When Cancer Cells Are Given Lemo[NH3]s, They Make Lemo[NH3]ade.

Abstract:

:In normal physiology, end-products of metabolism are excreted from the body. In tumors, these metabolic wastes accumulate due to deregulated metabolism and vascular insufficiency. Spinelli et al. (2017) show that breast cancer cells adapt to ammonia buildup by recycling it for amino acid synthesis, which can support cancer cell growth.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Shan M,Lyssiotis CA

doi

10.1016/j.cmet.2017.11.008

subject

Has Abstract

pub_date

2017-12-05 00:00:00

pages

811-813

issue

6

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(17)30676-9

journal_volume

26

pub_type

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