Abstract：
:Infants born at term frequently require mechanical ventilation and suffer significant mortality and morbidity. Yet, there have been few randomised trials (RCTs) exclusively of term born infants and when term born infants have been included in studies, a sub-analysis of their results has rarely been undertaken. The limited evidence demonstrates in term born infants that there are no benefits in using rates >60bpm during conventional mechanical ventilation (CMV) or using synchronous intermittent mandatory ventilation. Pressure support ventilation may reduce their work of breathing (WOB). During volume targeted ventilation, a volume targeted (VT) level of 6mls/kg reduces the WOB compared to a lower level or no VT. High frequency oscillatory ventilation in infants born at or near term with severe respiratory failure does not reduce mortality, oxygen dependency at 28 days or intracranial haemorrhage. RCTs with long term outcome are required to determine the optimum ventilatory modes in term born infants.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Greenough A,Bhat Pdoi
10.1016/j.earlhumdev.2012.09.012subject
Has Abstractpub_date
2012-12-01 00:00:00pages
921-3issue
12eissn
0378-3782issn
1872-6232pii
S0378-3782(12)00234-4journal_volume
88pub_type
杂志文章,评审abstract：BACKGROUND:Hydatidiform mole is an abnormal pregnancy with over-proliferation of the placenta, which causes the dysfunction of placenta. Although more than 80% of hydatidiform moles are benign with good outcome, hydatidiform moles are associated with developing very early onset preeclampsia. However the association bet...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.02.008
更新日期：2013-08-01 00:00:00
abstract：:Pulse oximetry screening is a highly specific, moderately sensitive test for detecting critical congenital heart defects (CCHDs) that meets the criteria for universal screening. The possibility of using pulse oximetry as a screening test was first investigated over 10 years ago and since then data from more than 370,0...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)50006-0
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Somatosensory evoked potentials (SEPs) offer an additional bedside tool for outcome prediction after perinatal asphyxia. AIMS:To assess the reliability of SEPs recorded with bifrontoparietal amplitude-integrated electroencephalography (aEEG) brain monitoring setup for outcome prediction in asphyxiated newbo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105287
更新日期：2021-02-01 00:00:00
abstract：:We have investigated infant-caregiver interactions in an isolated African subsistence farming community where women perform arduous agricultural tasks in addition to their normal domestic duties which include child care. 49 babies aged 3-18 months were studied on one or two occasions. Detailed observations were made o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90139-2
更新日期：1985-10-01 00:00:00
abstract：BACKGROUND:The entorhinal cortex serves as an important gateway between the cerebral cortex and the hippocampus by receiving afferent information from limbic, modality sensory-specific, and multimodal association fibers from all the brain lobes. AIM:To investigate whether thinning of entorhinal cortex is associated wi...
journal_title：Early human development
pub_type： 临床试验,杂志文章
doi：10.1016/j.earlhumdev.2011.07.017
更新日期：2012-02-01 00:00:00
abstract：:Insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-1 (IGFBP-1) were measured in amniotic fluid, extraembryonic coelomic fluid and maternal serum from 23 women with apparently normal first trimester pregnancies prior to termination. The levels of IGF-1 and IGFBP-1 were significantly hig...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90105-p
更新日期：1992-02-01 00:00:00
abstract：BACKGROUND:Obstetrical and neonatal complications and/or an adverse parenting environment are risk factors for language impairment, but little is known about their effects on early word production (late talking). AIMS:To determine obstetrical and neonatal risk factors in children with delayed word production; to asses...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.05.009
更新日期：2007-02-01 00:00:00
abstract：:A significant improvement has been achieved in perinatal mortality figures during the last decade in Japan with a neonatal mortality rate of 2.6 and a stillbirth rate of 4.1 for 1989. With its unique obstetric and neonatal services, there are advantages and also disadvantages in respect of clinical and basic research....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90185-j
更新日期：1992-06-01 00:00:00
abstract：:The calculation of descriptive statistics includes the calculation of standard error and confidence interval, an inevitable component of data analysis in inferential statistics. This paper provides pointers as to how to do this in Microsoft Excel™. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.01.013
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:Recent evidence suggests that cord insertion type of one twin correlates with chorionic plate vascularization of the monochorionic co-twin. Specifically, for twins with paracentral cords, chorionic plate vascularization is significantly greater when the co-twin has a velamentous, rather than paracentral cord...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.01.009
更新日期：2013-04-01 00:00:00
abstract：:Intrauterine growth restriction (IUGR) is associated with altered lung development in human and rat. The transcription factor PPARγ, is thought to contribute to lung development. PPARγ is activated by docosahexanoic acid (DHA). One contribution of PPARγ to lung development may be its direct regulation of chromatin mod...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.08.026
更新日期：2010-12-01 00:00:00
abstract：:Gastro-oesophageal reflux (GOR) and gastro-oesophageal reflux disease (GORD) occur frequently during the first months of life. Gastro-oesophageal reflux may be a primary gastro-intestinal motility disorder, but it may also be secondary to other conditions such as cow's milk protein allergy. Objective diagnosis can be ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2005.10.011
更新日期：2005-12-01 00:00:00
abstract：:There is a wide differential diagnosis of early onset respiratory distress especially in term babies, and interstitial lung disease (chILD) is a rare but important consideration in this context. chILD manifesting immediately after birth is usually related to mutations in surfactant protein genes, or conditions related...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105186
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Neonatal Encephalopathy (NE) is a prominent cause of infant mortality and neurodevelopmental disability. Hypothermia is an effective neuroprotective therapy for newborns with encephalopathy. Post-hypothermia functional-anatomical correlation between neonatal neurobehavioral abnormalities and brain injury fin...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.05.006
更新日期：2013-09-01 00:00:00
abstract：:The objectives of this study were (1) to detect vasoactive intestinal polypeptide in fetal blood obtained by cordocentesis (2) to examine possible changes in growth retarded fetuses and to establish relationships between its levels and fetal blood acid-base status as well as fetal haemodynamics as assessed by Doppler ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)01610-2
更新日期：1995-03-17 00:00:00
abstract：:Comparisons of the components of ventilator waveform were made in two groups of preterm infants ventilated for the respiratory distress syndrome. Infants actively expiring against positive pressure inflation were compared to infants not showing this interaction. The actively expiring infants were ventilated with a hig...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(88)80051-3
更新日期：1988-05-01 00:00:00
abstract：:More than 10,000 preterm babies worldwide have been enrolled in trials evaluating probiotics administration for the prevention of necrotising enterocolitis, with very few adverse events reported. Despite this, probiotic safety is frequently cited as a concern when using this intervention. This review addresses why a p...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2019.05.016
更新日期：2019-08-01 00:00:00
abstract：:We have shown for the first time that the microsomal glucose-6-phosphatase enzyme protein is present in human embryonic and fetal red blood cells and the ontogeny of its expression has been determined. In the earliest embryos, red cells are predominantly of the primitive megaloblastic type. Circulating red cells in th...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01626-e
更新日期：1995-06-21 00:00:00
abstract：:To determine the assessments before discharge from the intensive care unit, that will predict outcome most accurately, a prospective longitudinal study in a cohort of 79 high risk VLBW children was conducted from birth to 3.6 years of age. Birthweight, gestational age, obstetrical and neonatal optimality, neonatal neu...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90040-n
更新日期：1992-12-01 00:00:00
abstract：BACKGROUND:Mothers have been shown to have higher morning cortisol on days they go to work compared to non-workdays; however, it is unknown how maternal workday associates with child morning cortisol or the attunement of mother-child morning cortisol. AIMS:This study examined the presence and stability of morning cort...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.11.007
更新日期：2014-01-01 00:00:00
abstract：:A fetus with signs of hydrops is at high risk of intrauterine death. The pathophysiology of hydrops fetalis is still unclear. We found decreased concentrations of cyclic guanosine monophosphate in fetal plasma of alloimmunized pregnancies complicated by hydrops fetalis, which might suggest reduced nitric oxide product...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00063-8
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:Studies on motor performance and its early markers are rare in China, especially in very low birth weight (VLBW) infants. OBJECTIVE:Apart from the assessment of the inter-scorer agreement, we aimed to analyze to what extent the motor repertoire at 10 to 18weeks postterm was related to neonatal complications...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.03.010
更新日期：2016-09-01 00:00:00
abstract：:This project aimed to assess the accuracy of Tempa-DOT and FeverScan for measuring children's temperatures. Tempa-DOT is a small flat chemical thermometer with 50 dots that change colour at specific temperatures. FeverScan is a liquid crystal strip thermometer with temperature sensitive colour bars that change colour ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00050-4
更新日期：1998-12-01 00:00:00
abstract：:Fifty-five pregnant Rhesus isoimmunized women were subjected to fetal blood sampling or fetal blood transfusion on 135 occasions. Glucose and C-peptide concentrations were measured in fetal blood, in addition to the routine investigations for complete blood count, blood gases and lactate concentration, in order to inv...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90027-g
更新日期：1990-12-01 00:00:00
abstract：:Cord blood thyroxine (T4) concentrations were measured in 4,068 infants from 28 wk gestation to term. Each chart was reviewed for the following factors: delivery by cesarean section, prolonged rupture of membranes, neonatal asphyxia, meconium-stained amniotic fluid, maternal diabetes mellitus and twinning. Each neonat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(78)90031-2
更新日期：1978-09-01 00:00:00
abstract：:The reported energy content of infant formulas will vary, depending upon the method used to calculate or measure the caloric value. Manufacturers' specifications regarding the energy content of milk formulas reflects the 'metabolizable' energy. i.e., the amount of energy which is digested and absorbed by the infant. H...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(82)90124-4
更新日期：1982-07-01 00:00:00
abstract：:In planning enteral feeding in the preterm infant, decisions need to be made regarding the feeding schedule, choice of milk, and the route of administration. Feeds should be commenced within a week after birth beginning with subnutritional quantities. Preterm human milk from the infant's own mother is the milk of choi...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(99)00047-x
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the preschool neurodevelopmental outcome in CDH survivors between 2 and 5 years of age and to identify perinatal and postnatal factors that may be predictive of persistent neurological deficits. METHODS:The study cohort consists of 60 CDH survivors that were enrolled in our prospective, follow-up...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.12.009
更新日期：2013-06-01 00:00:00
abstract：:The autonomy of patients participating in research means that a proper informed consent process must take place. This means that information must be given according to a reasonable person standard implying what legally and ethical a reasonable person participating in the research would want to know. The research must ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.04.025
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Intrauterine growth restriction (IUGR) is a fetal condition characterized by growth-rate reduction. Afflicted fetuses tend to display abnormalities in heart rate. OBJECTIVE:To study the differences in the heart-rate variability of low-risk fetuses and IUGR fetuses during different behavioral states. METHOD...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.07.002
更新日期：2013-10-01 00:00:00
