Therapeutic drug monitoring: pharmacologic considerations for antiretroviral drugs.

Abstract:

:Therapeutic drug monitoring (TDM) is the process by which a patient's dosing regimen is guided by repeated measures of plasma drug concentrations. An enormous challenge with regard to TDM of antiretroviral drugs (ARV) is that the concentration goals can be moving targets. Well-designed prospective studies demonstrating that prospectively altering ARV doses based on TDM leads to virologic success and increased tolerability are needed. Nevertheless, there are specific clinical instances where this experimental intervention should be considered to potentially reduce toxicity and improve therapeutic outcomes.

journal_name

Curr HIV/AIDS Rep

journal_title

Current HIV/AIDS reports

authors

Kiser JJ,Anderson PL,Gerber JG

doi

10.1007/s11904-005-0020-8

keywords:

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

61-7

issue

2

eissn

1548-3568

issn

1548-3576

journal_volume

2

pub_type

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