Metabolic Complications and Glucose Metabolism in HIV Infection: A Review of the Evidence.

Abstract:

:HIV infection and antiretroviral therapy (ART) use are associated with perturbations in glucose and lipid metabolism. Increasing incidence of diabetes, cardiovascular disease, and obesity highlights the need for early identification and treatment of metabolic dysfunction. Newer ART regimens are less toxic for cellular function and metabolism but have failed to completely eliminate metabolic dysfunction with HIV infection. Additional factors, including viral-host interactions, diet, physical activity, non-ART medications, and aging may further contribute to metabolic disease risk in the HIV setting. We summarize the recent literature regarding the impact on metabolic function of HIV infection, ART, and pharmaceutical or lifestyle prescriptions.

journal_name

Curr HIV/AIDS Rep

journal_title

Current HIV/AIDS reports

authors

Willig AL,Overton ET

doi

10.1007/s11904-016-0330-z

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

289-96

issue

5

eissn

1548-3568

issn

1548-3576

pii

10.1007/s11904-016-0330-z

journal_volume

13

pub_type

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