Abstract：
:Leptin signals the repletion of fat stores, acting in the CNS to permit energy utilization by a host of autonomic and neuroendocrine processes and to decrease feeding. While much recent research has focused on the leptin-regulated circuitry of the hypothalamic arcuate nucleus (ARC), the majority of brain leptin receptor (LepRb)-expressing neurons lie outside the ARC in other CNS regions known to modulate energy balance. Each set of LepRb neurons throughout the brain presumably mediates unique aspects of leptin action, and understanding the function for LepRb-expressing neurons throughout the brain represents a crucial next step in the study of energy homeostasis.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Myers MG Jr,Münzberg H,Leinninger GM,Leshan RLdoi
10.1016/j.cmet.2008.12.001subject
Has Abstractpub_date
2009-02-01 00:00:00pages
117-23issue
2eissn
1550-4131issn
1932-7420pii
S1550-4131(08)00386-0journal_volume
9pub_type
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