Abstract:
:Hormesis is an adaptive stress response implicated in longevity regulation. Schroeder et al. (2013) have now connected stress, epigenetic changes, and aging in yeast by showing that mitochondria-derived reactive oxygen species modulate the chromatin binding capacity of the histone demethylase Rph1p at subtelomeres, resulting in lifespan extension.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Mirisola MG,Longo VDdoi
10.1016/j.cmet.2013.05.015subject
Has Abstractpub_date
2013-06-04 00:00:00pages
812-813issue
6eissn
1550-4131issn
1932-7420pii
S1550-4131(13)00205-2journal_volume
17pub_type
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