Abstract：
BACKGROUND:Preterm newborns have low vitamin A reserves at birth, which increases their risk of morbidity and mortality. In the absence of supplementation, breast milk is the only source of this nutrient for exclusively breastfed infants. AIMS:To assess retinol concentration in preterm milk and the relationship between this retinol concentration and lactation phase, degree of prematurity, and maternal serum retinol level. STUDY DESIGN:Longitudinal study. SUBJECTS:Fifty-eight preterm mothers. OUTCOME MEASURES:Colostrum (1-3d), transitional (7-15d), and mature human milk (30-55d) samples were collected. Maternal blood was collected once at postpartum. Retinol level was measured using high-performance liquid chromatography. RESULTS:Milk retinol concentration was statistically different between lactation phases (p<0.001): 2.84±1.05μmol/L in colostrum (58), 3.47±1.28μmol/L in transitional (58), and 2.03±0.61μmol/L in mature milk (30). No difference was found in milk retinol levels between groups with different degrees of prematurity (p>0.05). Maternal serum retinol (1.82±0.50μmol/L) did not correlate with milk levels (p>0.05). CONCLUSIONS:Retinol level in preterm milk seems to be independent of the degree of prematurity and maternal serum status. A significant increase in micronutrient levels in transitional milk was observed, which is likely to contribute to reserves in the premature liver.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Lima MS,da Silva Ribeiro KD,Pires JF,Bezerra DF,Bellot PE,de Oliveira Weigert LP,Dimenstein Rdoi
10.1016/j.earlhumdev.2017.01.006subject
Has Abstractpub_date
2017-01-01 00:00:00pages
41-45eissn
0378-3782issn
1872-6232pii
S0378-3782(16)30347-4journal_volume
106-107pub_type
杂志文章abstract：:Prior research in newborns has shown that head-up and head-down tilting elicits sustained increases and decreases in heart rate, respectively. Other studies in older infants have suggested that the pattern of heart rate responses to head-up tilting varies with risk for sudden infant death syndrome (SIDS). In this stud...
journal_title：Early human development
pub_type： 杂志文章
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journal_title：Early human development
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journal_title：Early human development
pub_type： 杂志文章
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journal_title：Early human development
pub_type： 杂志文章,多中心研究
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journal_title：Early human development
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journal_title：Early human development
pub_type： 临床试验,杂志文章
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journal_title：Early human development
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journal_title：Early human development
pub_type： 杂志文章,评审
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journal_title：Early human development
pub_type： 杂志文章
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(96)01749-5
更新日期：1996-09-20 00:00:00
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journal_title：Early human development
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2020-12-01 00:00:00
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journal_title：Early human development
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journal_title：Early human development
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journal_title：Early human development
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Early human development
pub_type： 杂志文章
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pub_type： 杂志文章,实务指引,评审
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更新日期：2008-08-01 00:00:00
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pub_type： 杂志文章
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journal_title：Early human development
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journal_title：Early human development
pub_type： 杂志文章,评审
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journal_title：Early human development
pub_type： 杂志文章
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journal_title：Early human development
pub_type： 杂志文章
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