Solid organ transplantation is a reality for patients with HIV infection.

Abstract:

:Recent policies, guidelines, and laws reflect promising preliminary outcomes among transplant recipients with HIV infection, and ethical analyses suggest that it is not justifiable to deny solid organ transplantation based solely on HIV-infection status. These studies consistently describe stable HIV disease following liver and kidney transplantation. Despite good graft survival, kidney allograft rejection occurs frequently, and serious non-AIDS-defining infections requiring hospitalization are common following antirejection therapy. Profound interactions between immunosuppressants and antiretroviral drugs require careful monitoring, dose adjustment, and highly effective communication between the patient and a multidisciplinary group of health care providers. Despite these scientific and policy advances, many health care providers and patients remain unaware of ongoing progress in this field. The implications are critical, as late referral for liver transplant evaluation increases the pretransplant mortality risk. Because important patient selection and clinical management questions remain, it is critical that ongoing studies are completed quickly.

journal_name

Curr HIV/AIDS Rep

journal_title

Current HIV/AIDS reports

authors

Roland ME,Stock PG

doi

10.1007/BF02696657

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

132-8

issue

3

eissn

1548-3568

issn

1548-3576

journal_volume

3

pub_type

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