Abstract：
:The aim of the study was to evaluate potential changes of cerebral blood volume (CBV) related to arousals in preterm infants. As arousals are known to change different physiological parameters, it was postulated that this could also hold true for CBV. Polygraphic recordings were performed in 38 preterm infants (18 female, 20 male). The infants' gestational age at birth was 32.0+/-2.3 weeks, postconceptional age was 35.1+/-1.2 weeks and postnatal age at study entry was 24.3+/-2.9 days, birth weight was 1793+/-527 g and actual weight at study entry was 2011+/-324 g [mean (+/- standard deviation)]. CBV was measured using near infrared spectroscopy. Arousals were scored due to the guidelines of the "International Paediatric Work Group on Arousals" and categorized as either cortical (CA) or subcortical arousals (SCA). Altogether, 122 arousals (66 CA, 56 SCA) were scored. According to sleep stage, 77 arousals were analyzed in active sleep, 23 in quiet sleep and 22 in intermediate sleep. Mean duration of arousals was 8.8+/-0.3 s. CBV, cerebral vascular oxygenation and the balance between oxygen delivery and oxygen consumption remained constant during arousals in preterm infants. This was demonstrated for both CA and SCA and was independent of sleep stage, suggesting that the impact of arousals in stable preterm infants is too small to alter cerebral vascular autoregulation.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Zotter H,Urlesberger B,Kerbl R,Mueller W,Pichler G,Curzi-Dascalova Ldoi
10.1016/j.earlhumdev.2006.05.019subject
Has Abstractpub_date
2007-04-01 00:00:00pages
239-46issue
4eissn
0378-3782issn
1872-6232pii
S0378-3782(06)00165-4journal_volume
83pub_type
杂志文章abstract：OBJECTIVE:To assess patterns of nutritive sucking in very preterm infants ≤32 weeks of gestation. STUDY DESIGN:Very preterm infants who attained independent oral feeding were prospectively assessed with an instrumented feeding bottle that measures nutritive sucking. The primary outcome measure was nutritive sucking pe...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105044
更新日期：2020-07-01 00:00:00
abstract：:We have investigated 20 healthy full-term newborns between the 4th and the 6th day of life in standard conditions for laterality of arm movements, before and after introduction of a target. The durations of recording were: (a) 5 min continuously before target introduction; (b) five 1-min units during target presentati...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(89)90099-6
更新日期：1989-04-01 00:00:00
abstract：:The possibility of assembling this series of Best Practice Guidelines papers pertaining to WASP (Write a Scientific Paper) arose from the international WASP course, and the realisation that the Statistics at Square One papers initially published in the British Medical Journal in the 1970s, dealing with medical statist...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.05.012
更新日期：2019-07-01 00:00:00
abstract：:Cranial ultrasound is the most available and easily repeatable technique for imaging the neonatal brain. Its quality and diagnostic accuracy depend on various factors; the suitability of the ultrasound machine for neonatal cranial work, the use of optimal settings and probes, appropriate scanning protocols, the use of...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2006.09.018
更新日期：2006-12-01 00:00:00
abstract：:The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alt...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90186-6
更新日期：1986-12-01 00:00:00
abstract：:The aims of the study were (1) to replicate previous quantitative studies of motor activity in low-risk and high-risk preterm infants and (2) to apply a new method of systematic analysis of the qualitative characteristics of general movements in these two groups of infants. Sequential one-hour videorecordings of the u...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90013-9
更新日期：1990-09-01 00:00:00
abstract：BACKGROUND:There is concern that exposure of preterm infants to noxious insults over a prolonged period may have long term effects on their developing nervous system. AIMS:To investigate medium and long term effects of heel pricks in infants over the first year of life. STUDY DESIGN:Study 1-a longitudinal study, 2 da...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.09.018
更新日期：2008-06-01 00:00:00
abstract：:We have investigated infant-caregiver interactions in an isolated African subsistence farming community where women perform arduous agricultural tasks in addition to their normal domestic duties which include child care. 49 babies aged 3-18 months were studied on one or two occasions. Detailed observations were made o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90139-2
更新日期：1985-10-01 00:00:00
abstract：:Twenty appropriate (mean +/- S.D., gestational age (AGA): 29.9 +/- 1.5 weeks) and 15 small (GA: 34.6 +/- 2.4 weeks) for gestational age (SGA) very low birth weight infants fed banked mature human milk were studied until term for anthropometric parameters: midarm (MAC), chest (CC), head (HC) circumferences, triceps (TS...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(87)90051-x
更新日期：1987-09-01 00:00:00
abstract：OBJECTIVE:To compare paired antepartum fetal/maternal COHb ratios in whole blood from control and alloimmunized pregnancies and to examine the relationships between fetal and maternal COHb. METHODS:COHb levels were measured in paired fetal and maternal blood samples obtained at cordocentesis in 47 control and 16 Rh-al...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(00)00079-7
更新日期：2000-06-01 00:00:00
abstract：BACKGROUND:Hydatidiform mole is an abnormal pregnancy with over-proliferation of the placenta, which causes the dysfunction of placenta. Although more than 80% of hydatidiform moles are benign with good outcome, hydatidiform moles are associated with developing very early onset preeclampsia. However the association bet...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.02.008
更新日期：2013-08-01 00:00:00
abstract：:Posture and spontaneous motor patterns during the first days of life were studied in ten healthy fullterm infants by direct observation and videorecording. The aim of the study was to provide a description of motor and postural characteristics of normal newborns. The infants were recorded for 1 h on their first and fo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(89)90020-0
更新日期：1989-02-01 00:00:00
abstract：:The calculation of descriptive statistics after data collection provides researchers with an overview of the shape and nature of their datasets, along with basic descriptors, and may help identify true or incorrect outlier values. This exercise should always precede inferential statistics, when possible. This paper pr...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.02.015
更新日期：2018-03-01 00:00:00
abstract：AIM:To assess whether attrition rate influences outcome in the follow-up of very preterm infants. STUDY DESIGN:In a national follow-up study of infants born alive in 1983 in the Netherlands with a gestational age less than 32 weeks and/or a birth weight less than 1500 g, outcome was assessed separately for adolescents...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2005.07.006
更新日期：2005-11-01 00:00:00
abstract：:Abnormal hypertonia of the neck extensor muscles in newborns may be appreciated by observing spontaneous posture, evaluating resistance to repeated passive flexion of the head, and eliciting the head straightening reflexes. This sign correlates well with other signs of insult to the central nervous system. Of 1743 new...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(77)90019-6
更新日期：1977-10-01 00:00:00
abstract：BACKGROUND:The Baby Preparation and Worry Scale (Baby-PAWS) addresses expectant mothers' anticipatory worries regarding the transition to parenthood, focusing on practical concerns (i.e., ability to care for the infant, securing childcare, personal wellbeing, and partner involvement). AIMS:The present study describes ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105080
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND AND AIM:To investigate whether neonates with prenatally detected congenital heart defects (CHD) demonstrate cerebral abnormalities on early preoperative cranial ultrasound (CUS), compared to healthy neonates, and to measure brain structures to assess brain growth and development in both groups. STUDY DESIGN...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105097
更新日期：2020-09-01 00:00:00
abstract：:The relationship between cyclic 3',5'-adenosine monophosphate (cAMP) excretion and creatinine clearance, urinary phosphate excretion, and urinary osmolarity was studied under basal conditions in 29 babies of 28-40 weeks gestation, during the first few days of life. Urinary cAMP excretion was directly related to creati...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(84)90112-9
更新日期：1984-09-01 00:00:00
abstract：BACKGROUND:Higher parenting stress in mothers of children born very preterm may be in part a response to poorer neurobehavioral development, reflecting realistic concerns in addition to adaptation to the trauma of preterm delivery. To our knowledge, there are few longitudinal studies of parenting stress that have addre...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.01.030
更新日期：2011-04-01 00:00:00
abstract：:Fetal cardiac waveform intervals were assessed from fetal magnetocardiogram (FMCG) recordings taken from 59 pregnant women at 17-41 weeks gestation. Beyond 27 weeks' gestation PR and QRS intervals, measured from averaged waveforms, could be obtained from all subjects; however, prior to 21 weeks' gestation the success ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00100-5
更新日期：1999-04-01 00:00:00
abstract：:Ninety five placentae from normal term and 'normal' preterm pregnancies have been analysed by morphometry. The growth of the whole placenta, of the microscopic placental constituents and of the villous surface area has been measured in placentae from uncomplicated pregnancies from 10 weeks of gestation to term to prov...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(84)90074-4
更新日期：1984-06-01 00:00:00
abstract：:The relationship between the traction forces used in 53 clinically indicated vacuum extractions and the incidence and degree of retinal hemorrhages observed in the neonates within 24 hours after birth was examined. A Vacuum Extractor Recorder (Type SF 30, Knick), was used to measure the traction force necessary for de...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(88)90107-7
更新日期：1988-03-01 00:00:00
abstract：:The brain glycoconjugates, glycosidases and lipids have been studied in a case of human congenital athyroidism never treated with hormonal replacement. Increase of membrane-bound mucopolysaccharides has been found in the grey matter. Total lipids in the white matter, and phospholipids, and total glycolipids and choles...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90009-9
更新日期：1983-10-01 00:00:00
abstract：:Newborn infants, especially preterm infants, have an immature immune system, which is not capable to actively protect against vaccine-preventable infections. Therefore, the newborn is dependent on transplacental transport of Immunoglobulin G (IgG), an active, FcRn receptor mediated process. Fetal IgG rises from approx...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2010.11.003
更新日期：2011-02-01 00:00:00
abstract：:The relationship between blood glucose and body physique of 233 (42 hypo-and 191 normologycemic) intrauterine growth-retarded neonates was analyzed using different body measurements and indices of body proportions. Classification by combination of weight and length deficit for fetal age revealed that the disproportion...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(77)90027-5
更新日期：1977-10-01 00:00:00
abstract：BACKGROUND:To date, no study has compared preterm and full term auditory environments. AIM:To define differences in auditory exposure for preterm infants at term equivalent age in the neonatal intensive care unit (NICU) compared to auditory exposure in hospital rooms on a labor and delivery ward after full term birth....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.07.001
更新日期：2019-09-01 00:00:00
abstract：:In the last two decades the survival of extreme preterm infants and sick newborn infants has improved significantly due to the advances in perinatal medicine. Despite this advance, for some babies, withholding or withdrawal of life sustaining treatment may be the best option in the interest of the baby. An overview of...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2012.01.002
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:Fluconazole prophylaxis has demonstrated efficacy in single and multicenter randomized controlled trials without side effects or emergence of resistance. Additional evidence based on incidence of invasive Candida infections, multicenter data, resistance, and safety is desired. METHODS:We conducted a case-co...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0378-3782(14)70026-X
更新日期：2014-03-01 00:00:00
abstract：:The introduction of exchange transfusion made it possible to prevent severe hyperbilirubinemia and kernicterus, but kernicterus has never completely disappeared and it is still occurring in North America and, more frequently in Western Europe and the developing world. I discuss the epidemiology and major causes of sev...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2009.09.003
更新日期：2009-11-01 00:00:00
abstract：:We report a breast-fed preterm infant (31 weeks gestation) who developed nutritional zinc deficiency 13 weeks post delivery. Serial samples of his mothers breast milk from early lactation (2 weeks post delivery) contained very low zinc concentrations, although her serum zinc and sweat zinc concentrations were normal. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90062-3
更新日期：1985-01-01 00:00:00
