Abstract:
:Humans exhibit remarkable interindividual variations in the concentration of small molecules found throughout the body, due in part to concurrent variations in each person's associated microbial communities. Recent studies have begun to uncover how microbes interface with their host during exposure to drugs, dietary compounds, and environmental toxicants, with broader implications regarding the causes and consequences of biochemical individuality. Progress in this area will likely be an essential component of personalized medicine and might be accelerated through the implementation of experimental designs and theoretical principles honed through decades of work in the fields of toxicology and pharmacology.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Patterson AD,Turnbaugh PJdoi
10.1016/j.cmet.2014.07.002subject
Has Abstractpub_date
2014-11-04 00:00:00pages
761-768issue
5eissn
1550-4131issn
1932-7420pii
S1550-4131(14)00310-6journal_volume
20pub_type
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