Abstract:
:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Chiba S,Wakabayashi T,Tachi Y,Takaki N,Terashima A,Okumura S,Yoshida Tdoi
10.1038/s41598-017-17100-ysubject
Has Abstractpub_date
2017-12-05 00:00:00pages
17270issue
1issn
2045-2322pii
10.1038/s41598-017-17100-yjournal_volume
7pub_type
杂志文章,已发布勘误abstract::The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases. The release of EVs by Trypanosoma cruzi, the causative agent of Chagas disease, has recently been described, with different protein cargoes including the MA...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44451
更新日期:2017-03-15 00:00:00
abstract::A dynamical system is controllable if by imposing appropriate external signals on a subset of its nodes, it can be driven from any initial state to any desired state in finite time. Here we study the impact of various network characteristics on the minimal number of driver nodes required to control a network. We find ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01067
更新日期:2013-01-01 00:00:00
abstract::The precision prediction of peptide retention time (RT) plays an increasingly important role in liquid chromatography-tandem mass spectrometry (LC-MS/MS) based proteomics. Owing to the high reproducibility of liquid chromatography, RT prediction provides promising information for both identification and quantification...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43959
更新日期:2017-03-17 00:00:00
abstract::Melatonin has antioxidant and scavenger effects in the cellular antioxidant system. This research investigated the protective effects and underlying mechanisms of melatonin action in porcine somatic cell nuclear transfer (SCNT) embryos. The results suggested that the developmental competence of porcine SCNT embryos wa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-11161-9
更新日期:2017-09-11 00:00:00
abstract::The lithium-sulfur battery, which offers a high energy density and is environmental friendly, is a promising next generation of rechargeable energy storage system. However, despite these attractive attributes, the commercialization of lithium-sulfur battery is primarily hindered by the parasitic reactions between the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-11922-6
更新日期:2017-09-12 00:00:00
abstract::The aim of this study was to fabricate a novel polymer-free everolimus-eluting stent with nanostructure using a femtosecond laser (FSL). The stent were coated with everolimus (EVL) using FSL and electrospinning processes. The surface was rendered hydrophobic, which negatively affected both platelet adhesion (82.1%) an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25629-9
更新日期:2018-05-09 00:00:00
abstract::Identification of low-abundance, low-molecular-weight native peptides using non-tryptic plasma has long remained an unmet challenge, leaving potential bioactive/biomarker peptides undiscovered. We have succeeded in efficiently removing high-abundance plasma proteins to enrich and comprehensively identify low-molecular...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79353-4
更新日期:2021-01-13 00:00:00
abstract::Machine learning methods provide powerful tools to map physical measurements to scientific categories. But are such methods suitable for discovering the ground truth about psychological categories? We use the science of emotion as a test case to explore this question. In studies of emotion, researchers use supervised ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77117-8
更新日期:2020-11-20 00:00:00
abstract::The structure, mechanism of action and copper stoichiometry of the transmembrane sensor domain of the plant ethylene receptor ETR1 and homologs have remained elusive, hampering the understanding on how the perception of the plant hormone ethylene is transformed into a downstream signal. We generated the first structur...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45189-w
更新日期:2019-06-20 00:00:00
abstract::RNA-binding proteins are key regulators of post-transcriptional processes such as alternative splicing and mRNA stabilization. Rbm24 acts as a regulator of alternative splicing in heart and skeletal muscle, and is essential for sarcomere assembly. Homozygous inactivation of Rbm24 in mice disrupts cardiac development a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64667-0
更新日期:2020-05-06 00:00:00
abstract::The hepatic asialoglycoprotein receptor (ASGP-R) is posttranslationally modified in the Golgi en route to the plasma membrane, where it mediates clearance of desialylated serum glycoproteins. It is known that content of plasma membrane-associated ASGP-R is decreased after ethanol exposure, although the mechanisms rema...
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pub_type: 杂志文章
doi:10.1038/srep17127
更新日期:2015-11-26 00:00:00
abstract::What's on the label is not what's in the bottle, from food products to herbal medicinal products (HMPs), economically-motivated biomaterials adulteration is a long-term problem affecting the food and drug industry. Accurate identification of the biomaterial ingredients in processed commodities is highly desirable. In ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05083-9
更新日期:2017-07-06 00:00:00
abstract::Upregulated Wnt/β-catenin signaling is associated with increased cancer cell resistance and cancer cell-elicited immunosuppression. In non-neoplastic immune cells, upregulated Wnt/β-catenin is, however, associated with either immunosuppression or immunostimulation. Therefore, it is difficult to predict the therapeutic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41182-5
更新日期:2019-03-18 00:00:00
abstract::Cellular therapies for liver diseases and in vitro models for drug testing both require functional human hepatocytes (Hum-H), which have unfortunately been limited due to the paucity of donor liver tissues. Human pluripotent stem cells (hPSCs) represent a promising and potentially unlimited cell source to derive Hum-H...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16884
更新日期:2015-11-23 00:00:00
abstract::Multi-drug resistant efflux transporters found in Blood-Brain Barrier (BBB) acts as a functional barrier, by pumping out most of the drugs into the blood. Previous studies showed focused ultrasound (FUS) induced microbubble oscillation can disrupt the BBB by loosening the tight junctions in the brain endothelial cells...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31201
更新日期:2016-08-11 00:00:00
abstract::Correlating data from different microscopy techniques holds the potential to discover new facets of signaling events in cellular biology. Here we report for the first time a hardware set-up capable of achieving simultaneous co-localized imaging of spatially correlated far-field super-resolution fluorescence microscopy...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-57885-z
更新日期:2020-01-24 00:00:00
abstract::DNA-directed RNA polymerase II (pol II) is composed of ten core and two dissociable subunits. The dissociable subcomplex is a heterodimer of Rpb4/Polr2d and Rpb7/Polr2g, which are encoded by RPB4/polr2d and RPB7/polr2g genes, respectively. Functional studies of Rpb4/Polr2d in yeast have revealed that Rpb4 plays a role...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70110-1
更新日期:2020-08-06 00:00:00
abstract::Platinum resistance is one of the most challenging problems in ovarian cancer treatment. High-throughput functional siRNA screening identified tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (TIE-1) as a gene that confers cells resistant to cisplatin. Conversely enforced over-expression of TIE-1 was va...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31069-2
更新日期:2018-09-04 00:00:00
abstract::Endothelial mesenchymal transition (EndMT) plays a critical role in the pathogenesis and progression of interstitial and perivascular fibrosis after acute myocardial infarction (AMI). Pigment epithelium-derived factor (PEDF) is shown to be a new therapeutic target owing to its protective role in cardiovascular disease...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41932
更新日期:2017-02-07 00:00:00
abstract::To report the efficacy and safety of large diameter scleral lenses and determine their suitability in Asian subjects with intractable ocular surface diseases. This prospective study enrolled intractable ocular surface diseases subjects with uncorrected visual acuity > counting finger but ≥ 0.3 logMAR and best-correcte...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82010-z
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abstract::Generating a protective and long-lasting immune response is the primary goal in the expanding field of immunotherapeutic research. In current study we designed an immunogenic bacteriophage- based vaccine to induce a cytotoxic T lymphocyte activity against a mice tumor model over-expressing HER2/neu. Bacteriophage λ di...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38371-z
更新日期:2019-02-18 00:00:00
abstract::Pachychoroid spectrum diseases have attracted increasing attention, though their pathophysiology has yet to be fully elucidated. In this study, we assessed the vascular diameters of vortex veins in pachychoroid spectrum diseases such as central serous chorioretinopathy (CSC), pachychoroid neovasculopathy without polyp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75789-w
更新日期:2020-11-11 00:00:00
abstract::Colistin remains one of the few antibiotics effective against multi-drug resistant (MDR) hospital pathogens, such as Klebsiella pneumoniae. Yet resistance to this last-line drug is rapidly increasing. Characterized mechanisms of colR in K. pneumoniae are largely due to chromosomal mutations in two-component regulators...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28199-y
更新日期:2018-06-29 00:00:00
abstract::MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity pneumonitis (CHP). Due to this, we evaluated the implication of MUC5B rs35705950 in antisynthetase syn...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58400-0
更新日期:2020-01-29 00:00:00
abstract::The ligand-induced dimerization of cell surface single-transmembrane receptors is essential for their activation. However, physiological molecules that inhibit their dimerization and activation have not been identified. ErbB3 dimerizes with ErbB2 upon binding of heregulin (HRG) to ErbB3, causing the ErbB2-catalyzed ty...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10107-5
更新日期:2017-09-12 00:00:00
abstract::Graphene oxide-iron oxide (GO-Fe3O4) nanocomposites were synthesised by co-precipitating iron salts onto GO sheets in basic solution. The results showed that formation of two distinct structures was dependent upon the GO loading. The first structure corresponds to a low GO loading up to 10 wt%, associated with the ben...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04594
更新日期:2014-04-04 00:00:00
abstract::The objective was to measure the association between badger culling and bovine tuberculosis (TB) incidents in cattle herds in three areas of England between 2013-2017 (Gloucestershire and Somerset) and 2015-2017 (Dorset). Farming industry-selected licensed culling areas were matched to comparison areas. A TB incident ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49957-6
更新日期:2019-10-11 00:00:00
abstract::Periconceptional supplementation with folic acid reduces the occurrence of neural tube defects (NTDs). The association between maternal abnormalities in homocysteine metabolism (e.g., hyperhomocysteinaemia, folate deficiency and low vitamin B12) and the risk of NTDs-affected pregnancies has been widely evaluated in re...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/srep08510
更新日期:2015-03-02 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-46785-6
更新日期:2019-07-17 00:00:00
abstract::The charge transport properties of hybrid halide perovskites are investigated with a combination of density functional theory including van der Waals interaction and the Boltzmann theory for diffusive transport in the relaxation time approximation. We find the mobility of electrons to be in the range 5-10 cm(2)V(-1)s(...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12746
更新日期:2015-08-03 00:00:00