Abstract：
:In this issue of Cell Metabolism, Du et al. (2019) describe how insulin-like growth factor 2 (IGF-2), a protein with structural similarity to insulin, induces an anti-inflammatory phenotype in maturing macrophages through reprogramming of their mitochondrial metabolism. These anti-inflammatory properties are maintained upon secondary stimulation and alleviate experimental autoimmune encephalomyelitis (EAE) in vivo.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Domínguez-Andrés J,Netea MGdoi
10.1016/j.cmet.2019.05.012subject
Has Abstractpub_date
2019-06-04 00:00:00pages
1240-1242issue
6eissn
1550-4131issn
1932-7420pii
S1550-4131(19)30252-9journal_volume
29pub_type
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