Abstract：
:Exercise produces many beneficial effects on brain health, in part by increasing hippocampal BDNF levels; however, the mechanism underlying BDNF gene regulation remains unknown. In this issue of Cell Metabolism, Wrann et al. (2013) show that exercise induces hippocampal Bdnf expression by stimulating expression of FNDC5, the precursor of irisin, via the transcriptional complex PGC-1α/Errα.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Xu Bdoi
10.1016/j.cmet.2013.10.008subject
Has Abstractpub_date
2013-11-05 00:00:00pages
612-4issue
5eissn
1550-4131issn
1932-7420pii
S1550-4131(13)00420-8journal_volume
18pub_type
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