Breaking the Glyco-Code of HIV Persistence and Immunopathogenesis.

abstract：:Due to the rapid expansion of first-line antiretroviral therapy in resource-limited settings (RLS), increasing numbers of people are living with HIV for prolonged periods of time. Treatment programs must now decide how to balance monitoring costs necessary to maximize health benefits for those already on treatment wit...

journal_title：Current HIV/AIDS reports

authors： Hosseinipour MC,Schechter M

更新日期：2010-08-01 00:00:00

abstract：:An emerging body of evidence suggests that intergenerational sexual partnerships may increase risk of HIV acquisition among young men who have sex with men (YMSM). However, no studies have comprehensively evaluated literature in this area. We applied a scoping review methodology to explore the relationships between ag...

journal_title：Current HIV/AIDS reports

authors： Anema A,Marshall BD,Stevenson B,Gurm J,Montaner G,Small W,Roth EA,Lima VD,Montaner JS,Moore D,Hogg RS

更新日期：2013-12-01 00:00:00

abstract：:The availability of potent combination antiretroviral therapy has changed the long-term prognosis for people living with HIV/AIDS. There is increasing concern, however, about the effect of HIV therapy on lipid disorders and subsequent development of coronary artery disease. Virtually all classes of antiretroviral drug...

journal_title：Current HIV/AIDS reports

authors： Umeh OC,Currier JS

更新日期：2005-08-01 00:00:00

abstract：:T-cell activation has long been considered a central mediator of HIV pathogenesis. High T-cell activation levels predict more rapid disease progression in untreated patients and decreased treatment-mediated CD4+ T-cell gains during antiretroviral therapy, independent of plasma HIV RNA levels, and may be the primary fe...

journal_title：Current HIV/AIDS reports

authors： Hunt PW

更新日期：2007-02-01 00:00:00

abstract：:Substance users are at elevated risk for HIV. HIV researchers, particularly at the intersection of HIV and substance use, have requested new methods to better understand and address this important area. New technologies, such as social media and mobile applications, are increasingly being used as research tools in stu...

journal_title：Current HIV/AIDS reports

authors： Young SD,Swendeman D,Holloway IW,Reback CJ,Kao U

更新日期：2015-12-01 00:00:00

abstract：:Increased access to testing and treatment means HIV can be managed as a chronic illness, though successful management requires continued engagement with the health care system. Most of the global HIV burden is in sub-Saharan Africa where rates of new infections are consistently higher in women versus men. Pregnancy is...

journal_title：Current HIV/AIDS reports

authors： Psaros C,Remmert JE,Bangsberg DR,Safren SA,Smit JA

更新日期：2015-03-01 00:00:00

abstract：:Neurocognitive impairment is common in people living with HIV and AIDS. Prior to highly active antiretroviral therapy (HAART), cognitive impairment primarily affected patients with advanced disease, and was a more rapidly progressive illness. With the use of HAART, cognitive impairment improved, along with the overall...

journal_title：Current HIV/AIDS reports

authors： Robinson-Papp J,Elliott KJ,Simpson DM

更新日期：2009-08-01 00:00:00

abstract：:HIV-infected individuals are at increased risk for most types of cancer, including those typically classified as non-AIDS-defining cancers (NADCs). This increased risk is likely multifactorial, but a prominent risk factor for the increased rate of some cancers is co-infection with oncogenic viruses. Anal cancer, hepat...

journal_title：Current HIV/AIDS reports

authors： Riedel DJ,Tang LS,Rositch AF

更新日期：2015-09-01 00:00:00

abstract：:Combined antiretroviral therapy (CART) has turned HIV-infection to a treatable chronic disease during which many patients survive to middle and older age. However, they prematurely develop non-AIDS comorbidities such as cardiovascular disease, metabolic syndrome, diabetes, and HIV-associated neurocognitive disorders (...

journal_title：Current HIV/AIDS reports

authors： Monsuez JJ,Belin C,Bouchaud O

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe a small city/rural area HIV prevention project (the Cross Border Project) implemented in Ning Ming County, Guangxi Province, China, and Lang Son province, Vietnam, and consider its implications for addressing the opioid/heroin epidemic in small cities/rural areas in the USA. The descriptio...

journal_title：Current HIV/AIDS reports

authors： Des Jarlais DC,Hammett TM,Kieu B,Chen Y,Feelemyer J

更新日期：2018-08-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) infection occurs throughout the body and can have dramatic physical effects, such as neurocognitive impairment in the central nervous system (CNS). Furthermore, examining the virus that resides in the CNS is challenging due to its location and can only be done using samples ...

journal_title：Current HIV/AIDS reports

authors： Bednar MM,Sturdevant CB,Tompkins LA,Arrildt KT,Dukhovlinova E,Kincer LP,Swanstrom R

更新日期：2015-06-01 00:00:00

abstract：:Pharmacy refill adherence has become an increasingly important measure of adherence to antiretroviral medications. It offers a simple, inexpensive, and valid method for measuring adherence. Over the past year, there have been several published developments in the use of pharmacy refill data to measure adherence. Given...

journal_title：Current HIV/AIDS reports

authors： Grossberg R,Gross R

更新日期：2007-12-01 00:00:00

abstract：:This article reviews the antiretroviral therapy (ART) initiation criteria from published national guidelines for 94 countries (representing 86 % of global HIV burden) and compares them with the 2013 World Health Organization (WHO) ART guidelines. As of 31st of July 2014, 19 countries have adopted the WHO-recommended C...

journal_title：Current HIV/AIDS reports

authors： Gupta S,Williams B,Montaner J

更新日期：2014-12-01 00:00:00

abstract：:Generation of memory T cells, which mediate immunity against microbes and cancers, relies, for optimal activity, on the interactions of multiple cell types that are highly regulated through the expression of soluble factors and negative and positive receptors. Their disruption will lead to aberrant immune responses, w...

journal_title：Current HIV/AIDS reports

authors： El-Far M,Halwani R,Said E,Trautmann L,Doroudchi M,Janbazian L,Fonseca S,van Grevenynghe J,Yassine-Diab B,Sékaly RP,Haddad EK

更新日期：2008-02-01 00:00:00

abstract：:Sustained retention represents an enduring and evolving challenge to HIV treatment programs in Africa. We present a theoretical framework for sustained retention borrowing from ecologic principles of sustainability and dynamic adaptation. We posit that sustained retention from the patient perspective is dependent on t...

journal_title：Current HIV/AIDS reports

authors： Roy M,Czaicki N,Holmes C,Chavan S,Tsitsi A,Odeny T,Sikazwe I,Padian N,Geng E

更新日期：2016-06-01 00:00:00

abstract：:The population of patients with HIV infection achieving viral suppression on combination antiretroviral therapy is growing, aging, and experiencing a widening spectrum of non-AIDS diseases. Concurrently, AIDS-defining conditions are becoming less common and are variably associated with outcome. Nonetheless, the spectr...

journal_title：Current HIV/AIDS reports

authors： Justice AC

更新日期：2010-05-01 00:00:00

abstract：:Therapeutic drug monitoring (TDM) is the process by which a patient's dosing regimen is guided by repeated measures of plasma drug concentrations. An enormous challenge with regard to TDM of antiretroviral drugs (ARV) is that the concentration goals can be moving targets. Well-designed prospective studies demonstratin...

journal_title：Current HIV/AIDS reports

authors： Kiser JJ,Anderson PL,Gerber JG

更新日期：2005-06-01 00:00:00

abstract：:HIV infection and antiretroviral therapy (ART) use are associated with perturbations in glucose and lipid metabolism. Increasing incidence of diabetes, cardiovascular disease, and obesity highlights the need for early identification and treatment of metabolic dysfunction. Newer ART regimens are less toxic for cellular...

journal_title：Current HIV/AIDS reports

authors： Willig AL,Overton ET

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to describe the epidemiology of HIV among female sex workers (FSWs) in China over the past decade, to summarize current gaps in knowledge regarding risk factors, and to identify new directions for HIV prevention strategies. RECENT FINDINGS:We summarized national and regional levels o...

journal_title：Current HIV/AIDS reports

authors： Zhang H,Hsieh E,Wang L,Liao S

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Early diagnosis and treatment of HIV following seroconversion improves individual and population health. Using published data on pre-treatment CD4 cell counts, we benchmarked the level of immunodeficiency at HIV diagnosis and ART initiation in the "real world" against those of the treatment and co...

journal_title：Current HIV/AIDS reports

authors： Nash D,Robertson M

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Aligning HIV treatment services with patient preferences can promote long-term engagement. A rising number of studies solicit such preferences using discrete choice experiments, but have not been systematically reviewed to seek generalizable insights. Using a systematic search, we identified eleven ch...

journal_title：Current HIV/AIDS reports

authors： Eshun-Wilson I,Kim HY,Schwartz S,Conte M,Glidden DV,Geng EH

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Neurological conditions associated with HIV/AIDS including central nervous system (CNS), opportunistic infections (OI), chronic conditions including HIV-associated neurocognitive disorder, and cerebrospinal fluid (CSF) viral escape remain major contributors to morbidity and mortality worldwide. CNS in...

journal_title：Current HIV/AIDS reports

authors： Thakur KT

更新日期：2020-10-01 00:00:00

abstract：:Injecting drug use is a common mode of transmission among persons with HIV/AIDS. Many HIV-infected patients meet diagnostic criteria for opioid dependence, a chronic and relapsing brain disorder. Most HIV providers, however, receive little training in substance use disorders. Opioid agonist therapy (OAT) has a stabili...

journal_title：Current HIV/AIDS reports

authors： Lum PJ,Tulsky JP

更新日期：2006-11-01 00:00:00

abstract：:HIV infection is one of the strongest risk factors for anal squamous cell cancer (ASCC). Most ASCC are caused by HPV, and most HPV-associated ASCC are caused by HPV-16. Anal HPV infections are very common in men who have sex with men (MSM), and nearly universal among HIV-infected MSM. High-grade anal intraepithelial n...

journal_title：Current HIV/AIDS reports

authors： Schim van der Loeff MF,Mooij SH,Richel O,de Vries HJ,Prins JM

更新日期：2014-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an overview of HCV resistance-associated substitutions (RASs) with a focus on NS3 protease and NS5A inhibitor resistance. Treatment approaches for managing resistance are also covered including the use of newly approved therapies with improved resistance profiles. RECENT FINDINGS...

journal_title：Current HIV/AIDS reports

authors： Wyles DL

更新日期：2017-12-01 00:00:00

abstract：:With the introduction of potent combination antiretroviral therapy (cART) into clinical practice, HIV-infected patients have garnered much benefit. However, kidney disease continues to be a potential complication in this group. Whereas HIV-associated nephropathy (HIVAN) was the major renal complication prior to cART, ...

journal_title：Current HIV/AIDS reports

authors： Kumar N,Perazella MA

更新日期：2014-09-01 00:00:00

abstract：:While combination antiretroviral therapy allows HIV-infected patients to have life expectancies similar to that of the general population, it may also contribute to the development of co-morbidities, such as cardiovascular disease and osteoporosis. Such complications could compromise long-term quality of life, especia...

journal_title：Current HIV/AIDS reports

authors： Eckard AR,Fowler SL,Haston JC,Dixon TC

更新日期：2016-08-01 00:00:00

abstract：:The role of voluntary counseling and testing (VCT)of HIV in resource-limited settings has recently broadened from primarily that of a prevention intervention to its identification as the key entry point into expanding access to life-saving antiretroviral therapy, additional HIV-specific medical care, and other support...

journal_title：Current HIV/AIDS reports

authors： Liechty CA

更新日期：2004-12-01 00:00:00

abstract：:Roughly 10 % of HIV-positive individuals worldwide have concomitant chronic hepatitis B virus (HBV) infection, with large differences between geographical regions and/or risk groups. Hepatitis B is a preventable infection with vaccines. However, it cannot be eradicated once acquired, resembling HIV and in contrast wit...

journal_title：Current HIV/AIDS reports

authors： Soriano V,Labarga P,de Mendoza C,Peña JM,Fernández-Montero JV,Benítez L,Esposito I,Barreiro P

更新日期：2015-09-01 00:00:00

abstract：:The course of HIV research has led to a multitude of interventions to prevent and treat HIV. With the arrival of more effective interventions comes the need to end, or de-implement, less effective interventions. PURPOSE OF REVIEW: To describe the state of de-implementation research in HIV and provide a rationale for e...

journal_title：Current HIV/AIDS reports

authors： McKay VR,Tetteh EK,Reid MJ,Ingaiza LM

更新日期：2020-10-01 00:00:00