Abstract:
:Lipids have physical, chemical, and physiological properties that make them important factors in human nutrition. They form a group of compounds of varied chemical nature that have the common property of being soluble in organic solvents but insoluble in water. This basic property affects their digestion, absorption, and transport in the blood and metabolism at cellular level. Firstly, fatty-acid chain length and number of double bonds influence fat absorption. Thus, medium-chain fatty acids (MCFA) are better absorbed than long-chain fatty acids. Secondly, the positional distribution of fatty acids (FA) in dietary triglycerides (TG) determine whether FA are absorbed as 2-monoglycerides (2-MG) or free fatty acids (FFA), and hence, influences the composition of chylomicroms (CM) because triglycerides (TG) are resyntethysed in the intestinal mucosa using 2-MG from dietary lipids. Generally, the absorption of FA in the sn-2 position of TG is favored, whereas no specificity has been found for the fatty acids in the sn-1 and sn-3 positions. Finally, some FA of nutritional interest, namely, long-chain polyunsaturated fatty acids (LCP), are present in dietary lipid sources as both TG or phospholipids (PL). Fatty acids esterified as PL or TG may show different availability. In fact, some authors have suggested a better absorption of LCP-PL. Moreover, dietary LCP in form of TG or PL differently affects the composition of HDL and LDL PL.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Ramírez M,Amate L,Gil Adoi
10.1016/s0378-3782(01)00211-0keywords:
subject
Has Abstractpub_date
2001-11-01 00:00:00pages
S95-S101eissn
0378-3782issn
1872-6232pii
S0378378201002110journal_volume
65 Supplpub_type
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journal_title:Early human development
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journal_title:Early human development
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pub_type: 历史文章,杂志文章,评审
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.07.004
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journal_title:Early human development
pub_type: 杂志文章
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