What's the Mtrr with your grandparents?

Abstract:

:Reduced folate levels can cause developmental defects and megaloblastic anemia. Padmanabhan et al. (2013) show that mutation in mice of a folate metabolism gene, Mtrr, which encodes for methionine synthase reductase, causes developmental defects not only in the mutant progeny, but also in genetically wild-type descendants for up to four generations.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Greer EL,Shi Y

doi

10.1016/j.cmet.2013.09.016

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

457-9

issue

4

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(13)00385-9

journal_volume

18

pub_type

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