Abstract：
BACKGROUND:In severe intrauterine growth restriction (IUGR) due to placental insufficiency a haemodynamic adaptation occurs, resulting in preferential blood flow to the fetal brain (brain sparing). With Doppler ultrasound an increased ratio between the umbilical and the cerebral artery pulsatility index (U/C ratio) can be demonstrated. IUGR is associated with impaired neurodevelopmental outcome.
OBJECTIVE:Evaluation of the effect of fetal brain sparing on behavioural problems at eleven years in premature born children.
METHODS:Prospective cohort study in premature children born in 1989, with a gestational age of 26 0/7 to 33 0/7 weeks. An U/C ratio>0.72 was defined as brain sparing. Behavioural problems were assessed with the parent-reported Child Behaviour Check List (CBCL) and the Teacher's Report Form (TRF). T scores >60 for total problem score and subscales of internalizing and externalizing behaviour, were considered abnormal.
RESULTS:Ninety-eight of the 116 survivors were assessed, of which 31 with antenatally established fetal brain sparing. According to the CBCL-total problem score 23.3% of the premature born babies in the brain sparing group had behavioural problems compared with 22.8% of those without brain sparing. According to the TRF-total problem score the percentages were 21.4% and 20.0%, respectively. Logistic regression analysis failed to show a significant association of U/C ratio with behavioural problems. In this model oxygen dependency at 28 days, IQ<85 at five years, cranial ultrasound abnormalities, fetal growth ratio<0.80, Apgar scores<7 after 5 min and birth weight journal_name journal_title authors doi subject pub_date pages issue eissn issn pii journal_volume pub_type
abstract：:Several guidelines have been created in an attempt to raise the quality of different kinds of studies. These also attempt to ensure that research is reported accurately and transparently. Six such guidelines (CONSORT, MOOSE, PRISMA, SPIRIT, STARD, and STROBE) will be briefly discussed in this paper. The purpose of the...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.05.014
更新日期：2019-07-01 00:00:00
abstract：:One hundred consecutive cranial computed tomographic scans were reviewed in children aged 0-2 years, presenting to the Royal Belfast Hospital for Sick Children. The mean age at scanning was 8.3 months and 73% of the scans were abnormal. The majority of scans were performed electively (78%). The commonest indication fo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(91)90011-q
更新日期：1991-08-01 00:00:00
abstract：:A management programme for the control and treatment of Rh0 (D) immunized during pregnancy is presented. A total of 34,650 births were registered during a 4.5 year period and included 63 D positive newborns to D-immunized mothers. The outcome of all infants has been evaluated according to the severity of the haemolyti...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(87)90096-x
更新日期：1987-01-01 00:00:00
abstract：:Surfactant is now available for general clinical use in infants with RDS. While surfactant is effective, it does not prevent lung disease in many preterm infants because of other aspects of lung immaturity. In experimental models, corticosteroids alter the fetal lung by improving compliances, increasing lung volumes, ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/0378-3782(92)90058-o
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:It remains unclear whether performing amniocentesis to detect intra-amniotic infection is useful for improving neonatal outcomes. AIMS:To determine the efficacy of amniocentesis on the neonatal outcomes in women exhibiting threatened preterm labor and intact membranes. STUDY DESIGN:Retrospective cohort stu...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.03.006
更新日期：2015-05-01 00:00:00
abstract：:Slide show presentations have become integral to the workplace, and PowerPoint is ubiquitous since it ships with the Microsoft Office Suite. However, the increasing sophistication of such software may encourage presenters to privilege form over content. It is possible to apply scientific research from Educational Psyc...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.06.006
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Placental pathology is associated with long-term neurological morbidity. Little is known about the association of placental pathology and illness severity directly after birth in preterm infants. OBJECTIVE:To determine the association between placental pathology and illness severity in preterm infants durin...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.01.040
更新日期：2011-04-01 00:00:00
abstract：:The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alt...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90186-6
更新日期：1986-12-01 00:00:00
abstract：:Maturation of spontaneous fetal body and breathing movements of 24- to 33-week-old fetuses in 168 pregnancies threatening to deliver prematurely were examined on the basis of newborn outcome (premature compromised, premature healthy, term healthy). Maturation of fetuses in 60 low-risk pregnancies delivering as healthy...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00007-9
更新日期：1999-05-01 00:00:00
abstract：:The effect of type-I diabetes on the quality of general movements (GMs) was studied longitudinally in 12 human fetuses. GMs were analysed at two-weekly intervals from 16 weeks until delivery. A pregnancy optimality-score and a diabetes optimality-score were used to cover the course of the pregnancy and delivery and th...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)00089-3
更新日期：1997-11-24 00:00:00
abstract：:Several studies have described an association between very preterm birth and behavioral and psychiatric outcomes in childhood and adolescence. The exact mechanisms underlying this association are unknown, but impaired neurodevelopment has been proposed as a possible etiological factor. Existing research suggests a sel...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.02.002
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:We evaluated the effect of maternal administration of betamethasone (0.2 mg/kg per day) on mitogen-induced lymphocyte proliferation and interleukin-2 (IL-2) production by maternal, fetal, and neonatal rat splenic lymphocytes. STUDY DESIGN:Betamethasone was injected intramuscularly on days 19 and 20 of gestat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90028-0
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:Positional plagiocephaly refers to atypical development of an uneven head shape with asymmetrical head orientation as a post-natal risk factor. The development of the head orientation profile and its relationship with positional plagiocephaly are lacking. OBJECTIVES:To explore the head orientation profile d...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.03.001
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVES:To determine whether early mortality (first year of life) risks among small for gestational age (SGA) neonates were similar regardless of SGA subtype based on three chronological classifications (term, preterm and post-term). STUDY DESIGN:Retrospective cohort study on all singleton live births in the United...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.05.008
更新日期：2007-02-01 00:00:00
abstract：:Son preference remains common in countries from East Asia through South Asia to the Middle East and North Africa. Where sex selective technology and abortion are readily available, such as in China, South Korea and India, this has led to a marked excess in male births. Worst excesses are seen in parts of rural China w...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.08.016
更新日期：2011-11-01 00:00:00
abstract：AIMS:To study longitudinal growth pattern of head circumference of full-term symmetric and asymmetric small for gestational age (SGA) infants of the two sexes during first year of life. STUDY DESIGN:Mixed-longitudinal growth research design. SUBJECTS:Head circumference amongst full-term 100 symmetric, 100 asymmetric ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.11.007
更新日期：2012-07-01 00:00:00
abstract：BACKGROUND:There is a lack of standardized echocardiographic parameters to quantify ventricular function in newborn infants. Long-axis systolic ventricular shortening is a useful parameter of global ventricular function. AIMS:Serial assessment of long-axis systolic atrioventricular annulus excursion in premature infan...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.09.006
更新日期：2013-12-01 00:00:00
abstract：INTRODUCTION:Children born very preterm (VPT) are at increased risk of emotional and behavioral problems later in life. We aimed to determine the prevalence and spectrum of behavioral abnormalities at five years of age in VPT children. METHODS:Multi-center cohort study on 339 early-school aged children born at a gesta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105200
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Children born preterm are known to be at risk for neurodevelopmental disorders. The role of perinatal asphyxia in this increased risk is still a matter of debate. AIM:To analyze the contribution of perinatal asphyxia in a population of preterm infants admitted to a secondary paediatric setting to neurologic...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.06.003
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Movement by an infant during the first year of life might influence its activity level and thereby influence growth in early childhood. AIM:To examine whether the time that an infant is able to move unrestrictedly and time spent in baby seats are related to weight and waist circumference at age 9 months and...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.04.002
更新日期：2013-07-01 00:00:00
abstract：:There is a wide differential diagnosis of early onset respiratory distress especially in term babies, and interstitial lung disease (chILD) is a rare but important consideration in this context. chILD manifesting immediately after birth is usually related to mutations in surfactant protein genes, or conditions related...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105186
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:There is concern that exposure of preterm infants to noxious insults over a prolonged period may have long term effects on their developing nervous system. AIMS:To investigate medium and long term effects of heel pricks in infants over the first year of life. STUDY DESIGN:Study 1-a longitudinal study, 2 da...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.09.018
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Previously, we reported that regular maternal aerobic exercise during pregnancy was associated with lower fetal heart rate (HR) and higher heart rate variability (HRV) at 36weeks gestation. We now report the effect of maternal exercise on infant HR and HRV in subjects who remained active in the study at the ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.11.001
更新日期：2014-01-01 00:00:00
abstract：:Breast- and formula-fed infants were compared with regard to behavior patterns, especially crying behavior. A diary concerning seven behaviors was completed by 188 mothers of breast- and formula-fed infants at the well baby clinic. Breast-fed infants were fed more frequently with longer feeding duration. They slept mo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(00)00071-2
更新日期：2000-05-01 00:00:00
abstract：:We measured plasma and erythrocyte vitamin E (VE) and plasma vitamin A (VA) profiles in 48 full-term and 8 preterm pairs of neonates and their mothers at birth and we determined whether there is any relationship between maternal and umbilical cord for the nutrients measured. At the same time, we assessed the influence...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00070-x
更新日期：1998-12-01 00:00:00
abstract：:In planning enteral feeding in the preterm infant, decisions need to be made regarding the feeding schedule, choice of milk, and the route of administration. Feeds should be commenced within a week after birth beginning with subnutritional quantities. Preterm human milk from the infant's own mother is the milk of choi...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(99)00047-x
更新日期：1999-12-01 00:00:00
abstract：:Fetal bladder volume and hourly fetal urine production (HFUPR) is calculated on the assumption that the fetal bladder is ellipsoid in shape. A recent validation study demonstrated a progressive overestimation at increasing bladder volumes. This may be due to changes in shape of the fetal bladder at increasing volumes....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)00049-2
更新日期：1998-02-27 00:00:00
abstract：AIM:To compare the order and age of emergence of rolling prone to supine and supine to prone before the introduction of back to sleep guidelines and 20 years after their introduction. METHODS:The original normative data for the Alberta Infant Motor Scale (AIMS) were collected just prior to the introduction of back to ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.10.009
更新日期：2013-05-01 00:00:00
abstract：:COVID-19 remains pandemic. Social distancing and travel restrictions have avoided countless deaths and infections but disrupted livelihoods and economies. The global loss of gross (world) product is unprecedented as COVID-19 has inflicted both a supply-side and a demand-side shock. While public health measures have mi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105209
更新日期：2020-10-01 00:00:00
abstract：:Measurement of methionine levels in dried blood spots has been one of the items of neonatal screening in Taiwan for more than 20 years. In 1,701,591 newborns, 17 cases of hypermethioninemia were detected, but among them only one had homocystinuria. More than half of the 16 cases of isolated hypermethioninemia had muta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2004.11.005
更新日期：2005-06-01 00:00:00
