Abstract:
:Global reduction in insulin signaling has been linked to extended life span in a range of organisms. New work on mice with brain-specific or whole-body reductions in insulin receptor substrate 2 (IRS2) (Taguchi et al., 2007) points to a role for insulin/IGF-1 signaling in the central control of mammalian aging.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Bartke Adoi
10.1016/j.cmet.2007.08.007subject
Has Abstractpub_date
2007-09-01 00:00:00pages
153-4issue
3eissn
1550-4131issn
1932-7420pii
S1550-4131(07)00229-Xjournal_volume
6pub_type
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