Abstract：
:The link between Akt activation and gluconeogenic repression remains unclear, despite many years of investigation and remarkable progress. Rodgers and colleagues now introduce us to the Clk2 kinase, an Akt substrate that can directly phosphorylate and inhibit PGC-1alpha, blunting hepatic glucose production.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Cantó C,Auwerx Jdoi
10.1016/j.cmet.2009.12.003subject
Has Abstractpub_date
2010-01-01 00:00:00pages
6-7issue
1eissn
1550-4131issn
1932-7420pii
S1550-4131(09)00377-5journal_volume
11pub_type
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