Abstract:
:Fifty-five pregnant Rhesus isoimmunized women were subjected to fetal blood sampling or fetal blood transfusion on 135 occasions. Glucose and C-peptide concentrations were measured in fetal blood, in addition to the routine investigations for complete blood count, blood gases and lactate concentration, in order to investigate whether fetal insulin secretion was affected by hypoxia from fetal anemia. We found a strong relation between the concentration of C-peptide and gestational age at sampling (r = 0.53, P less than or equal to 0.000001). Multiple regression analysis also demonstrated that glucose (P less than or equal to 0.0051) and lactate (P less than or equal to 0.0003) also affected the concentration of C-peptide. We were unable to find any relation between C-peptide concentrations and blood gas variables. We conclude that fetal insulin secretion, measured as C-peptide concentration in fetal blood, is not affected by hypoxia from anemia as long as hemoglobin concentration remains within the range 2.1-14.8 g/dl).
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Stangenberg M,Sasidharan Pdoi
10.1016/0378-3782(90)90027-gsubject
Has Abstractpub_date
1990-12-01 00:00:00pages
201-8issue
3eissn
0378-3782issn
1872-6232pii
0378-3782(90)90027-Gjournal_volume
24pub_type
杂志文章abstract::Doctors are frequently depicted as important protagonists in science fiction, including in the science fiction franchise Star Trek. This paper will profile Drs. Philip Boyce and Mark Piper from the first two Star Trek pilot episodes. These doctors are interdisciplinarians with a variety of skills that permit them to c...
journal_title:Early human development
pub_type: 杂志文章,实务指引
doi:10.1016/j.earlhumdev.2020.104988
更新日期:2020-05-01 00:00:00
abstract::We have investigated 20 healthy full-term newborns between the 4th and the 6th day of life in standard conditions for laterality of arm movements, before and after introduction of a target. The durations of recording were: (a) 5 min continuously before target introduction; (b) five 1-min units during target presentati...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(89)90099-6
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND:Preterm children have problems with mathematics but knowledge about the predictors of specific mathematic abilities in preterm populations is scarce. AIMS:This study investigated neurodevelopmental pathways to children's general and specific mathematic abilities across the full gestational age range. STUDY...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.07.015
更新日期:2014-10-01 00:00:00
abstract::Index and regression methods of selecting babies whose heads are out of proportion to their body weight are examined and compared. The ratios head circumference3/birthweight and head circumference3/birthweightP (where P is a power found by regression methods) are used, and the regression of head circumference 3 on bir...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(80)90039-0
更新日期:1980-12-01 00:00:00
abstract:BACKGROUND:Children born preterm are at risk of visuospatial attention orienting and processing dysfunctions, which can be quantified early in life using visually-guided eye movement responses. AIMS:To identify the prevalence and perinatal risk factors for visuospatial attention orienting and processing dysfunctions i...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2019.01.015
更新日期:2019-03-01 00:00:00
abstract::Human and animal studies demonstrate that uteroplacental insufficiency and subsequent intrauterine growth retardation (IUGR) decrease intestinal growth and lead to both an increased incidence of feeding intolerance and necrotizing enterocolitis. Our objective was to determine the effects of uteroplacental insufficienc...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.04.015
更新日期:2004-09-01 00:00:00
abstract::To determine the assessments before discharge from the intensive care unit, that will predict outcome most accurately, a prospective longitudinal study in a cohort of 79 high risk VLBW children was conducted from birth to 3.6 years of age. Birthweight, gestational age, obstetrical and neonatal optimality, neonatal neu...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(92)90040-n
更新日期:1992-12-01 00:00:00
abstract::Low birthweight has been associated with diseases and disorders later in life. It has been suggested that this is caused by the impaired development of abdominal organs, especially in cases of growth retardation. Besides general malnutrition of the fetus, preferential bloodflow to the heart and brain may further depri...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00073-x
更新日期:1998-04-17 00:00:00
abstract:INTRODUCTION:The male-to-female ratio of live births is expressed as the ratio of male births divided by total births (M/F). Males are produced approximately 3% in excess. A large number of factors have been found to influence M/F. Stress and privation reduces M/F. Gender preference (which almost invariably favours mal...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.10.013
更新日期:2015-12-01 00:00:00
abstract::Modifications of brain-stem acoustic evoked potentials (BAEPs) in the first 5 days of life of normal full-term infants are reported. BAEPs were recorded using rarefaction clicks at 70, 60, 40, 20 dB HL. Multiple linear regression analysis was performed to evaluate chronological and gestational age differences for all ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(91)90034-z
更新日期:1991-11-01 00:00:00
abstract:AIM:To determine whether maternal state and trait anxiety levels affect fetal movements or fetal heart rate (FHR) in the third trimester. SUBJECTS:Forty-one healthy pregnant nulliparous women not on medication and with a singleton pregnancy. STUDY DESIGN:Maternal anxiety was assessed using the Spielberger State- Trai...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(01)00256-0
更新日期:2002-04-01 00:00:00
abstract::The presence of dilated bowel loops antenatally suggests fetal bowel obstruction. Neonatal intestinal obstruction can have different variations in presentation depending on the level and extent of obstruction. Some of these conditions can be diagnosed antenatally. Antenatal detection of surgically correctable anomalie...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2006.02.005
更新日期:2006-05-01 00:00:00
abstract::This study examined the risk factors for respiratory distress syndrome (RDS) in preterm infants from pregnancies complicated by placenta previa. Forty preterm infants born to mothers with placenta previa between January 1989 and December 1995 in a medical center were enrolled. Each of these patients was matched in ges...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(00)00121-3
更新日期:2001-01-01 00:00:00
abstract::Fourteen infants of 2 months or 6 months of age were video-recorded during polysomnography. Four were normal infants, five had a history of ALTE (apparent life threatening event) and five had repeated and prolonged apnoea during sleep. Two ALTE infants have been recorded at 2 months as well as at 6 months of age. Move...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90098-1
更新日期:1994-12-16 00:00:00
abstract::Lipids have physical, chemical, and physiological properties that make them important factors in human nutrition. They form a group of compounds of varied chemical nature that have the common property of being soluble in organic solvents but insoluble in water. This basic property affects their digestion, absorption, ...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/s0378-3782(01)00211-0
更新日期:2001-11-01 00:00:00
abstract::It is convenient to calculate milk energy from the creamatocrit but in order to assess the accuracy with which energy content can be predicted in this way, the creamatocrit, the percentage of carbon, and the calorie value of milk were determined in 11 samples of pooled pasteurised human milk. The calculated milk energ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90121-5
更新日期:1985-05-01 00:00:00
abstract::This century has seen marked improvement in perinatal outcomes but prematurity remains a problem the world over. To improve these results requires more attention to early pregnancy or even pre-pregnancy care. Control of pre-existing conditions, improved social behavior in nutrition, smoking cessation and other factors...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(92)90064-n
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND:Tyrosine hydroxylase (TH) is a specific marker for catecholaminergic neurones. Some reports have demonstrated a decrease of TH in the Sudden Infant Death Syndrome (SIDS) compared with controls. To further investigate this, the correlation between TH and sleep apnea was investigated here. MATERIALS AND METHO...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2003.08.007
更新日期:2003-12-01 00:00:00
abstract::Nearly 10% of premature infants are born very preterm at 32weeks gestational age or less in the United States. Up to 35% of these very preterm survivors are at risk for cognitive and behavioral deficits. Yet accurate diagnosis of such deficits cannot be made until early childhood. Resting-state fMRI provides noninvasi...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.06.002
更新日期:2016-07-01 00:00:00
abstract::Among 7 subjects with hyperemesis gravidarum (HG), we found gabapentin therapy to be associated with mean reductions in nausea and emesis from Baseline to Days 12-14 of 80% and 94%, respectively. There have been 2 congenital defects among 7 exposed infants. Gabapentin may be effective in the treatment of HG. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2009.11.003
更新日期:2010-01-01 00:00:00
abstract::The IPAT Anxiety Scale was administered to a large sample of primiparous women from an economically disadvantaged population in their third trimester of pregnancy. At birth and at three and six months postpartum, the infants and mothers were assessed using a variety of behavioral and standardized procedures. Results i...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(81)90034-7
更新日期:1981-07-01 00:00:00
abstract::Unexpected death in infancy may be a consequence of recognisable pathophysiological processes, or may remain unexplained after thorough investigation. We review the appropriate investigations that should be performed after unexpected infant deaths, and the recent changes to UK law that will make such investigations ma...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2006.09.012
更新日期:2006-12-01 00:00:00
abstract::Interfacility transport to tertiary care for high-risk neonates has become an integral part of equitable access to optimal perinatal healthcare. Excellence in clinical care requires expertise in transport medicine and the coordination of safe transport processes. However, concerns remain regarding environmental stress...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2020.105051
更新日期:2020-07-01 00:00:00
abstract::Ninety five placentae from normal term and 'normal' preterm pregnancies have been analysed by morphometry. The growth of the whole placenta, of the microscopic placental constituents and of the villous surface area has been measured in placentae from uncomplicated pregnancies from 10 weeks of gestation to term to prov...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(84)90074-4
更新日期:1984-06-01 00:00:00
abstract::The brain glycoconjugates, glycosidases and lipids have been studied in a case of human congenital athyroidism never treated with hormonal replacement. Increase of membrane-bound mucopolysaccharides has been found in the grey matter. Total lipids in the white matter, and phospholipids, and total glycolipids and choles...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(83)90009-9
更新日期:1983-10-01 00:00:00
abstract::Near infrared spectroscopy (NIRS) monitoring is a new challenge for clinicians who deal with early detection of dangerous hypoperfusion in the brain, as well as in splanchnic and renal districts in critically ill preterm infants. Previous studies performed on infants and children with congenital heart disease, demonst...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/S0378-3782(13)70014-8
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Non-nutritive suck (NNS) is one piece of the complex oral feeding process, yet there is paucity on how it develops throughout the first year of life. AIMS:To determine changes in infant NNS between 3 and 12 months of age. STUDY DESIGN:Twenty-six full-term infants (65% male) completed this study. All infant...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105141
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND AIMS:The interaction between the infant and the caregiver is stated to be very important in the development of a child. When there is inadequacy of interaction, several emotional and developmental problems can emerge. We aimed to investigate the socio-demographic and clinical features of children diagnos...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.09.004
更新日期:2012-06-01 00:00:00
abstract::Behavioural state observations were carried out on 12 fetuses which subsequently had birthweights below the 10th percentile. Their gestational ages at the time of study ranged from 32 to 40 weeks. Real-time ultrasound scanning was used to detect fetal body and eye movements, and the fetal heart rate was continuously r...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90181-1
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:Long-lasting respiratory symptoms have a huge impact on the quality of life in prematurely born children. AIMS:We aimed to investigate the perinatal and maternal risk factors involved in the development of chronic respiratory morbidity in preterm infants, with an emphasis on the importance of Foetal Inflamm...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.07.002
更新日期:2014-09-01 00:00:00