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Of Mice Not Men? Actions of Interleukin-6 on Glucose Tolerance.

Abstract：

:In mice, interleukin-6 (IL-6) improves glucose tolerance via stimulation of glucagon-like peptide 1 (GLP-1) secretion. In this issue of Cell Metabolism, Lang Lehrskov et al. (2018) demonstrate that IL-6 infusion has GLP-1-dependent and -independent actions with opposing effects on glucose tolerance, resulting in an overall improvement in healthy male volunteers but no improvement in male patients with diabetes.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

McGlone ER,Tan TM

doi

10.1016/j.cmet.2018.05.013

subject

Has Abstract

pub_date

2018-06-05 00:00:00

pages

1157-1158

issue

6

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(18)30320-6

journal_volume

27

pub_type

评论,杂志文章

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