From the Transcriptome to Electrophysiology: Searching for the Underlying Cause of Diabetes.

Abstract:

:Cells within the islet of Langerhans are heterogeneous. Camunas-Soler et al. (2020) implement a patch-seq technique to collect both transcriptomic and electrophysiological data from the same cell. By doing so, they discover new genes that correlate with functional heterogeneity and find that shifts in these correlations indicate β cell compensation in type 2 diabetes.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Kravets V,Benninger RKP

doi

10.1016/j.cmet.2020.04.012

subject

Has Abstract

pub_date

2020-05-05 00:00:00

pages

888-889

issue

5

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(20)30194-7

journal_volume

31

pub_type

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