Aging: all in the head?

Abstract:

:Global reduction in insulin signaling has been linked to extended life span in a range of organisms. New work on mice with brain-specific or whole-body reductions in insulin receptor substrate 2 (IRS2) (Taguchi et al., 2007) points to a role for insulin/IGF-1 signaling in the central control of mammalian aging.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Bartke A

doi

10.1016/j.cmet.2007.08.007

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

153-4

issue

3

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(07)00229-X

journal_volume

6

pub_type

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