Abstract:
:Surfactant is now available for general clinical use in infants with RDS. While surfactant is effective, it does not prevent lung disease in many preterm infants because of other aspects of lung immaturity. In experimental models, corticosteroids alter the fetal lung by improving compliances, increasing lung volumes, decreasing pulmonary edema, and altering surfactant-compliance dose response curves. These effects are independent of changes in surfactant pools but augment the responses of the lungs to surfactant treatment. Optimal outcomes for the preterm require the combined use of fetal maturation strategies and postnatal surfactant.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Jobe AHdoi
10.1016/0378-3782(92)90058-okeywords:
subject
Has Abstractpub_date
1992-06-01 00:00:00pages
57-62issue
1-3eissn
0378-3782issn
1872-6232pii
0378-3782(92)90058-Ojournal_volume
29pub_type
杂志文章,评审abstract:BACKGROUND:Pregnant women's sleep disturbance due to fetal movement is well known. Fetal movement is thought to be an index of fetal well-being. However, as there has never been a way to easily and reliably record fetal movement, psychophysiological studies of pregnant women's sleep disturbance and fetal well-being hav...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2008.03.001
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Intrauterine growth restriction (IUGR) is a fetal condition characterized by growth-rate reduction. Afflicted fetuses tend to display abnormalities in heart rate. OBJECTIVE:To study the differences in the heart-rate variability of low-risk fetuses and IUGR fetuses during different behavioral states. METHOD...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2013.07.002
更新日期:2013-10-01 00:00:00
abstract::The levels of growth hormone, vasopressin, prolactin, calcitonin, gastrin, insulin, epinephrine, norepinephrine and dopamine were measured in six lactating women during breast feeding. Prolactin levels increased in response to suckling as expected. In addition, insulin levels rose two-fold. No consistent changes were ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(84)90117-8
更新日期:1984-09-01 00:00:00
abstract:BACKGROUND:Children born preterm are at risk of visuospatial attention orienting and processing dysfunctions, which can be quantified early in life using visually-guided eye movement responses. AIMS:To identify the prevalence and perinatal risk factors for visuospatial attention orienting and processing dysfunctions i...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2019.01.015
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Controversial results have been reported on the effect of type of feeding on the level of fecal calprotectin in infants. OBJECTIVE:To assess fecal calprotectin levels in breast fed or nonbreast fed healthy infants. DESIGN:A study was conducted to compare fecal calprotectin in infants who were exclusively b...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.06.005
更新日期:2014-09-01 00:00:00
abstract::A fetus with signs of hydrops is at high risk of intrauterine death. The pathophysiology of hydrops fetalis is still unclear. We found decreased concentrations of cyclic guanosine monophosphate in fetal plasma of alloimmunized pregnancies complicated by hydrops fetalis, which might suggest reduced nitric oxide product...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(99)00063-8
更新日期:2000-03-01 00:00:00
abstract::Fourteen infants of 2 months or 6 months of age were video-recorded during polysomnography. Four were normal infants, five had a history of ALTE (apparent life threatening event) and five had repeated and prolonged apnoea during sleep. Two ALTE infants have been recorded at 2 months as well as at 6 months of age. Move...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90098-1
更新日期:1994-12-16 00:00:00
abstract:BACKGROUND:Prior studies have shown that children with congenital hearing loss have increased rates of behavior disorders. Child hearing loss has also been reported to be associated with increased maternal stress. Little is known about the behavior or the predictors of behavioral outcomes of children with hearing loss ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.06.006
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Despite its prevalence and potential maternal and neonatal implications, the literature on the thickness levels of meconium stained amniotic fluid (MSAF) and its impact on neonatal outcomes is relatively outdated and relies on relatively small sample sizes. AIMS:To study if different thickness levels of MSA...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.104953
更新日期:2020-03-01 00:00:00
abstract::The relationship between the traction forces used in 53 clinically indicated vacuum extractions and the incidence and degree of retinal hemorrhages observed in the neonates within 24 hours after birth was examined. A Vacuum Extractor Recorder (Type SF 30, Knick), was used to measure the traction force necessary for de...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(88)90107-7
更新日期:1988-03-01 00:00:00
abstract:AIM:To determine whether maternal state and trait anxiety levels affect fetal movements or fetal heart rate (FHR) in the third trimester. SUBJECTS:Forty-one healthy pregnant nulliparous women not on medication and with a singleton pregnancy. STUDY DESIGN:Maternal anxiety was assessed using the Spielberger State- Trai...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(01)00256-0
更新日期:2002-04-01 00:00:00
abstract::gamma-Aminobutyric acid (GABA) concentrations in cerebrospinal fluid (CSF) were measured in 20 neonates with various gestational and postnatal ages. These concentrations varied between 9 and 45 nmol/ml which is approximately 20-100 times the concentrations found in adults. CSF GABA concentrations tended to decrease wi...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(82)90007-x
更新日期:1982-10-01 00:00:00
abstract::The transitional circulation of the preterm infant differs significantly from the term infant. The preterm infant is uniquely at risk of hypotension and low systemic blood flow states due to failure or delay in the normal transitional circulation processes. The maintenance of normal tissue oxygenation requires mainten...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2005.03.006
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:The importance of an infant's intra-oral vacuum in milk removal from the breast has been established. However, the relationship between the vacuum curve and milk transfer is not well understood. AIMS:To investigate the parameters of the infant suck cycle in relation to the volume of milk removed from the br...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.02.003
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Preterm children are at risk for executive function (EF) problems, which have been linked to behavior and learning problems in full term children. In this study, we examine the relationship between EF and functional outcomes in preterm children. AIM:To evaluate (1) EF skills of 9- to 16-year-old children bo...
journal_title:Early human development
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.earlhumdev.2011.07.018
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:An increased risk of major congenital abnormalities after IVF and ICSI has been described, but underlying mechanisms are unclear. This study evaluates the effects of ovarian hyperstimulation, the in vitro procedure and time to pregnancy (TTP) - as proxy for the severity of subfertility - on the prevalence of...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.06.002
更新日期:2012-10-01 00:00:00
abstract::Twenty-eight very low birth weight (VLBW) and 32 full term infants were prospectively assessed at one year of age for hearing, language development and neurological status. The prevalence of conductive hearing deficits was the same in both groups. Language scores in VLBW infants were significantly lower than in fullte...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(90)90007-6
更新日期:1990-10-01 00:00:00
abstract::A review of the conundrum called mild hypoxic-ischemic encephalopathy (HIE) is provided. During the past decades, the definition of HIE has evolved to accommodate the short window of time required for the initiation of therapeutic hypothermia. Also, neurological evaluations have changed with the use of simpler staging...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2018.02.008
更新日期:2018-05-01 00:00:00
abstract::The possibility of assembling this series of Best Practice Guidelines papers pertaining to WASP (Write a Scientific Paper) arose from the international WASP course, and the realisation that the Statistics at Square One papers initially published in the British Medical Journal in the 1970s, dealing with medical statist...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2019.05.012
更新日期:2019-07-01 00:00:00
abstract:INTRODUCTION:Survivors of congenital diaphragmatic hernia have increased with the introduction of new treatment modalities and have been reported to experience ongoing medical morbidity until adulthood. AIM:To describe the long-term functional impact of congenital diaphragmatic repair on the survivors of a single inst...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.08.025
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Animal experiments have convincingly demonstrated that prenatal maternal stress affects pregnancy outcome and results in early programming of brain functions with permanent changes in neuroendocrine regulation and behaviour in offspring. AIM:To evaluate the existing evidence of comparable effects of prenata...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/s0378-3782(02)00075-0
更新日期:2002-12-01 00:00:00
abstract::In the face of evidence of human milk contamination by organochlorine pesticides, an analysis was performed on samples of milk obtained from healthy lactating women in the provinces of Granada and Almeria in Southern Spain. The samples were obtained by the Neonate Section of the Department of Pediatrics of Granada Uni...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(01)00221-3
更新日期:2001-11-01 00:00:00
abstract::Intrauterine growth restriction (IUGR) is associated with altered lung development in human and rat. The transcription factor PPARγ, is thought to contribute to lung development. PPARγ is activated by docosahexanoic acid (DHA). One contribution of PPARγ to lung development may be its direct regulation of chromatin mod...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.08.026
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Respiratory syncytial virus (RSV) is a leading cause of hospitalization for children <1year old and is more severe in premature infants. OBJECTIVE:To assess whether late preterm (LPT) birth is an independent risk factor for RSV hospitalization and more severe RSV disease in children less than 24months old. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.06.009
更新日期:2015-09-01 00:00:00
abstract::The validity of the Wigglesworth experimental model to produce newborn rats that are small for gestational age by ligation of one of both uterine vessels was confirmed. Newborn rats from the opposite horns are used as controls in the classical model. It is concluded from this study that newborns from sham-operated dam...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(79)90038-0
更新日期:1979-09-01 00:00:00
abstract::Vascular tumours (haemangiomas and malformations) are common tumours of infancy and childhood. They represent a group of mostly benign conditions, which present early, can grow rapidly and be symptomatic or disfiguring. There are various management options, with different cosmetic and functional outcomes. Haemangiomas...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.08.017
更新日期:2010-10-01 00:00:00
abstract::Eleven healthy fetuses between 36 and 39 weeks of gestation were studied during the active sleep state to examine effects of a 5-s vibratory acoustic stimulus on the baseline fetal heart rate and flow velocity waveform in the fetal internal carotid artery. There was an immediate marked rise in baseline fetal heart rat...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(89)90105-9
更新日期:1989-04-01 00:00:00
abstract::We measured plasma and erythrocyte vitamin E (VE) and plasma vitamin A (VA) profiles in 48 full-term and 8 preterm pairs of neonates and their mothers at birth and we determined whether there is any relationship between maternal and umbilical cord for the nutrients measured. At the same time, we assessed the influence...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(98)00070-x
更新日期:1998-12-01 00:00:00
abstract::Standards for Research (StaR) in Child Health, founded in 2009, addresses the current scarcity of and deficiencies in pediatric clinical trials. StaR Child Health brings together leading international experts devoted to developing practical, evidence-based standards to enrich the reliability and relevance of pediatric...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2013.09.011
更新日期:2013-11-01 00:00:00
abstract::Unexpected death in infancy may be a consequence of recognisable pathophysiological processes, or may remain unexplained after thorough investigation. We review the appropriate investigations that should be performed after unexpected infant deaths, and the recent changes to UK law that will make such investigations ma...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2006.09.012
更新日期:2006-12-01 00:00:00