Quantitative assessment of maternal biomarkers related to one-carbon metabolism and neural tube defects.

abstract：:Lactic acidosis is common in critical care; by contrast, a subtype called alcohol-associated lactic acidosis (AALA) is rarely encountered. The primary purpose of this study was to determine the prognosis of AALA in critically ill patients and the second aim was to determine whether the survival was associated to the p...

journal_title：Scientific reports

authors： Yang CC,Chan KS,Tseng KL,Weng SF

更新日期：2016-10-17 00:00:00

abstract：:Sustainable wastewater treatment has been attracting increasing attentions over the past decades. However, the production of nitrous oxide (N2O), a potent GHG, from the energy-efficient granule-based autotrophic nitrogen removal is largely unknown. This study applied a previously established N2O model, which incorpora...

journal_title：Scientific reports

authors： Peng L,Sun J,Liu Y,Dai X,Ni BJ

更新日期：2017-04-03 00:00:00

abstract：:Propofol sedation has been applied during esophagogastroduodenoscopy procedures, but whether topical pharyngeal anesthesia should be administered at the same time has rarely been reported. Our study examined the role of topical pharyngeal anesthesia in sedated endoscopies in a randomized controlled double-blinded clin...

journal_title：Scientific reports

authors： Sun X,Xu Y,Zhang X,Li A,Zhang H,Yang T,Liu Y

更新日期：2018-04-27 00:00:00

abstract：:The controllability of a network is a theoretical problem of relevance in a variety of contexts ranging from financial markets to the brain. Until now, network controllability has been characterized only on isolated networks, while the vast majority of complex systems are formed by multilayer networks. Here we build a...

journal_title：Scientific reports

authors： Menichetti G,Dall'Asta L,Bianconi G

更新日期：2016-02-12 00:00:00

abstract：:Microbial secondary metabolites are valuable resources for novel drug discovery. In particular, actinomycetes expressed a range of antibiotics against a spectrum of bacteria. In genus level, strain Allosalinactinospora lopnorensis CA15-2(T) is the first new actinomycete isolated from the Lop Nor region, China. Antimic...

journal_title：Scientific reports

authors： Huang C,Leung RK,Guo M,Tuo L,Guo L,Yew WW,Lou I,Lee SMY,Sun C

更新日期：2016-02-11 00:00:00

abstract：:It has been postulated that there is a link between age related degenerative diseases and cancer. The TNF-related apoptosis-inducing ligand (TRAIL) has been shown to selectively kill tumor cells by binding to pro-apoptotic and anti-apoptotic receptors. Our aim was to study the levels of anti-apoptotic receptor (DcR1) ...

journal_title：Scientific reports

authors： Anand A,Sharma NK,Singh R,Gupta A,Prabhakar S,Jindal N,Bhatt AK,Sharma SK,Gupta PK

更新日期：2014-02-18 00:00:00

abstract：:The atomic-scale response of dielectrics/ferroelectrics to electric fields is central to their functionality. Here we introduce an in situ characterization method that reveals changes in the local atomic structure in polycrystalline materials under fields. The method employs atomic pair distribution functions (PDFs), ...

journal_title：Scientific reports

authors： Usher TM,Levin I,Daniels JE,Jones JL

更新日期：2015-10-01 00:00:00

abstract：:Glass is an ultraviscous liquid that ceases to flow on a laboratory timescale but continues to relax on a geological timescale. Quintessentially, it has become hopeless for humans to explore the equilibrium behavior of glass, although the technology of glass making witness a remarkable advance. In this work, we propos...

journal_title：Scientific reports

authors： Tripathy SN,Rams-Baron M,Wojnarowska Z,Knapik-Kowalczuk J,Paluch M

更新日期：2017-02-22 00:00:00

abstract：:The rapid increase in the number of genetically modified (GM) varieties has led to a demand for high-throughput methods to detect genetically modified organisms (GMOs). We describe a new dynamic array-based high throughput method to simultaneously detect 48 targets in 48 samples on a Fludigm system. The test targets i...

journal_title：Scientific reports

authors： Li X,Wu Y,Li J,Li Y,Long L,Li F,Wu G

更新日期：2015-01-05 00:00:00

abstract：:Previous studies have evaluated gene expression in Alzheimer's disease (AD) brains to identify mechanistic processes, but have been limited by the size of the datasets studied. Here we have implemented a novel meta-analysis approach to identify differentially expressed genes (DEGs) in published datasets comprising 450...

journal_title：Scientific reports

authors： Li X,Long J,He T,Belshaw R,Scott J

更新日期：2015-07-23 00:00:00

abstract：:Human iPS cells hold great promise for disease modeling and treatment of degenerative disorders including muscular dystrophies. Although a few research groups have used them for skeletal muscle differentiation, most were based on gene over-expression or long-term mesenchymal differentiation and retrospective identific...

journal_title：Scientific reports

authors： Wu J,Hunt SD,Xue H,Liu Y,Darabi R

更新日期：2016-01-05 00:00:00

abstract：:In this work the chalcopyrite CuIn3Se5-xTex (x = 0~0.5) with space group through isoelectronic substitution of Te for Se have been prepared, and the crystal structure dilation has been observed with increasing Te content. This substitution allows the anion position displacement ∆u = 0.25-u to be zero at x ≈ 0.15. Howe...

journal_title：Scientific reports

authors： Lu Y,Chen S,Wu W,Du Z,Chao Y,Cui J

更新日期：2017-01-06 00:00:00

abstract：:Family studies have identified a heritable component to self-harm that is partially independent from comorbid psychiatric disorders. However, the genetic aetiology of broad sense (non-suicidal and suicidal) self-harm has not been characterised on the molecular level. In addition, controversy exists about the degree to...

journal_title：Scientific reports

authors： Campos AI,Verweij KJH,Statham DJ,Madden PAF,Maciejewski DF,Davis KAS,John A,Hotopf M,Heath AC,Martin NG,Rentería ME

更新日期：2020-06-16 00:00:00

abstract：:Myosin X (Myo10), an actin-associated molecular motor, has a clear role in filopodia induction and cell migration in vitro, but its role in vivo in mammals is not well understood. Here, we investigate the role of Myo10 in melanocyte lineage and melanoma induction. We found that Myo10 knockout (Myo10KO) mice exhibit a ...

journal_title：Scientific reports

authors： Tokuo H,Bhawan J,Coluccio LM

更新日期：2018-07-11 00:00:00

abstract：:The present study shows chronic adjustments in the myotendinous junction (MTJ) in response to different ladder-based resistance training (LRT) protocols. Thirty adult male Wistar rats were divided into groups: sedentary (S), calisthenics (LRT without additional load [C]), and resistance-trained (LRT with extra weight ...

journal_title：Scientific reports

authors： Pimentel Neto J,Rocha LC,Barbosa GK,Jacob CDS,Krause Neto W,Watanabe IS,Ciena AP

更新日期：2020-08-24 00:00:00

abstract：:This study evaluated the 4-year results of 32 patients with T1N0 low-lying rectal adenocarcinoma treated solely with californium-252 (Cf-252) neutron intracavity brachytherapy (ICBT). Patients were solicited into the study from January 2008 to June 2011. All the patients had refused surgery or surgery was contraindica...

journal_title：Scientific reports

authors： Xiong Y,Shan J,Liu J,Zhao K,Chen S,Xu W,Zhou Q,Yang M,Lei X

更新日期：2017-01-17 00:00:00

abstract：:Artificial interface anisotropy is demonstrated in alternating Co/Pt and Co/Pd stripe patterns, providing a means of forming magnetic anisotropy using lithography. In-plane hysteresis loops measured along two principal directions are explained in depth by two competing shape and interface anisotropies, thus confirming...

journal_title：Scientific reports

authors： Kim SN,Nam YJ,Kim YD,Choi JW,Lee H,Lim SH

更新日期：2016-05-24 00:00:00

abstract：:Angiogenesis plays a key role in several diseases including cancer, ischemic vascular disease, and Alzheimer's disease. Chemical genetic screening of endothelial tube formation provides a robust approach for identifying signalling components that impact microvascular network morphology as well as endothelial cell biol...

journal_title：Scientific reports

authors： Sailem HZ,Al Haj Zen A

更新日期：2020-08-14 00:00:00

abstract：:Harnessing complement-mediated cytotoxicity by therapeutic antibodies has been limited because of dependency on size and density of antigen, structural constraints resulting from orientation of antibody binding, and blockade of complement activation by inhibitors expressed on target cells. We developed a modular bispe...

journal_title：Scientific reports

authors： Cruz JW,Damko E,Modi B,Tu N,Meagher K,Voronina V,Gartner H,Ehrlich G,Rafique A,Babb R,Aneja P,Potocky TB,D' Orvilliers A,Coppi A,E SY,Qiu H,Williams CM,Bennett BL,Chen G,Macdonald L,Olson W,Lin JC,Stahl N,Mu

更新日期：2019-08-19 00:00:00

abstract：:While the worldwide standardization of agricultural production has been advocated and recommended, relatively little research has focused on the ecological significance of such a shift. The ecological concerns stemming from the standardization of agricultural production may require new methodology. In this study, we c...

journal_title：Scientific reports

authors： Wan NF,Zhang MY,Jiang JX,Ji XY,Hao-Zhang

更新日期：2016-02-22 00:00:00

abstract：:Invasive pulmonary Aspergillosis is a leading cause of morbidity and mortality in immunosuppressed patients and treatment outcomes using oral antifungal triazoles remain suboptimal. Here we show that combining topical treatment using PC945, a novel inhaled triazole, with systemic treatment using known triazoles demons...

journal_title：Scientific reports

authors： Colley T,Sehra G,Daly L,Kimura G,Nakaoki T,Nishimoto Y,Kizawa Y,Strong P,Rapeport G,Ito K

更新日期：2019-07-01 00:00:00

abstract：:Volcanic activity is often preceded or accompanied by different types of seismo-volcanic signals. Among these signals, the so-called tornillo (Spanish for "screw") events are considered to belong to a unique class of volcano-seismicity characterised by a long-duration coda, amplitude modulation and high-quality factor...

journal_title：Scientific reports

authors： Fazio M,Alparone S,Benson PM,Cannata A,Vinciguerra S

更新日期：2019-05-14 00:00:00

abstract：:Streptococcus mutans is known to be a major causative agent of dental caries, and strains expressing the cell surface collagen-binding Cnm protein contribute to the development of several systemic diseases. A relationship between tonsillar immunity and glomerulonephritis has been recognized in IgA nephropathy (IgAN), ...

journal_title：Scientific reports

authors： Ito S,Misaki T,Naka S,Wato K,Nagasawa Y,Nomura R,Otsugu M,Matsumoto-Nakano M,Nakano K,Kumagai H,Oshima N

更新日期：2019-12-27 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Sahani RM,Kumari C,Pandya A,Dixit A

更新日期：2020-02-19 00:00:00

abstract：:Humans, like all organisms, are subject to fundamental biophysical laws. Van Valen predicted that, because of zero-sum dynamics, all populations of all species in a given environment flux the same amount of energy on average. Damuth's 'energetic equivalence rule' supported Van Valen´s conjecture by showing a tradeoff ...

journal_title：Scientific reports

authors： Burger JR,Weinberger VP,Marquet PA

更新日期：2017-03-02 00:00:00

abstract：:Networks of protoplasmic tubes of organism Physarum polycehpalum are macro-scale structures which optimally span multiple food sources to avoid repellents yet maximize coverage of attractants. When data are presented by configurations of attractants and behaviour of the slime mould is tuned by a range of repellents, t...

journal_title：Scientific reports

authors： Whiting JG,Jones J,Bull L,Levin M,Adamatzky A

更新日期：2016-02-03 00:00:00

abstract：:The claim that organic agriculture produces higher levels of phytochemicals has been controversial for decades. Using strawberries as a model crop in field conditions, a preharvest leaf wounding stress was applied to study the production of phytochemicals in fruits. As a result phenolic compounds (PCs) and total solub...

journal_title：Scientific reports

authors： Ibanez F,Bang WY,Lombardini L,Cisneros-Zevallos L

更新日期：2019-12-17 00:00:00

abstract：:Arctic and alpine environments present extreme, but different, challenges to survival. We therefore studied the ecological adaptation of the arctic-alpine fritillary Boloria napaea in northern Sweden and compared these results with the eastern Alps. Using mark-release-recapture, we analysed phenology, mobility, activi...

journal_title：Scientific reports

authors： Ehl S,Holzhauer SIJ,Ryrholm N,Schmitt T

更新日期：2019-03-07 00:00:00

abstract：:Asbestos is a potent carcinogen associated with malignant mesothelioma and lung cancer but its carcinogenic mechanisms are still poorly understood. Asbestos toxicity is ascribed to its particular physico-chemical characteristics, and one of them is the presence of and ability to adsorb iron, which may cause an alterat...

journal_title：Scientific reports

authors： Pascolo L,Gianoncelli A,Schneider G,Salomé M,Schneider M,Calligaro C,Kiskinova M,Melato M,Rizzardi C

更新日期：2013-01-01 00:00:00

abstract：:In recent years artificial neural networks achieved performance close to or better than humans in several domains: tasks that were previously human prerogatives, such as language processing, have witnessed remarkable improvements in state of the art models. One advantage of this technological boost is to facilitate co...

journal_title：Scientific reports

authors： Alamia A,Gauducheau V,Paisios D,VanRullen R

更新日期：2020-12-17 00:00:00