Steroids make you bigger? Fat chance says Myc.

Abstract:

:In flies, ecdysone integrates growth with developmental transitions by antagonizing insulin signaling, which links growth with nutritional status. Work in Developmental Cell (Delanoue et. al, 2010) finds that ecdysone represses the transcription factor Myc in the larval fat body to inhibit systemic growth, revealing a mechanism for such coordination.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Rajan A,Perrimon N

doi

10.1016/j.cmet.2010.06.003

subject

Has Abstract

pub_date

2010-07-07 00:00:00

pages

7-9

issue

1

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(10)00191-9

journal_volume

12

pub_type

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