00
abstract::Long-term respiratory morbidity is common, particularly in those born very prematurely and who have developed bronchopulmonary dysplasia (BPD), but it does occur in those without BPD and in infants born at term. A variety of neonatal strategies have been developed, all with short-term advantages, but meta-analyses of ...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2014.08.020
更新日期:2014-11-01 00:00:00
abstract::Eleven healthy fetuses between 36 and 39 weeks of gestation were studied during the active sleep state to examine effects of a 5-s vibratory acoustic stimulus on the baseline fetal heart rate and flow velocity waveform in the fetal internal carotid artery. There was an immediate marked rise in baseline fetal heart rat...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(89)90105-9
更新日期:1989-04-01 00:00:00
abstract::In planning enteral feeding in the preterm infant, decisions need to be made regarding the feeding schedule, choice of milk, and the route of administration. Feeds should be commenced within a week after birth beginning with subnutritional quantities. Preterm human milk from the infant's own mother is the milk of choi...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/s0378-3782(99)00047-x
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. AIMS:To evaluate the effects of an early post-discharge d...
journal_title:Early human development
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.earlhumdev.2006.01.011
更新日期:2006-10-01 00:00:00
abstract::Stress due to earthquakes and other natural catastrophic events may result in a decline in the male to female ratio of newborn infants. One reason may be an increased death of male fetuses 3-5 months earlier. Another reason may relate to reduced conception of males and/or early male embryo demise 8-10 months earlier. ...
journal_title:Early human development
pub_type: 杂志文章,实务指引
doi:10.1016/j.earlhumdev.2019.104859
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:The male-to-female ratio of live births is expressed as the ratio of male births divided by total births (M/F). Males are produced approximately 3% in excess. A large number of factors have been found to influence M/F. Stress and privation reduces M/F. Gender preference (which almost invariably favours mal...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.10.013
更新日期:2015-12-01 00:00:00
abstract::One hundred consecutive cranial computed tomographic scans were reviewed in children aged 0-2 years, presenting to the Royal Belfast Hospital for Sick Children. The mean age at scanning was 8.3 months and 73% of the scans were abnormal. The majority of scans were performed electively (78%). The commonest indication fo...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(91)90011-q
更新日期:1991-08-01 00:00:00
abstract::The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alt...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(86)90186-6
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:Some researchers have developed child feeding indices to summarize child feeding practices so that they can compare child feeding practices across countries and monitor changes over time within a given country. AIMS:An adapted version of the infant and child feeding index (ICFI) developed by Ruel and Menon ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2008.10.009
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Preterm children have problems with mathematics but knowledge about the predictors of specific mathematic abilities in preterm populations is scarce. AIMS:This study investigated neurodevelopmental pathways to children's general and specific mathematic abilities across the full gestational age range. STUDY...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.07.015
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Routine oropharyngeal suctioning in term vigorous neonates immediately after birth is a questionable practice. Current recommendations favor suctioning only in the presence of considerable obstruction due to secretions, blood or other matter. We aimed to analyze the influence of oropharyngeal suctioning on c...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.01.005
更新日期:2015-02-01 00:00:00
abstract::A cohort study was carried out to assess the association between glucose-6-phosphate dehydrogenase (G6PD) deficiency, diagnosed by quantitative enzyme assay, and neonatal hyperbilirubinemia, defined as serum total bilirubin >/=15 mg/dl, in the well-baby nursery of Chang Gung Children's Hospital. Among 42,110 inborn in...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(03)00002-1
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVES:To determine whether early mortality (first year of life) risks among small for gestational age (SGA) neonates were similar regardless of SGA subtype based on three chronological classifications (term, preterm and post-term). STUDY DESIGN:Retrospective cohort study on all singleton live births in the United...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2006.05.008
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:To compare measurements of the upper arm cross-sectional areas (total arm area, arm muscle area, and arm fat area of healthy neonates) as calculated using anthropometry with the values obtained by ultrasonography. MATERIALS AND METHODS:This study was performed on 60 consecutively born healthy neonates: gesta...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(98)00085-1
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:To 1) define predictors of parent presence, any holding, holding in arms, and skin-to-skin care in the NICU and 2) investigate the relationships between parent participation and a) early neurobehavior and b) developmental outcomes at age 4 to 5years among preterm infants. METHODS:Eighty-one preterm infants b...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2017.12.008
更新日期:2018-02-01 00:00:00
abstract::Infants born at term frequently require mechanical ventilation and suffer significant mortality and morbidity. Yet, there have been few randomised trials (RCTs) exclusively of term born infants and when term born infants have been included in studies, a sub-analysis of their results has rarely been undertaken. The lim...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2012.09.012
更新日期:2012-12-01 00:00:00
abstract:AIM:This study investigated the effect of aminophylline on behaviour and autonomic function in the preterm period. METHOD:Subjects were preterm infants cared for in the Oita University hospital from August 2012 to October 2014. The group that was administered aminophylline (Am+) and the group that received no aminophy...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.04.011
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:The second-to-fourth digit ratio (2D:4D) reflects prenatal estrogen and testosterone exposure, and is established in utero. Sex steroids are implicated in development and progression of primary brain tumors. AIMS:To investigate whether there is a link between 2D:4D ratio and primary brain tumors, and age at...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.10.003
更新日期:2016-12-01 00:00:00
abstract::There is convincing evidence that breast-feeding is protective against gastro-enteritis and diarrhoea, but for other infections the situation is less clear cut. There is evidence that breast-fed infants are at increased risk of one infection (infant botulism). They are probably not significantly protected from upper r...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00056-x
更新日期:1997-10-29 00:00:00
abstract::There is increasing evidence that sleep plays a major role in the development of neural pathways in the neonatal brain. Several studies have suggested evidence-based approaches to improve sleep for infants admitted to the neonatal intensive care unit (NICU); however, in many neonatal centers very few of these strategi...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2017.07.002
更新日期:2017-10-01 00:00:00
abstract::Pulse oximetry screening for critical congenital heart defects (CCHDs) is a highly specific, moderately sensitive test which is cost effective, acceptable to both clinical staff and parents and meets the criteria for universal screening. Pulse oximetry screening is gaining considerable worldwide support and last year ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.09.013
更新日期:2012-12-01 00:00:00
abstract:AIMS:1. To determine the survival and morbidity of infants at discharge with a birthweight of less than 1500 g in the geographically defined population of East Anglia. 2. To demonstrate a cost-effective method of regional data collection. 3. To determine whether there were any changes in the demand for neonatal care. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.10.019
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVES:To investigate the effects of single and repeated courses of antenatal corticosteroids on brain growth in very preterm babies. DESIGN:Retrospective study of 110 very preterm babies delivered at a single University Teaching Hospital between 1992 and 1999 who had a full necropsy including detailed examination...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(01)00144-x
更新日期:2001-07-01 00:00:00
abstract::The calculation of descriptive statistics after data collection provides researchers with an overview of the shape and nature of their datasets, along with basic descriptors, and may help identify true or incorrect outlier values. This exercise should always precede inferential statistics, when possible. This paper pr...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.02.015
更新日期:2018-03-01 00:00:00
abstract::Dramatic improvements have occurred in the overall health of our children driven by rigorous research translated into clinical practice. However, all is not well for too many, not only for their health but for other outcomes of their lives. These outcomes reflect poorly on how professional groups in child life and hea...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2014.08.022
更新日期:2014-11-01 00:00:00
abstract::The essential fatty acid (EFA) composition of umbilical vessel walls is increasingly being studied as a longer-term reflection of the fetal EFA status. We evaluated the EFA content of umbilical artery and vein vessel walls in 43 preterm infants and compared it with that of 43 full-term cord vessels. In addition, relat...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(95)01656-n
更新日期:1995-08-18 00:00:00
abstract:BACKGROUND:Tyrosine hydroxylase (TH) is a specific marker for catecholaminergic neurones. Some reports have demonstrated a decrease of TH in the Sudden Infant Death Syndrome (SIDS) compared with controls. To further investigate this, the correlation between TH and sleep apnea was investigated here. MATERIALS AND METHO...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2003.08.007
更新日期:2003-12-01 00:00:00