Abstract：
:COVID-19 remains pandemic. Social distancing and travel restrictions have avoided countless deaths and infections but disrupted livelihoods and economies. The global loss of gross (world) product is unprecedented as COVID-19 has inflicted both a supply-side and a demand-side shock. While public health measures have mitigated morbidity and mortality, the excessive loss of GDP will lead to years of life lost due to recession with diminished spend on healthcare, safety and the environment. This paper will review the estimated COVID-19 economic impact and show that it is timely and crucial to (carefully) ease restrictions as any additional economic slide will continue to intensify an already parlous situation and further negatively impact overall global average human life expectancy. The USA and UK will be used as specific examples, as will the general case of delayed cancer treatment due to COVID-19 service disruption. Financial stimuli that attempt to revive flagging economies by governments and blocs will be outlined and the current uniformly bleak global forecasts will be briefly contrasted with the Great Depression of the 1930s. The biased adverse impact on low-income households will be sketched, and a reminder of the unknown eventual costs of lasting illness ("long COVID") will also have to be factored in restriction removal policies. At this point in time (end of summer 2020), fierce debates rage within each country regarding the potential trade-offs of health vs economy. The need for unbiased and rigorous quantitative evaluations of all possible decisions is paramount.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Grech V,Grech Pdoi
10.1016/j.earlhumdev.2020.105209subject
Has Abstractpub_date
2020-10-01 00:00:00pages
105209eissn
0378-3782issn
1872-6232pii
S0378-3782(20)30693-9pub_type
杂志文章abstract：:Apnea of prematurity and gastroesophageal reflux (GER) are both common occurrences in preterm infants and widely perceived to be causally related. We seek in this review to provide a potential guideline for neonatal GER non-pharmacologic and pharmacologic therapy. Available physiologic data suggest that when there is ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(13)70005-7
更新日期：2013-06-01 00:00:00
abstract：INTRODUCTION:Many women with a bipolar disorder are of reproductive age and will need to continue lithium treatment during pregnancy. The teratogenic and perinatal effects of lithium are known, but not the long-term effects of lithium on neurodevelopment of the children. This study investigates growth, neurological, co...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.09.013
更新日期：2012-06-01 00:00:00
abstract：:Adrenocortical response to stress in neonates was assessed by estimating salivary concentrations of cortisol, dehydroepiandrosterone (DHEA) and dehydroepiandrosterone-sulfate (DHEA-S). Behavioral responses to stress were also scored clinically, according to the method of Lewis and Thomas [15]. The modulation of these ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(96)01749-5
更新日期：1996-09-20 00:00:00
abstract：:Lung surfactant was obtained by postmortem lavage from: (A) premature babies: 34 dying acutely within 2 days of birth from Hyaline Membrane Disease (HMD), 20 dying several days after birth with HMD and its consequences, 8 dying from causes other than HMD; (B) mature babies: 24 dying stillborn, 15 dying soon after birt...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(88)90094-1
更新日期：1988-03-01 00:00:00
abstract：BACKGROUND:The entorhinal cortex serves as an important gateway between the cerebral cortex and the hippocampus by receiving afferent information from limbic, modality sensory-specific, and multimodal association fibers from all the brain lobes. AIM:To investigate whether thinning of entorhinal cortex is associated wi...
journal_title：Early human development
pub_type： 临床试验,杂志文章
doi：10.1016/j.earlhumdev.2011.07.017
更新日期：2012-02-01 00:00:00
abstract：AIM:The benefit of anti-reflux surgery for gastro-oesophageal reflux (GOR) in early infancy is uncertain. The aim of this study was to assess the value of Nissen fundoplication in a group of infants with severe GOR. METHODS:10 infants underwent Nissen fundoplication for gastro-oesophageal reflux following a failure of...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.09.002
更新日期：2003-12-01 00:00:00
abstract：:Given the widely acknowledged inverse relationship between birth weight and blood pressure, a raised blood pressure in the offspring of smoking mothers as compared to those whose mothers did not smoke, would be anticipated by virtue of the reduction in birth weight associated with smoking during pregnancy. The objecti...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00064-x
更新日期：2000-02-01 00:00:00
abstract：:The premature birth of a child and admission to the neonatal intensive care unit (NICU) is a distressing experience for parents, and has been associated with symptoms of depression, anxiety and post-traumatic stress. Supporting parents in the NICU after preterm birth is critical not only for their own mental health, b...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2019.104838
更新日期：2019-12-01 00:00:00
abstract：:As major sport events have been cancelled and postponed in response to COVID-19, the necessity to protect and provide a holistic approach to the professional athlete has never been greater. To do so one must understand the negative consequences for athletes in relation to the cancellation and postponement of such even...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105254
更新日期：2020-11-12 00:00:00
abstract：BACKGROUND:Placental pathology is associated with long-term neurological morbidity. Little is known about the association of placental pathology and illness severity directly after birth in preterm infants. OBJECTIVE:To determine the association between placental pathology and illness severity in preterm infants durin...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.01.040
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:Prior studies have shown that children with congenital hearing loss have increased rates of behavior disorders. Child hearing loss has also been reported to be associated with increased maternal stress. Little is known about the behavior or the predictors of behavioral outcomes of children with hearing loss ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.06.006
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Children born preterm are at risk of visuospatial attention orienting and processing dysfunctions, which can be quantified early in life using visually-guided eye movement responses. AIMS:To identify the prevalence and perinatal risk factors for visuospatial attention orienting and processing dysfunctions i...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.01.015
更新日期：2019-03-01 00:00:00
abstract：UNLABELLED:While the role of antiepileptic drug (AED) therapy in teratogenesis has widely been investigated, there are few prospective studies on later postnatal development in offspring of epileptic women in utero exposed. The aim of this study was a prospective investigation of the psychomotor development in a select...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(03)00083-5
更新日期：2003-11-01 00:00:00
abstract：:This century has seen marked improvement in perinatal outcomes but prematurity remains a problem the world over. To improve these results requires more attention to early pregnancy or even pre-pregnancy care. Control of pre-existing conditions, improved social behavior in nutrition, smoking cessation and other factors...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90064-n
更新日期：1992-06-01 00:00:00
abstract：:The potential use of a piglet as a model for investigation of brain blood flow was evaluated by assessing the presence of autoregulation in 11 spontaneously breathing newborn piglets. Blood pressure was altered by phlebotomy. When the mean arterial blood pressure was greater than 50 mm Hg, no significant change in bra...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(82)90063-9
更新日期：1982-01-01 00:00:00
abstract：:Six month infant-mother interaction patterns were observed and 10 month Bayley MDI scores were obtained in 10 fullterm and 14 healthy preterm (less than 37 weeks) infants. Relationships among interaction parameters and intellectual performance are compared with those among earlier interaction patterns and development....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90008-3
更新日期：1986-04-01 00:00:00
abstract：:It is convenient to calculate milk energy from the creamatocrit but in order to assess the accuracy with which energy content can be predicted in this way, the creamatocrit, the percentage of carbon, and the calorie value of milk were determined in 11 samples of pooled pasteurised human milk. The calculated milk energ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90121-5
更新日期：1985-05-01 00:00:00
abstract：BACKGROUND:Some researchers have developed child feeding indices to summarize child feeding practices so that they can compare child feeding practices across countries and monitor changes over time within a given country. AIMS:An adapted version of the infant and child feeding index (ICFI) developed by Ruel and Menon ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.10.009
更新日期：2009-04-01 00:00:00
abstract：:The aim of the study was to evaluate potential changes of cerebral blood volume (CBV) related to arousals in preterm infants. As arousals are known to change different physiological parameters, it was postulated that this could also hold true for CBV. Polygraphic recordings were performed in 38 preterm infants (18 fem...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.05.019
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the preschool neurodevelopmental outcome in CDH survivors between 2 and 5 years of age and to identify perinatal and postnatal factors that may be predictive of persistent neurological deficits. METHODS:The study cohort consists of 60 CDH survivors that were enrolled in our prospective, follow-up...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.12.009
更新日期：2013-06-01 00:00:00
abstract：:Studies in encephalopathic infants have demonstrated a brief phase of normal cerebral energetics following hypoxia-ischaemia prior to development of delayed energy failure. In experimental models, mild hypothermia has shown a consistent neuroprotective action, although its efficacy is critically dependent on the sever...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2004.10.014
更新日期：2005-01-01 00:00:00
abstract：:We have investigated infant-caregiver interactions in an isolated African subsistence farming community where women perform arduous agricultural tasks in addition to their normal domestic duties which include child care. 49 babies aged 3-18 months were studied on one or two occasions. Detailed observations were made o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90139-2
更新日期：1985-10-01 00:00:00
abstract：:Meconium aspiration syndrome (MAS) is a common neonatal problem and, sadly, results in acute and chronic respiratory morbidity. Although meconium aspiration can occur prior to delivery even in the absence of labour, in many infants this condition could be prevented by appropriate suctioning at birth. More accurate pre...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/0378-3782(95)01625-d
更新日期：1995-04-28 00:00:00
abstract：:The purpose of this study was to investigate prostanoid synthesis in different segments of the umbilicoplacental vascular tree and its relationship to impaired maternal glucose tolerance. Segments from the umbilical artery and vein, allantochorionic artery branches, and the cotyledon artery from 21 women with diabetes...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3732(97)00036-2
更新日期：1998-01-09 00:00:00
abstract：OBJECTIVE:To 1) define predictors of parent presence, any holding, holding in arms, and skin-to-skin care in the NICU and 2) investigate the relationships between parent participation and a) early neurobehavior and b) developmental outcomes at age 4 to 5years among preterm infants. METHODS:Eighty-one preterm infants b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.12.008
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:The reported national case fatality rates (CFRs) for coronavirus disease 2019 (COVID-19) shows a sex bias with males > females. The relative lengths of the index (2D) and ring (4D) fingers (digit ratio; 2D:4D) is a sexually dimorphic (males < females) proxy of fetal sex steroids (low 2D:4D indicates high pre...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105074
更新日期：2020-07-01 00:00:00
abstract：:In planning enteral feeding in the preterm infant, decisions need to be made regarding the feeding schedule, choice of milk, and the route of administration. Feeds should be commenced within a week after birth beginning with subnutritional quantities. Preterm human milk from the infant's own mother is the milk of choi...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(99)00047-x
更新日期：1999-12-01 00:00:00
abstract：:Little is known about thrombopoietin (Tpo) production in human fetuses and neonates. As a step toward determining whether Tpo is relevant to platelet production in the fetus and neonate, we hypothesized that: (1) like other cytokines, Tpo is present in the cord blood in higher concentrations than in adult plasma; (2) ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00077-2
更新日期：1999-01-01 00:00:00
abstract：:A management programme for the control and treatment of Rh0 (D) immunized during pregnancy is presented. A total of 34,650 births were registered during a 4.5 year period and included 63 D positive newborns to D-immunized mothers. The outcome of all infants has been evaluated according to the severity of the haemolyti...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(87)90096-x
更新日期：1987-01-01 00:00:00
abstract：:A review of the conundrum called mild hypoxic-ischemic encephalopathy (HIE) is provided. During the past decades, the definition of HIE has evolved to accommodate the short window of time required for the initiation of therapeutic hypothermia. Also, neurological evaluations have changed with the use of simpler staging...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2018.02.008
更新日期：2018-05-01 00:00:00
