Abstract:
BACKGROUND:Antenatal depression is associated with adverse social-emotional and behavioural outcomes during childhood but there has been little investigation of the impact on infant neurodevelopment during the first postnatal year. AIMS:The aim of this study was to assess the impact of depression during pregnancy on infant cognitive, language and motor development at six and twelve months using a prospective longitudinal study design. PARTICIPANTS:Pregnant women with a clinical diagnosis of Major Depressive Disorder (MDD; n = 23), a history of MDD (n = 34) and a control group (n = 43) and their infants. OUTCOME MEASURES:MDD was measured during pregnancy and both maternal depression and infant cognitive, language and motor development were measured at six and twelve months postpartum. RESULTS:At six months, infants in the MDD group had lower motor development scores (M = 95.48, SD = 11.87) compared with controls (M = 99.97, SD = 10.64, p = .026) after controlling for maternal concurrent depression scores. At twelve months, infants in the MDD group had lower language scores (M = 87.33, SD = 10.54) compared with controls (M = 95.06, SD = 11.78, p = .037) which attenuated after controlling for maternal concurrent depression. CONCLUSIONS:These data contribute to the growing literature investigating the impact of antenatal depression on infant cognitive, language and motor development within the first postnatal year. The association between maternal depression and lower infant motor scores highlights the importance of early intervention for both mothers and infants in situations where maternal well-being is at risk.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
O'Leary N,Jairaj C,Molloy EJ,McAuliffe FM,Nixon E,O'Keane Vdoi
10.1016/j.earlhumdev.2019.05.021subject
Has Abstractpub_date
2019-07-01 00:00:00pages
41-46eissn
0378-3782issn
1872-6232pii
S0378-3782(19)30028-3journal_volume
134pub_type
杂志文章abstract::Interfacility transport is a necessary part of hospital care. Neonates often need to access specialist input at different sites necessitating a reliable transfer process. Services have evolved significantly over the last ten years to meet this need. This followed the recognition that ad hoc arrangements were unreliabl...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2013.09.004
更新日期:2013-11-01 00:00:00
abstract::Retinol-binding protein (RBP) and prealbumin (PA) are potentially useful indicators of inadequate protein and/or energy intake. Concentrations of RBP and PA were determined in cord blood of 117 infants and were found to be lower before 37 weeks gestation than at term. Adult subjects had substantially higher concentrat...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(83)90068-3
更新日期:1983-07-01 00:00:00
abstract:BACKGROUND:The sudden infant death syndrome (SIDS) is still the main cause of postneonatal infant death and its cause is still unknown. Recently, the medullary serotonergic network deficiency theory has been proposed and an association between SIDS and neuronal plasticity has also been suggested. The growth-associated ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2003.08.017
更新日期:2003-12-01 00:00:00
abstract::The calculation of descriptive statistics includes the calculation of standard error and confidence interval, an inevitable component of data analysis in inferential statistics. This paper provides pointers as to how to do this in Microsoft Excel™. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.01.013
更新日期:2018-03-01 00:00:00
abstract::We assessed the relation of perinatal factors to severe hypothyroxinemia of prematurity, defined as thyroxine value more than 2.6 standard deviations below the mean for newborns. The 365 survivors of birth before 32 weeks gestation were enrolled in a population-based study of the correlates of neonatal brain injury. I...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(96)01843-9
更新日期:1997-01-20 00:00:00
abstract:BACKGROUND:Extremely-low-birth-weight (ELBW) children without severe brain injury or CP are at high risk of developing deficits within cognition, attention, behavior and motor function. Assessing the quality of an infant's spontaneous motor-repertoire included in Prechtl's General-Movement-Assessment (GMA) has been sho...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.07.005
更新日期:2014-10-01 00:00:00
abstract::The IPAT Anxiety Scale was administered to a large sample of primiparous women from an economically disadvantaged population in their third trimester of pregnancy. At birth and at three and six months postpartum, the infants and mothers were assessed using a variety of behavioral and standardized procedures. Results i...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(81)90034-7
更新日期:1981-07-01 00:00:00
abstract::It is becoming increasingly apparent that pyridoxine responsive homocystinuria patients are being missed by newborn screening programs. The possibility that screening for homocystine, rather than the methionine, might be more effective was investigated by comparing homocystine and methionine levels of non-responsive p...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(96)01860-9
更新日期:1997-04-25 00:00:00
abstract:OBJECTIVE:We evaluated the effect of maternal administration of betamethasone (0.2 mg/kg per day) on mitogen-induced lymphocyte proliferation and interleukin-2 (IL-2) production by maternal, fetal, and neonatal rat splenic lymphocytes. STUDY DESIGN:Betamethasone was injected intramuscularly on days 19 and 20 of gestat...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90028-0
更新日期:1994-01-01 00:00:00
abstract::221 small-for-dates (SFD) and 244 average-for-dates (AFD) children were personally examined at birth, and seen thereafter at regular intervals up to 4 years, when a thorough assessment was made. There was an excess of SFD children with major congenital abnormalities; but no difference between the groups in the number ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(83)90007-5
更新日期:1983-10-01 00:00:00
abstract:BACKGROUND:The second-to-fourth digit ratio (2D:4D) reflects prenatal estrogen and testosterone exposure, and is established in utero. Sex steroids are implicated in development and progression of primary brain tumors. AIMS:To investigate whether there is a link between 2D:4D ratio and primary brain tumors, and age at...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.10.003
更新日期:2016-12-01 00:00:00
abstract::Soluble fibrinogen--fibrin complex levels were found to be significantly higher in plasma samples from pregnant women with babies suffering from intrauterine growth retardation, when compared with levels found in normal pregnancy. As soluble fibrinogen--fibrin complexes are formed following activation of the coagulati...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(78)90006-3
更新日期:1978-07-01 00:00:00
abstract::Low birthweight has been associated with diseases and disorders later in life. It has been suggested that this is caused by the impaired development of abdominal organs, especially in cases of growth retardation. Besides general malnutrition of the fetus, preferential bloodflow to the heart and brain may further depri...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00073-x
更新日期:1998-04-17 00:00:00
abstract::Whether preeclampsia affects the fetal hematologic system still remains a controversial issue. The purpose of this series was to examine the hypothesis that preeclampsia may or may not cause adverse effects on fetal hemogram, including erythrocytes, leukocytes, and platelets. In addition, no one, to date, has reported...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90150-3
更新日期:1994-05-01 00:00:00
abstract::This study documents the longitudinal development of head control in 104 infants born at 25-33 weeks gestation. Protective side turning of the head was found to have a developmental sequence of reducing spinal extension. In the 93 infants with normal motor outcome, individual differences in the rate of development cor...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90074-x
更新日期:1985-09-01 00:00:00
abstract::Given the widely acknowledged inverse relationship between birth weight and blood pressure, a raised blood pressure in the offspring of smoking mothers as compared to those whose mothers did not smoke, would be anticipated by virtue of the reduction in birth weight associated with smoking during pregnancy. The objecti...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(99)00064-x
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Few studies describe in detail the pregnancy and early development of infants with Prader-Willi syndrome (PWS). However, variations at these early stages may partially account for differences in the later phenotype. A recent paper described an abnormally high number of problems in pregnancy and early infancy...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2007.08.007
更新日期:2008-05-01 00:00:00
abstract::gamma-Aminobutyric acid (GABA) concentrations in cerebrospinal fluid (CSF) were measured in 20 neonates with various gestational and postnatal ages. These concentrations varied between 9 and 45 nmol/ml which is approximately 20-100 times the concentrations found in adults. CSF GABA concentrations tended to decrease wi...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(82)90007-x
更新日期:1982-10-01 00:00:00
abstract::Vascular tumours (haemangiomas and malformations) are common tumours of infancy and childhood. They represent a group of mostly benign conditions, which present early, can grow rapidly and be symptomatic or disfiguring. There are various management options, with different cosmetic and functional outcomes. Haemangiomas...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.08.017
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Even though the biological norm in humans is frequent on demand breastfeeding, sparse feeding intervals have become the cultural norm in most Western countries due to a history of on schedule breastfeeding. This discrepancy between the biological basis and the culturally driven practice continues to interfer...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105242
更新日期:2020-12-01 00:00:00
abstract::Advances in pharmacology and technology have sharply reduced mortality of extremely preterm infants at the expense of an increasing number of survivors with handicaps and disabilities. The EURONIC study among neonatal intensive care units across Europe demonstrates that treatment of infants born at the limits of viabi...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.10.004
更新日期:2005-12-01 00:00:00
abstract::In the infant, sucking behaviour is one of the first coordinated muscular activities. It is under the control of the brainstem. In utero sucking is observed from 13 weeks' gestation. The healthy full-term newborn infant has a very stable rhythm of alternating bursts of sucking with pauses in between. The non-nutritive...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(00)00091-8
更新日期:2000-11-01 00:00:00
abstract::Studies in encephalopathic infants have demonstrated a brief phase of normal cerebral energetics following hypoxia-ischaemia prior to development of delayed energy failure. In experimental models, mild hypothermia has shown a consistent neuroprotective action, although its efficacy is critically dependent on the sever...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2004.10.014
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:The 2D:4D digit ratio is sexually-dimorphic, probably due to testosterone action through the perinatal period. We characterize the 2D:4D ratio in newborn (NB) infants, in between the pre- and postnatal surges of testosterone, and relate it to the mother's 2D:4D and to testosterone levels in the amniotic fl...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.08.009
更新日期:2013-02-01 00:00:00
abstract::The idea of an artificial neural network is introduced in a historical context, and the essential aspect of it, viz., the modifiable synapse, is compared to the aspect of plasticity in the natural nervous system. Based on such an artificial neural network, a model is presented for the way in which (the path along whic...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/0378-3782(93)90045-v
更新日期:1993-09-01 00:00:00
abstract::Children born preterm are at risk for later developmental disorders. The present study examined the predictive effects of neonatal, sociodemographic, and temperament characteristics on behavioral outcomes at toddlerhood, in children born preterm. The sample included 100 toddlers born preterm and with very-low-birth-we...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.09.015
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To 1) define predictors of parent presence, any holding, holding in arms, and skin-to-skin care in the NICU and 2) investigate the relationships between parent participation and a) early neurobehavior and b) developmental outcomes at age 4 to 5years among preterm infants. METHODS:Eighty-one preterm infants b...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2017.12.008
更新日期:2018-02-01 00:00:00
abstract::A new protocol for Structured Observation of Motor Performance in Infants, SOMP-I, designed to describe both progress and quality of motor performance, was evaluated concerning its ability to describe and to discriminate between the motor performance observed in different groups of infants. Sixty-eight infants born at...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(95)01678-3
更新日期:1995-11-24 00:00:00
abstract:BACKGROUND:Obstetrical and neonatal complications and/or an adverse parenting environment are risk factors for language impairment, but little is known about their effects on early word production (late talking). AIMS:To determine obstetrical and neonatal risk factors in children with delayed word production; to asses...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2006.05.009
更新日期:2007-02-01 00:00:00
abstract::Case-control studies are frequently performed in prenatal and perinatal epidemiology. For data collection, these studies often rely on self-administered questionnaires or personal interviews. Although of importance, validation of these measurement instruments received little attention in epidemiologic research so far....
journal_title:Early human development
pub_type: 评论,信件
doi:10.1016/j.earlhumdev.2010.09.372
更新日期:2011-01-01 00:00:00