Abstract：
:Individuals with elevated LDL-cholesterol levels have an increased risk for cardiovascular disease. Despite lipid lowering strategies, however, a significant cardiovascular risk remains. Bekkering et al. show that monocytes from patients with familial hypercholesterolemia have a trained immunity phenotype and that lipid lowering with statins does not revert this pro-inflammatory phenotype.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Bekkering S,Stiekema LCA,Bernelot Moens S,Verweij SL,Novakovic B,Prange K,Versloot M,Roeters van Lennep JE,Stunnenberg H,de Winther M,Stroes ESG,Joosten LAB,Netea MG,Riksen NPdoi
10.1016/j.cmet.2019.05.014subject
Has Abstractpub_date
2019-07-02 00:00:00pages
1-2issue
1eissn
1550-4131issn
1932-7420pii
S1550-4131(19)30254-2journal_volume
30pub_type
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