HIV-related neurocognitive impairment in the HAART era.

abstract：:Nine months of daily isoniazid is efficacious in treating latent M. tuberculosis infection, but completion rates are low, limiting treatment effectiveness. In 2011, three important studies were published involving novel regimens for the treatment of latent M. tuberculosis infection. At least 36 months of isoniazid was...

journal_title：Current HIV/AIDS reports

authors： Person AK,Sterling TR

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to describe the epidemiology of HIV among female sex workers (FSWs) in China over the past decade, to summarize current gaps in knowledge regarding risk factors, and to identify new directions for HIV prevention strategies. RECENT FINDINGS:We summarized national and regional levels o...

journal_title：Current HIV/AIDS reports

authors： Zhang H,Hsieh E,Wang L,Liao S

更新日期：2020-04-01 00:00:00

abstract：:Adolescents are critical to efforts to end the AIDS epidemic. Few national AIDS strategies explicitly program for children in their second decade of life. Adolescents (aged 10-19 years) are therefore largely invisible in global, regional, and country HIV and AIDS reports making it difficult to assess progress in this ...

journal_title：Current HIV/AIDS reports

authors： Kasedde S,Luo C,McClure C,Chandan U

更新日期：2013-06-01 00:00:00

abstract：:HIV infection and antiretroviral therapy (ART) use are associated with perturbations in glucose and lipid metabolism. Increasing incidence of diabetes, cardiovascular disease, and obesity highlights the need for early identification and treatment of metabolic dysfunction. Newer ART regimens are less toxic for cellular...

journal_title：Current HIV/AIDS reports

authors： Willig AL,Overton ET

更新日期：2016-10-01 00:00:00

abstract：:Generation of memory T cells, which mediate immunity against microbes and cancers, relies, for optimal activity, on the interactions of multiple cell types that are highly regulated through the expression of soluble factors and negative and positive receptors. Their disruption will lead to aberrant immune responses, w...

journal_title：Current HIV/AIDS reports

authors： El-Far M,Halwani R,Said E,Trautmann L,Doroudchi M,Janbazian L,Fonseca S,van Grevenynghe J,Yassine-Diab B,Sékaly RP,Haddad EK

更新日期：2008-02-01 00:00:00

abstract：:The course of HIV research has led to a multitude of interventions to prevent and treat HIV. With the arrival of more effective interventions comes the need to end, or de-implement, less effective interventions. PURPOSE OF REVIEW: To describe the state of de-implementation research in HIV and provide a rationale for e...

journal_title：Current HIV/AIDS reports

authors： McKay VR,Tetteh EK,Reid MJ,Ingaiza LM

更新日期：2020-10-01 00:00:00

abstract：:This article reviews the magnitude and spectrum of ocular complications of HIV infection in sub-Sahara Africa. A literature search was done using PubMed, Google, and UpToDate and by talking to ophthalmologists and HIV experts working in the region. Ocular complications of HIV infection, mostly retinal, are seen in 29%...

journal_title：Current HIV/AIDS reports

authors： Nkomazana O,Tshitswana D

更新日期：2008-08-01 00:00:00

abstract：:HIV-infected individuals are at increased risk for most types of cancer, including those typically classified as non-AIDS-defining cancers (NADCs). This increased risk is likely multifactorial, but a prominent risk factor for the increased rate of some cancers is co-infection with oncogenic viruses. Anal cancer, hepat...

journal_title：Current HIV/AIDS reports

authors： Riedel DJ,Tang LS,Rositch AF

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to provide a thorough overview of methods used for recruitment, network data collection, and network data management in a network-based study of rural people who use drugs (PWUD) and to offer methodological recommendations for future research on rural drug use. RECENT FIN...

journal_title：Current HIV/AIDS reports

authors： Young AM,Rudolph AE,Havens JR

更新日期：2018-04-01 00:00:00

abstract：:Pharmacy refill adherence has become an increasingly important measure of adherence to antiretroviral medications. It offers a simple, inexpensive, and valid method for measuring adherence. Over the past year, there have been several published developments in the use of pharmacy refill data to measure adherence. Given...

journal_title：Current HIV/AIDS reports

authors： Grossberg R,Gross R

更新日期：2007-12-01 00:00:00

abstract：:The HIV pandemic has disproportionately impacted sub-Saharan Africa and Southern Africa in particular. The concurrent presence of overlapping epidemic drivers likely underpins how and why the HIV epidemic is so explosive in this region, with implications for understanding approaches to reduce transmission. In this rev...

journal_title：Current HIV/AIDS reports

authors： McKinnon LR,Karim QA

更新日期：2016-06-01 00:00:00

abstract：:The role of voluntary counseling and testing (VCT)of HIV in resource-limited settings has recently broadened from primarily that of a prevention intervention to its identification as the key entry point into expanding access to life-saving antiretroviral therapy, additional HIV-specific medical care, and other support...

journal_title：Current HIV/AIDS reports

authors： Liechty CA

更新日期：2004-12-01 00:00:00

abstract：:Due to life-enhancing effects of antiretroviral therapy, HIV-positive persons have the potential for long life comparable to their uninfected peers. Older women (age 50+) living with HIV (OWLH) are often an under-recognized aging group. We conducted a systematic review to examine psychosocial factors that impact how O...

journal_title：Current HIV/AIDS reports

authors： Rubtsova AA,Kempf MC,Taylor TN,Konkle-Parker D,Wingood GM,Holstad MM

更新日期：2017-02-01 00:00:00

abstract：:HIV may cause several forms of peripheral neuropathy, the most common of which is distal symmetric polyneuropathy (DSP) characterized by pain and sensory deficits in a stocking-glove distribution. The pathophysiology of DSP remains largely unknown but is thought to be related both to the neurotoxicity of HIV-through i...

journal_title：Current HIV/AIDS reports

authors： Stavros K,Simpson DM

更新日期：2014-09-01 00:00:00

abstract：:Substance users are at elevated risk for HIV. HIV researchers, particularly at the intersection of HIV and substance use, have requested new methods to better understand and address this important area. New technologies, such as social media and mobile applications, are increasingly being used as research tools in stu...

journal_title：Current HIV/AIDS reports

authors： Young SD,Swendeman D,Holloway IW,Reback CJ,Kao U

更新日期：2015-12-01 00:00:00

abstract：:Combined antiretroviral therapy (CART) has turned HIV-infection to a treatable chronic disease during which many patients survive to middle and older age. However, they prematurely develop non-AIDS comorbidities such as cardiovascular disease, metabolic syndrome, diabetes, and HIV-associated neurocognitive disorders (...

journal_title：Current HIV/AIDS reports

authors： Monsuez JJ,Belin C,Bouchaud O

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In the absence of antiretroviral therapy (ART), more than 50% of perinatally HIV-infected children die by 2 years of age. Early ART from infancy is therefore a global recommendation and significantly improves immune health, child survival, and disease outcome. However, even early treatment does not pr...

journal_title：Current HIV/AIDS reports

authors： Berendam SJ,Nelson AN,Goswami R,Persaud D,Haigwood NL,Chahroudi A,Fouda GG,Permar SR

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Early diagnosis and treatment of HIV following seroconversion improves individual and population health. Using published data on pre-treatment CD4 cell counts, we benchmarked the level of immunodeficiency at HIV diagnosis and ART initiation in the "real world" against those of the treatment and co...

journal_title：Current HIV/AIDS reports

authors： Nash D,Robertson M

更新日期：2019-08-01 00:00:00

abstract：:Sustained retention represents an enduring and evolving challenge to HIV treatment programs in Africa. We present a theoretical framework for sustained retention borrowing from ecologic principles of sustainability and dynamic adaptation. We posit that sustained retention from the patient perspective is dependent on t...

journal_title：Current HIV/AIDS reports

authors： Roy M,Czaicki N,Holmes C,Chavan S,Tsitsi A,Odeny T,Sikazwe I,Padian N,Geng E

更新日期：2016-06-01 00:00:00

abstract：:The population of patients with HIV infection achieving viral suppression on combination antiretroviral therapy is growing, aging, and experiencing a widening spectrum of non-AIDS diseases. Concurrently, AIDS-defining conditions are becoming less common and are variably associated with outcome. Nonetheless, the spectr...

journal_title：Current HIV/AIDS reports

authors： Justice AC

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent literature defining tissue-resident memory T cells (TRM) and discusses implications for HIV pathogenesis, vaccines, and eradication efforts. RECENT FINDINGS:Investigations using animal models and human tissues have identified a TRM transcriptional profile and elucidated ...

journal_title：Current HIV/AIDS reports

authors： Shacklett BL,Ferre AL,Kiniry BE

更新日期：2020-04-01 00:00:00

abstract：:Injecting drug use is a common mode of transmission among persons with HIV/AIDS. Many HIV-infected patients meet diagnostic criteria for opioid dependence, a chronic and relapsing brain disorder. Most HIV providers, however, receive little training in substance use disorders. Opioid agonist therapy (OAT) has a stabili...

journal_title：Current HIV/AIDS reports

authors： Lum PJ,Tulsky JP

更新日期：2006-11-01 00:00:00

abstract：:Roughly 10 % of HIV-positive individuals worldwide have concomitant chronic hepatitis B virus (HBV) infection, with large differences between geographical regions and/or risk groups. Hepatitis B is a preventable infection with vaccines. However, it cannot be eradicated once acquired, resembling HIV and in contrast wit...

journal_title：Current HIV/AIDS reports

authors： Soriano V,Labarga P,de Mendoza C,Peña JM,Fernández-Montero JV,Benítez L,Esposito I,Barreiro P

更新日期：2015-09-01 00:00:00

abstract：:Access to potent antiretroviral medications greatly reduces morbidity and mortality due to HIV/AIDS, but drug toxicity limits treatment success in many individuals. The field of pharmacogenomics strives to understand the influence of human genetic variants in response to medications. Investigators have begun to identi...

journal_title：Current HIV/AIDS reports

authors： Haas DW

更新日期：2006-07-01 00:00:00

abstract：:HIV infection is one of the strongest risk factors for anal squamous cell cancer (ASCC). Most ASCC are caused by HPV, and most HPV-associated ASCC are caused by HPV-16. Anal HPV infections are very common in men who have sex with men (MSM), and nearly universal among HIV-infected MSM. High-grade anal intraepithelial n...

journal_title：Current HIV/AIDS reports

authors： Schim van der Loeff MF,Mooij SH,Richel O,de Vries HJ,Prins JM

更新日期：2014-09-01 00:00:00

abstract：:An emerging body of evidence suggests that intergenerational sexual partnerships may increase risk of HIV acquisition among young men who have sex with men (YMSM). However, no studies have comprehensively evaluated literature in this area. We applied a scoping review methodology to explore the relationships between ag...

journal_title：Current HIV/AIDS reports

authors： Anema A,Marshall BD,Stevenson B,Gurm J,Montaner G,Small W,Roth EA,Lima VD,Montaner JS,Moore D,Hogg RS

更新日期：2013-12-01 00:00:00

abstract：:For the last three decades, sub-Saharan Africa has been the epicentre of the HIV epidemic. Some key drivers of the epidemic are specific to this region and there is an urgent need to develop context-specific strategies to reduce HIV-related burden. Implementation frameworks should endeavour to combine structural, beha...

journal_title：Current HIV/AIDS reports

authors： Shanaube K,Bock P

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Neurological conditions associated with HIV/AIDS including central nervous system (CNS), opportunistic infections (OI), chronic conditions including HIV-associated neurocognitive disorder, and cerebrospinal fluid (CSF) viral escape remain major contributors to morbidity and mortality worldwide. CNS in...

journal_title：Current HIV/AIDS reports

authors： Thakur KT

更新日期：2020-10-01 00:00:00

abstract：:Therapeutic drug monitoring (TDM) is the process by which a patient's dosing regimen is guided by repeated measures of plasma drug concentrations. An enormous challenge with regard to TDM of antiretroviral drugs (ARV) is that the concentration goals can be moving targets. Well-designed prospective studies demonstratin...

journal_title：Current HIV/AIDS reports

authors： Kiser JJ,Anderson PL,Gerber JG

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Advances in short- and long-acting pre-exposure prophylaxis (PrEP) technologies have incentivized the need to understand how individuals make trade-offs and competing decisions regarding PrEP modalities. The purpose of this review was to examine how researchers have conceptualized and measured attribu...

journal_title：Current HIV/AIDS reports

authors： Bauermeister JA,Downs JS,Krakower DS

更新日期：2020-06-01 00:00:00