Abstract：
:Eleven healthy fetuses between 36 and 39 weeks of gestation were studied during the active sleep state to examine effects of a 5-s vibratory acoustic stimulus on the baseline fetal heart rate and flow velocity waveform in the fetal internal carotid artery. There was an immediate marked rise in baseline fetal heart rate with concomitant drop in pulsatility index in the flow velocity waveform of the fetal internal carotid artery, which persisted for at least 15 min after the stimulus. However, when the pulsatility index was standardized for a fetal heart rate of 140 beats/min this index remained virtually unaltered. These data suggest that in the healthy term fetus during active sleep state, a vibratory acoustic stimulus has no measurable effect on cerebral vascular resistance. Since virtually all reported studies on vibratory acoustic stimulation of the fetus were carried-out during the quiet sleep state, the data from the present study do not provide any information on the safety of this device when employed as a means of assessing of fetal well-being.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Wladimiroff JW,Cheung Kdoi
10.1016/0378-3782(89)90105-9subject
Has Abstractpub_date
1989-04-01 00:00:00pages
61-6issue
1eissn
0378-3782issn
1872-6232pii
0378-3782(89)90105-9journal_volume
19pub_type
杂志文章abstract：BACKGROUND:Prior studies have shown that children with congenital hearing loss have increased rates of behavior disorders. Child hearing loss has also been reported to be associated with increased maternal stress. Little is known about the behavior or the predictors of behavioral outcomes of children with hearing loss ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.06.006
更新日期：2011-12-01 00:00:00
abstract：:Modifications of brain-stem acoustic evoked potentials (BAEPs) in the first 5 days of life of normal full-term infants are reported. BAEPs were recorded using rarefaction clicks at 70, 60, 40, 20 dB HL. Multiple linear regression analysis was performed to evaluate chronological and gestational age differences for all ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(91)90034-z
更新日期：1991-11-01 00:00:00
abstract：BACKGROUND:In severe intrauterine growth restriction (IUGR) due to placental insufficiency a haemodynamic adaptation occurs, resulting in preferential blood flow to the fetal brain (brain sparing). With Doppler ultrasound an increased ratio between the umbilical and the cerebral artery pulsatility index (U/C ratio) can...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.04.007
更新日期：2010-06-01 00:00:00
abstract：:Pancreatic protease deficiency may be an aetiological factor in enteritis necroticans, a disease sharing some features of necrotising enterocolitis (NEC). Using faecal chymotrypsin measurement we have prospectively studied pancreatic exocrine function in infants at risk of NEC. No significant difference was found comp...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(93)90100-9
更新日期：1993-12-15 00:00:00
abstract：BACKGROUND:Children born preterm are at risk of visuospatial attention orienting and processing dysfunctions, which can be quantified early in life using visually-guided eye movement responses. AIMS:To identify the prevalence and perinatal risk factors for visuospatial attention orienting and processing dysfunctions i...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.01.015
更新日期：2019-03-01 00:00:00
abstract：:During the period 1978-1990 (12.5 years), 929 neonatal general surgical emergencies were treated at the Seoul National University Children's Hospital. There were 308 anorectal malformations, 128 atresia/stenosis of the gut, 125 neonatal Hirschsprung's disease, 75 gastroschisis and 67 esophageal atresias. The highest o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90194-l
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:Previous studies using ultrasound technology showed that fetal heart rate (HR) may be responsive to maternal aerobic exercise. Although it is recognized that cardiac autonomic control may be influenced by the intrauterine environment, little is known about how maternal exercise affects fetal heart developmen...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.03.002
更新日期：2010-04-01 00:00:00
abstract：:We describe the managment of 2 sets of pre-term quadruplets born to 2 women pregnant concurrently following the induction of ovulation with gonadotrophin. Careful antenatal planning was necessary to provide for each of the 8 pre-term infants a standard of neonatal medical and nursing care comparable to that normally a...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(77)90028-7
更新日期：1977-10-01 00:00:00
abstract：:The purpose of this study was to investigate prostanoid synthesis in different segments of the umbilicoplacental vascular tree and its relationship to impaired maternal glucose tolerance. Segments from the umbilical artery and vein, allantochorionic artery branches, and the cotyledon artery from 21 women with diabetes...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3732(97)00036-2
更新日期：1998-01-09 00:00:00
abstract：:The evolution of ultrasound findings in 59 infants with transient periventricular densities is described and the neurodevelopmental outcome of 53 of these infants was compared with 92 of 107 infants with normal ultrasound scans, born during the same 24-month period. Four of the 53 infants with transient periventricula...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(88)90103-x
更新日期：1988-03-01 00:00:00
abstract：OBJECTIVE:In the general framework of relating birthing events to later mental development, this study addresses the hypothesis that uneventful non-vertex delivery is associated with higher intelligence than uneventful vertex delivery. STUDY DESIGN:In the course of a developmental obstetrical survey, data was gathered...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90065-5
更新日期：1994-09-30 00:00:00
abstract：:Pulse oximetry screening is a highly specific, moderately sensitive test for detecting critical congenital heart defects (CCHDs) that meets the criteria for universal screening. The possibility of using pulse oximetry as a screening test was first investigated over 10 years ago and since then data from more than 370,0...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)50006-0
更新日期：2014-09-01 00:00:00
abstract：:More than 10,000 preterm babies worldwide have been enrolled in trials evaluating probiotics administration for the prevention of necrotising enterocolitis, with very few adverse events reported. Despite this, probiotic safety is frequently cited as a concern when using this intervention. This review addresses why a p...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2019.05.016
更新日期：2019-08-01 00:00:00
abstract：:This century has seen marked improvement in perinatal outcomes but prematurity remains a problem the world over. To improve these results requires more attention to early pregnancy or even pre-pregnancy care. Control of pre-existing conditions, improved social behavior in nutrition, smoking cessation and other factors...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90064-n
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:To date, no study has compared preterm and full term auditory environments. AIM:To define differences in auditory exposure for preterm infants at term equivalent age in the neonatal intensive care unit (NICU) compared to auditory exposure in hospital rooms on a labor and delivery ward after full term birth....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.07.001
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the preschool neurodevelopmental outcome in CDH survivors between 2 and 5 years of age and to identify perinatal and postnatal factors that may be predictive of persistent neurological deficits. METHODS:The study cohort consists of 60 CDH survivors that were enrolled in our prospective, follow-up...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.12.009
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:Preterm infants have a high risk of cranial deformity resulting from external pressures. Such deformity is associated with delayed neurodevelopment. AIMS:We aimed to clarify the effects of continuous use of positioning pillows on cranial deformity and neurodevelopment in preterm infants. METHODS:This prosp...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105137
更新日期：2020-09-01 00:00:00
abstract：:Fifty-five pregnant Rhesus isoimmunized women were subjected to fetal blood sampling or fetal blood transfusion on 135 occasions. Glucose and C-peptide concentrations were measured in fetal blood, in addition to the routine investigations for complete blood count, blood gases and lactate concentration, in order to inv...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90027-g
更新日期：1990-12-01 00:00:00
abstract：OBJECTIVE:A short course of moderately early dexamethasone therapy with a starting dose of 0.5 mg/kg/day improves lung compliance and shortens the duration of ventilatory support in preterm infants with respiratory distress syndrome (RDS). We conducted a double-blind, randomized study to evaluate whether a moderately e...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0378-3782(03)00082-3
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVE:Maternal smoking during pregnancy is associated with a reduction in birth size but very few studies have collated changes in neonatal anthropometry. Our aims were both to assess body composition differences by anthropometry between new-borns from smoking mothers and those from non-smoking mothers, and to show...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.07.015
更新日期：2012-03-01 00:00:00
abstract：:The fatty acid content of fetal tissues was utilized to estimate essential fatty acid accretion during intrauterine growth. These rates of essential fatty acid accretion were used to predict that 400 mg/kg of body weight for omega-6 fatty acids and 50 mg/kg of body weight for omega-3 fatty acids per day would be used ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(81)90016-5
更新日期：1981-09-01 00:00:00
abstract：:The worst of institutional care was brought to public attention in Romania during the 1990s when pictures of severely deprived and malnourished children were shown around the world. However, many European countries have high rates of young children in institutions, where the physical care of the child predominates, wi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.09.018
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. AIMS:To evaluate the effects of an early post-discharge d...
journal_title：Early human development
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.earlhumdev.2006.01.011
更新日期：2006-10-01 00:00:00
abstract：:Children born preterm are at risk for later developmental disorders. The present study examined the predictive effects of neonatal, sociodemographic, and temperament characteristics on behavioral outcomes at toddlerhood, in children born preterm. The sample included 100 toddlers born preterm and with very-low-birth-we...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.09.015
更新日期：2016-12-01 00:00:00
abstract：:A review of the conundrum called mild hypoxic-ischemic encephalopathy (HIE) is provided. During the past decades, the definition of HIE has evolved to accommodate the short window of time required for the initiation of therapeutic hypothermia. Also, neurological evaluations have changed with the use of simpler staging...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2018.02.008
更新日期：2018-05-01 00:00:00
abstract：:The essential fatty acid (EFA) composition of umbilical vessel walls is increasingly being studied as a longer-term reflection of the fetal EFA status. We evaluated the EFA content of umbilical artery and vein vessel walls in 43 preterm infants and compared it with that of 43 full-term cord vessels. In addition, relat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01656-n
更新日期：1995-08-18 00:00:00
abstract：BACKGROUND:Even though the biological norm in humans is frequent on demand breastfeeding, sparse feeding intervals have become the cultural norm in most Western countries due to a history of on schedule breastfeeding. This discrepancy between the biological basis and the culturally driven practice continues to interfer...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105242
更新日期：2020-12-01 00:00:00
abstract：:Prevention of extra-uterine growth retardation is of extreme importance, as the achievement of adequate growth has been associated with a favorable neurodevelopmental outcome through childhood. In addition, as disturbances in growth that take place early in life may affect adult health, a full understanding of the gro...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.08.004
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Human milk contains a range of host defence proteins that appear to contribute to health and wellbeing, but their variability in abundance among individuals has not been very well characterised. Milk from mothers of premature infants has altered composition, but the effect of gestation length on the host-def...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.11.006
更新日期：2015-01-01 00:00:00
abstract：:Doctors are frequently depicted as important protagonists in science fiction, including in the science fiction franchise Star Trek. This paper will profile Drs. Philip Boyce and Mark Piper from the first two Star Trek pilot episodes. These doctors are interdisciplinarians with a variety of skills that permit them to c...
journal_title：Early human development
pub_type： 杂志文章,实务指引
doi：10.1016/j.earlhumdev.2020.104988
更新日期：2020-05-01 00:00:00
