Asparagine and Glutamine: Co-conspirators Fueling Metastasis.

Abstract:

:Cancer cells frequently hijack normal metabolic pathways to promote their growth and metastasis. Two recent papers by Knott et al. (2018) and Pavlova et al. (2018) demonstrate that asparagine and glutamine work in concert to drive tumor growth and metastasis through modulation of cell survival, growth, and EMT regulatory pathways.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Luo M,Brooks M,Wicha MS

doi

10.1016/j.cmet.2018.04.012

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

947-949

issue

5

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(18)30255-9

journal_volume

27

pub_type

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