Abstract：
:Studies in encephalopathic infants have demonstrated a brief phase of normal cerebral energetics following hypoxia-ischaemia prior to development of delayed energy failure. In experimental models, mild hypothermia has shown a consistent neuroprotective action, although its efficacy is critically dependent on the severity of the primary insult, the delay in initiating cooling, and the duration and depth of hypothermia. Early electroencephalographic assessment of encephalopathic infants has the potential to provide objective information about the preceding insult, aiding the selection of infants for enrollment to clinical trials. Preliminary results from a large randomised trial of selective head cooling suggest that early intervention can lead to significantly improved outcome in a subgroup of encephalopathic infants with intermediate electroencephalographic abnormalities. Further research in established experimental models is essential to improve the identification of suitable infants for treatment, to investigate the importance of variations in regional brain temperature, and to examine the therapeutic potential of hypothermia combined with other neuroprotective agents.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Wyatt JS,Robertson NJdoi
10.1016/j.earlhumdev.2004.10.014keywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
5-11issue
1eissn
0378-3782issn
1872-6232pii
S0378-3782(04)00186-0journal_volume
81pub_type
杂志文章,评审abstract：:Interfacility transport to tertiary care for high-risk neonates has become an integral part of equitable access to optimal perinatal healthcare. Excellence in clinical care requires expertise in transport medicine and the coordination of safe transport processes. However, concerns remain regarding environmental stress...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2020.105051
更新日期：2020-07-01 00:00:00
abstract：:Several guidelines have been created in an attempt to raise the quality of different kinds of studies. These also attempt to ensure that research is reported accurately and transparently. Six such guidelines (CONSORT, MOOSE, PRISMA, SPIRIT, STARD, and STROBE) will be briefly discussed in this paper. The purpose of the...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.05.014
更新日期：2019-07-01 00:00:00
abstract：:Delayed emergence of movement patterns and disturbances in the development of behavioural states are often observed in the fetuses of diabetic women. The developmental course of specific fetal movement patterns was studied in 20 women with type-1 diabetes during the first trimester of pregnancy. The aim was to investi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(91)90190-e
更新日期：1991-05-01 00:00:00
abstract：OBJECTIVE:To compare measurements of the upper arm cross-sectional areas (total arm area, arm muscle area, and arm fat area of healthy neonates) as calculated using anthropometry with the values obtained by ultrasonography. MATERIALS AND METHODS:This study was performed on 60 consecutively born healthy neonates: gesta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00085-1
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:Using pure oxygen (PO) in neonatal resuscitation increases oxidative stress and mortality in full-term hypoxic infants. International neonatal resuscitation guidelines recommend air or blended oxygen for resuscitation regardless of gestational age but this requires education and equipment that may not be glo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.01.005
更新日期：2012-08-01 00:00:00
abstract：:The aim of the study was to evaluate potential changes of cerebral blood volume (CBV) related to arousals in preterm infants. As arousals are known to change different physiological parameters, it was postulated that this could also hold true for CBV. Polygraphic recordings were performed in 38 preterm infants (18 fem...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.05.019
更新日期：2007-04-01 00:00:00
abstract：:In the scholarly environment, research findings are disseminated as journal papers which support/dispute extant knowledge or add further to what is already known. The entire manuscript needs to be cited (in-text) and referenced (at the end of article), in order for readers to ascertain the validity of the research cla...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.09.012
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Intrauterine growth restriction (IUGR) is a fetal condition characterized by growth-rate reduction. Afflicted fetuses tend to display abnormalities in heart rate. OBJECTIVE:To study the differences in the heart-rate variability of low-risk fetuses and IUGR fetuses during different behavioral states. METHOD...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.07.002
更新日期：2013-10-01 00:00:00
abstract：:Fetal cardiac waveform intervals were assessed from fetal magnetocardiogram (FMCG) recordings taken from 59 pregnant women at 17-41 weeks gestation. Beyond 27 weeks' gestation PR and QRS intervals, measured from averaged waveforms, could be obtained from all subjects; however, prior to 21 weeks' gestation the success ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00100-5
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVE:To assess patterns of nutritive sucking in very preterm infants ≤32 weeks of gestation. STUDY DESIGN:Very preterm infants who attained independent oral feeding were prospectively assessed with an instrumented feeding bottle that measures nutritive sucking. The primary outcome measure was nutritive sucking pe...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105044
更新日期：2020-07-01 00:00:00
abstract：:The relationship between blood glucose and body physique of 233 (42 hypo-and 191 normologycemic) intrauterine growth-retarded neonates was analyzed using different body measurements and indices of body proportions. Classification by combination of weight and length deficit for fetal age revealed that the disproportion...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(77)90027-5
更新日期：1977-10-01 00:00:00
abstract：BACKGROUND:cardiac arrhythmias are commonly observed in the fetus, however, may have major consequences for fetal development and post natal life. AIMS:to evaluate the perinatal management and cardiac outcome of fetuses with tachy- or bradyarrhythmia. STUDY DESIGN:perinatal management, outcome and long-term cardiac f...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.11.001
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Previous studies suggest that RhD positive heterozygotes express better health status than RhD positive homozygotes and especially RhD negative subjects. This also applies to pregnant women. According to the Trivers-Willard hypothesis, women in better physical condition should have more sons. AIM:To test th...
journal_title：Early human development
pub_type： 杂志文章,实务指引
doi：10.1016/j.earlhumdev.2019.104864
更新日期：2020-01-01 00:00:00
abstract：AIMS:To determine the reproducibility and minimum detectable change (MDC) of heart rate variability (HRV) measures during two sequential 24-h periods, at week 32 of gestation, in preterm infants born between 28 and 32 weeks, hospitalized in the neonatal intensive care unit (NICU). The second aim is to assess postnatal ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105117
更新日期：2020-09-01 00:00:00
abstract：:Near infrared spectroscopy (NIRS) monitoring is a new challenge for clinicians who deal with early detection of dangerous hypoperfusion in the brain, as well as in splanchnic and renal districts in critically ill preterm infants. Previous studies performed on infants and children with congenital heart disease, demonst...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(13)70014-8
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND AND AIMS:The interaction between the infant and the caregiver is stated to be very important in the development of a child. When there is inadequacy of interaction, several emotional and developmental problems can emerge. We aimed to investigate the socio-demographic and clinical features of children diagnos...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.09.004
更新日期：2012-06-01 00:00:00
abstract：INTRODUCTION:The male-to-female ratio of live births is expressed as the ratio of male births divided by total births (M/F). Males are produced approximately 3% in excess. A large number of factors have been found to influence M/F. Stress and privation reduces M/F. Gender preference (which almost invariably favours mal...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.10.013
更新日期：2015-12-01 00:00:00
abstract：:221 small-for-dates (SFD) and 244 average-for-dates (AFD) children were personally examined at birth, and seen thereafter at regular intervals up to 4 years, when a thorough assessment was made. There was an excess of SFD children with major congenital abnormalities; but no difference between the groups in the number ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90007-5
更新日期：1983-10-01 00:00:00
abstract：:We studied the ontogeny and temporal organization of non-nutritive sucking during active sleep in 6 healthy preterm infants (mean birthweight 1.1 kg (range 0.8-1.3 kg) gestational age 28.6 weeks (range 26-30 w] from 30 to 35 weeks of post-menstrual (PM) age. Recognizable rhythmical sucking bursts were recorded at 28 w...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90100-8
更新日期：1985-07-01 00:00:00
abstract：BACKGROUND:Retinopathy of prematurity (ROP) is often associated with visual impairment and multiple developmental disabilities. AIMS:As most of the previous studies include infants with brain lesions, that can determine visual impairment per se, a cohort of low neurological risk preterm infants without ROP and with va...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105134
更新日期：2020-09-01 00:00:00
abstract：AIM:To assess whether attrition rate influences outcome in the follow-up of very preterm infants. STUDY DESIGN:In a national follow-up study of infants born alive in 1983 in the Netherlands with a gestational age less than 32 weeks and/or a birth weight less than 1500 g, outcome was assessed separately for adolescents...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2005.07.006
更新日期：2005-11-01 00:00:00
abstract：:Increasing public awareness of the prone sleeping position, maternal smoking and overheating as potentially avoidable risk factors for the sudden infant death syndrome (SIDS) has been accompanied by a dramatic reduction in mortality. The results of two population based studies of SIDS in Avon are compared; the first o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90208-9
更新日期：1994-09-15 00:00:00
abstract：:Pulse oximetry screening is a highly specific, moderately sensitive test for detecting critical congenital heart defects (CCHDs) that meets the criteria for universal screening. The possibility of using pulse oximetry as a screening test was first investigated over 10 years ago and since then data from more than 370,0...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)50006-0
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Maternal pre-pregnancy obesity, in term-born children, is associated with an increased risk of attention problems, however this relationship has not been explored among children born extremely preterm. AIM:To estimate the risk of attention problems at age 10years in children born very preterm to overweight ...
journal_title：Early human development
pub_type： 杂志文章,多中心研究
doi：10.1016/j.earlhumdev.2017.08.002
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND AND AIMS:Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and r...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.01.006
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Few studies describe in detail the pregnancy and early development of infants with Prader-Willi syndrome (PWS). However, variations at these early stages may partially account for differences in the later phenotype. A recent paper described an abnormally high number of problems in pregnancy and early infancy...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.08.007
更新日期：2008-05-01 00:00:00
abstract：BACKGROUND:Toll-like receptors (TLRs) are part of the highly conserved components of the innate immune system, and have been investigated extensively; however, little is known about TLR function during early postnatal life, a critical period for immune maturation. AIMS:In order to achieve a more complete understanding...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.03.013
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:The sudden infant death syndrome (SIDS) is still the main cause of postneonatal infant death and its cause is still unknown. Recently, the medullary serotonergic network deficiency theory has been proposed and an association between SIDS and neuronal plasticity has also been suggested. The growth-associated ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.08.017
更新日期：2003-12-01 00:00:00
abstract：INTRODUCTION:The 2D:4D digit ratio is sexually-dimorphic, probably due to testosterone action through the perinatal period. We characterize the 2D:4D ratio in newborn (NB) infants, in between the pre- and postnatal surges of testosterone, and relate it to the mother's 2D:4D and to testosterone levels in the amniotic fl...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.08.009
更新日期：2013-02-01 00:00:00
abstract：:In this study the seven postural responses selected by Vojta to evaluate neuromotor development were applied to 68 very low birth weight (VLBW) (greater than 1500 g) infants and to 28 healthy infants of normal birth weight (less than 2500 g). Of the 68 VLBW infants, 41 were small for gestational age and 27 appropriate...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90140-e
更新日期：1990-11-01 00:00:00
