Purloined mechanisms of bacterial immunity can cure muscular dystrophy.

Abstract:

:Myriad strategies have been explored to compensate for the lack of dystrophin or to skip mutations that cause the lethal disease Duchenne muscular dystrophy (DMD). A new study shows that gene editing strategies used by bacteria can be applied in zygotes of a mouse model of DMD to correct the genetic defect that causes muscular dystrophy (Long et al., 2014).

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Tidball JG,Bertoni C

doi

10.1016/j.cmet.2014.11.011

subject

Has Abstract

pub_date

2014-12-02 00:00:00

pages

927-9

issue

6

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(14)00508-7

journal_volume

20

pub_type

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