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Dietary Fat Inflames CD4+ T Cell Memory in Obesity.

Abstract：

:T cells promote inflammation in obesity, but how metabolic stress associated with obesity alters T cell responses remains unclear. In this issue of Cell Metabolism,Mauro et al. (2017) demonstrate that saturated fatty acids directly increase effector-memory T cell formation by amplifying T cell antigen-receptor-induced PI3K/Akt signaling.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Chapman NM,Chi H

doi

10.1016/j.cmet.2017.02.012

subject

Has Abstract

pub_date

2017-03-07 00:00:00

pages

490-492

issue

3

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(17)30102-X

journal_volume

25

pub_type

评论,杂志文章

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