HIV, Depression, and Cognitive Impairment in the Era of Effective Antiretroviral Therapy.

abstract：:Female sex workers (FSWs) continue to represent a high-risk population in need of targeted HIV prevention interventions. Targeting environmental risk factors should result in more sustainable behavior change than individual-level interventions alone. There are many types of FSWs who operate in and through a variety of...

journal_title：Current HIV/AIDS reports

authors： Pitpitan EV,Kalichman SC,Eaton LA,Strathdee SA,Patterson TL

更新日期：2013-03-01 00:00:00

abstract：:Therapeutic drug monitoring (TDM) is the process by which a patient's dosing regimen is guided by repeated measures of plasma drug concentrations. An enormous challenge with regard to TDM of antiretroviral drugs (ARV) is that the concentration goals can be moving targets. Well-designed prospective studies demonstratin...

journal_title：Current HIV/AIDS reports

authors： Kiser JJ,Anderson PL,Gerber JG

更新日期：2005-06-01 00:00:00

abstract：:Bacterial infection is a major cause of morbidity and mortality among patients with HIV living in Africa. Broadening the scope of cotrimoxazole (CTX) prophylaxis to cover patients whose CD4 counts are above 200 cells/mm(3) has been suggested as a means of improving the control of infectious disease on the continent. C...

journal_title：Current HIV/AIDS reports

authors： Spencer DC

更新日期：2007-08-01 00:00:00

abstract：:Due to the rapid expansion of first-line antiretroviral therapy in resource-limited settings (RLS), increasing numbers of people are living with HIV for prolonged periods of time. Treatment programs must now decide how to balance monitoring costs necessary to maximize health benefits for those already on treatment wit...

journal_title：Current HIV/AIDS reports

authors： Hosseinipour MC,Schechter M

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This narrative review summarizes recent data on factors associated with insulin resistance (IR) in adults with HIV, including contemporary antiretroviral therapy (ART). RECENT FINDINGS:IR remains common in persons with HIV, even those receiving contemporary ART. Generalized and abdominal obesity and ...

journal_title：Current HIV/AIDS reports

authors： Hulgan T

更新日期：2018-06-01 00:00:00

abstract：:Due to the co-occurrence of sexual risk behaviors and substance use among HIV-positive individuals, there is often a need for HIV prevention efforts to target multiple behaviors. Motivational Interviewing (MI), a widely disseminated behavior change intervention, has demonstrated effectiveness in promoting behavior cha...

journal_title：Current HIV/AIDS reports

authors： Naar-King S,Parsons JT,Johnson AM

更新日期：2012-12-01 00:00:00

abstract：:Generation of memory T cells, which mediate immunity against microbes and cancers, relies, for optimal activity, on the interactions of multiple cell types that are highly regulated through the expression of soluble factors and negative and positive receptors. Their disruption will lead to aberrant immune responses, w...

journal_title：Current HIV/AIDS reports

authors： El-Far M,Halwani R,Said E,Trautmann L,Doroudchi M,Janbazian L,Fonseca S,van Grevenynghe J,Yassine-Diab B,Sékaly RP,Haddad EK

更新日期：2008-02-01 00:00:00

abstract：:Neurocognitive compromise, a common sequela of HIV infection, ranges in severity from minor motor and information-processing speed decrements to severely incapacitating symptoms that affect functional independence. However, with the emergence of highly active antiretroviral therapy (HAART), neurocognitive phenotypes h...

journal_title：Current HIV/AIDS reports

authors： Foley J,Ettenhofer M,Wright M,Hinkin CH

更新日期：2008-11-01 00:00:00

abstract：:Neurocognitive impairment is common in people living with HIV and AIDS. Prior to highly active antiretroviral therapy (HAART), cognitive impairment primarily affected patients with advanced disease, and was a more rapidly progressive illness. With the use of HAART, cognitive impairment improved, along with the overall...

journal_title：Current HIV/AIDS reports

authors： Robinson-Papp J,Elliott KJ,Simpson DM

更新日期：2009-08-01 00:00:00

abstract：:The global HIV pandemic began to expand rapidly in southern Africa a decade later than was noted in central Africa, Europe, the Caribbean, and North America. Multiple factors played a role in this rapid expansion which led Southern Africa to become the most heavily afflicted region for HIV/AIDS globally. In this issue...

journal_title：Current HIV/AIDS reports

authors： Vermund SH,Sheldon EK,Sidat M

更新日期：2015-06-01 00:00:00

abstract：:Roughly 10 % of HIV-positive individuals worldwide have concomitant chronic hepatitis B virus (HBV) infection, with large differences between geographical regions and/or risk groups. Hepatitis B is a preventable infection with vaccines. However, it cannot be eradicated once acquired, resembling HIV and in contrast wit...

journal_title：Current HIV/AIDS reports

authors： Soriano V,Labarga P,de Mendoza C,Peña JM,Fernández-Montero JV,Benítez L,Esposito I,Barreiro P

更新日期：2015-09-01 00:00:00

abstract：:Recent policies, guidelines, and laws reflect promising preliminary outcomes among transplant recipients with HIV infection, and ethical analyses suggest that it is not justifiable to deny solid organ transplantation based solely on HIV-infection status. These studies consistently describe stable HIV disease following...

journal_title：Current HIV/AIDS reports

authors： Roland ME,Stock PG

更新日期：2006-09-01 00:00:00

abstract：:Injecting drug use is a common mode of transmission among persons with HIV/AIDS. Many HIV-infected patients meet diagnostic criteria for opioid dependence, a chronic and relapsing brain disorder. Most HIV providers, however, receive little training in substance use disorders. Opioid agonist therapy (OAT) has a stabili...

journal_title：Current HIV/AIDS reports

authors： Lum PJ,Tulsky JP

更新日期：2006-11-01 00:00:00

abstract：:Despite impressive decreases in mortality and morbidity, significant adverse events have surfaced as a result of combination antiretroviral therapy (ART). They include lipoatrophy, or subcutaneous fat wasting of the face, arms, buttocks, or legs, which can be associated with central fat accumulation. Although the unde...

journal_title：Current HIV/AIDS reports

authors： Tungsiripat M,McComsey G

更新日期：2008-05-01 00:00:00

abstract：:Several all-oral direct-acting antiviral (DAA) combination therapies including two fixed-dose combinations (FDCs) have been recently licensed for treatment of hepatitis C virus (HCV) genotype 1 infection. Results of pivotal trials with these new compounds are now also available in human immunodeficiency virus (HIV)/HC...

journal_title：Current HIV/AIDS reports

authors： Boesecke C,Rockstroh JK

更新日期：2015-09-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) infection occurs throughout the body and can have dramatic physical effects, such as neurocognitive impairment in the central nervous system (CNS). Furthermore, examining the virus that resides in the CNS is challenging due to its location and can only be done using samples ...

journal_title：Current HIV/AIDS reports

authors： Bednar MM,Sturdevant CB,Tompkins LA,Arrildt KT,Dukhovlinova E,Kincer LP,Swanstrom R

更新日期：2015-06-01 00:00:00

abstract：:HIV infection and antiretroviral therapy (ART) use are associated with perturbations in glucose and lipid metabolism. Increasing incidence of diabetes, cardiovascular disease, and obesity highlights the need for early identification and treatment of metabolic dysfunction. Newer ART regimens are less toxic for cellular...

journal_title：Current HIV/AIDS reports

authors： Willig AL,Overton ET

更新日期：2016-10-01 00:00:00

abstract：:HIV may cause several forms of peripheral neuropathy, the most common of which is distal symmetric polyneuropathy (DSP) characterized by pain and sensory deficits in a stocking-glove distribution. The pathophysiology of DSP remains largely unknown but is thought to be related both to the neurotoxicity of HIV-through i...

journal_title：Current HIV/AIDS reports

authors： Stavros K,Simpson DM

更新日期：2014-09-01 00:00:00

abstract：:The purpose of this meta-analytic study is to summarize the current science concerning the (a) prevalence of alcohol use, (b) prevalence of sexual risk behaviors, and (c) association between alcohol use and sexual risk behaviors among people livingwithHIV/AIDS (PLWHA). Studies were included if they sampled PLWHA, eval...

journal_title：Current HIV/AIDS reports

authors： Scott-Sheldon LA,Walstrom P,Carey KB,Johnson BT,Carey MP,MASH Research Team.

更新日期：2013-12-01 00:00:00

abstract：:This article reviews the antiretroviral therapy (ART) initiation criteria from published national guidelines for 94 countries (representing 86 % of global HIV burden) and compares them with the 2013 World Health Organization (WHO) ART guidelines. As of 31st of July 2014, 19 countries have adopted the WHO-recommended C...

journal_title：Current HIV/AIDS reports

authors： Gupta S,Williams B,Montaner J

更新日期：2014-12-01 00:00:00

abstract：:Persons who inject drugs (PWID) are at high risk for infection with and poor outcomes from HIV and hepatitis C virus (HCV). Well-established interventions for HIV/HCV prevention among PWID include syringe access, opioid agonist maintenance treatment, and supervised injection facilities, yet these interventions remain ...

journal_title：Current HIV/AIDS reports

authors： Coffin PO,Rowe C,Santos GM

更新日期：2015-03-01 00:00:00

abstract：:HIV is a devastating worldwide epidemic that has had substantial social and economic impacts throughout the globe. Due to the presence of a small pool of latently infected cells that persists during antiretroviral therapy (ART), HIV is not curable. Because of the high cost of ART and the lack of reliable accessibility...

journal_title：Current HIV/AIDS reports

authors： Barton KM,Palmer SE

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:End-stage organ disease prevalence is increasing among HIV-infected (HIV+) individuals. Trial and registry data confirm that solid organ transplantation (SOT) is efficacious in this population. Optimizing access to transplant and decreasing complications represent active frontiers. RECENT FINDINGS:HI...

journal_title：Current HIV/AIDS reports

authors： Werbel WA,Durand CM

更新日期：2019-06-01 00:00:00

abstract：:Pharmacy refill adherence has become an increasingly important measure of adherence to antiretroviral medications. It offers a simple, inexpensive, and valid method for measuring adherence. Over the past year, there have been several published developments in the use of pharmacy refill data to measure adherence. Given...

journal_title：Current HIV/AIDS reports

authors： Grossberg R,Gross R

更新日期：2007-12-01 00:00:00

abstract：:The population of patients with HIV infection achieving viral suppression on combination antiretroviral therapy is growing, aging, and experiencing a widening spectrum of non-AIDS diseases. Concurrently, AIDS-defining conditions are becoming less common and are variably associated with outcome. Nonetheless, the spectr...

journal_title：Current HIV/AIDS reports

authors： Justice AC

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Glycoimmunology is an emerging field focused on understanding how immune responses are mediated by glycans (carbohydrates) and their interaction with glycan-binding proteins called lectins. How glycans influence immunological functions is increasingly well understood. In a parallel way, in the HIV fie...

journal_title：Current HIV/AIDS reports

authors： Colomb F,Giron LB,Trbojevic-Akmacic I,Lauc G,Abdel-Mohsen M

更新日期：2019-04-01 00:00:00

abstract：:HIV-infected individuals are at increased risk for most types of cancer, including those typically classified as non-AIDS-defining cancers (NADCs). This increased risk is likely multifactorial, but a prominent risk factor for the increased rate of some cancers is co-infection with oncogenic viruses. Anal cancer, hepat...

journal_title：Current HIV/AIDS reports

authors： Riedel DJ,Tang LS,Rositch AF

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The discovery of innate lymphoid cells (ILCs) over the past decade has reformed principles that were once thought to be exclusive to adaptive immunity. Here, we describe ILC nomenclature and function, and provide a survey of studies examining these cells in the context of HIV/SIV infections. Particula...

journal_title：Current HIV/AIDS reports

authors： Mudd JC,Brenchley JM

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Neurological conditions associated with HIV/AIDS including central nervous system (CNS), opportunistic infections (OI), chronic conditions including HIV-associated neurocognitive disorder, and cerebrospinal fluid (CSF) viral escape remain major contributors to morbidity and mortality worldwide. CNS in...

journal_title：Current HIV/AIDS reports

authors： Thakur KT

更新日期：2020-10-01 00:00:00

abstract：:While combination antiretroviral therapy allows HIV-infected patients to have life expectancies similar to that of the general population, it may also contribute to the development of co-morbidities, such as cardiovascular disease and osteoporosis. Such complications could compromise long-term quality of life, especia...

journal_title：Current HIV/AIDS reports

authors： Eckard AR,Fowler SL,Haston JC,Dixon TC

更新日期：2016-08-01 00:00:00