Novel interventions to prevent HIV and HCV among persons who inject drugs.

Abstract:

:Persons who inject drugs (PWID) are at high risk for infection with and poor outcomes from HIV and hepatitis C virus (HCV). Well-established interventions for HIV/HCV prevention among PWID include syringe access, opioid agonist maintenance treatment, and supervised injection facilities, yet these interventions remain unavailable or inadequately resourced in much of the world. We review recent literature on biomedical and behavioral interventions to reduce the burden of HIV/HCV among PWID, with an emphasis on randomized controlled trials and quasi-experimental studies. Since 2013, there have been significant advancements in utilizing antiviral therapy and behavioral interventions for prevention among PWID, including approaches that address the unique needs of couples and sex workers. In addition, there have been significant developments in pharmacotherapies for substance use and the implementation of naloxone for opioid overdose prevention. Notwithstanding multiple ongoing structural challenges in delivering HIV/HCV prevention interventions to PWID, these emerging and rigorously evaluated interventions expand possibilities for prevention among PWID.

journal_name

Curr HIV/AIDS Rep

journal_title

Current HIV/AIDS reports

authors

Coffin PO,Rowe C,Santos GM

doi

10.1007/s11904-014-0248-2

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

145-63

issue

1

eissn

1548-3568

issn

1548-3576

journal_volume

12

pub_type

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