Specific strains of Streptococcus mutans, a pathogen of dental caries, in the tonsils, are associated with IgA nephropathy.

abstract：:Antigen (Ag)-mediated crosslinking of IgE-loaded high-affinity receptors for IgE (FcεRI) on mast cells (MCs) triggers activation of proinflammatory effector functions relevant for IgE-associated allergic disorders. The cytosolic tyrosine kinase BTK and the SH2-containing inositol-5'-phosphatase SHIP1 are central posit...

journal_title：Scientific reports

authors： Zorn CN,Simonowski A,Huber M

更新日期：2018-10-19 00:00:00

abstract：:Direct bone marrow (BM) injection has been proposed as a strategy to bypass homing inefficiencies associated with intravenous (IV) hematopoietic stem cell (HSC) transplantation. Despite physical delivery into the BM cavity, many donor cells are rapidly redistributed by vascular perfusion, perhaps compromising efficacy...

journal_title：Scientific reports

authors： Futrega K,Lott WB,Doran MR

更新日期：2016-04-11 00:00:00

abstract：:Electrode materials which exhibit high conductivities in both oxidising and reducing atmospheres are in high demand for solid oxide fuel cells (SOFCs) and solid oxide electrolytic cells (SOECs). In this paper, we investigated Cu-doped SrFe0.9Nb0.1O3-δ finding that the primitive perovskite oxide SrFe0.8Cu0.1Nb0.1O3-δ (...

journal_title：Scientific reports

authors： Lan R,Cowin PI,Sengodan S,Tao S

更新日期：2016-08-22 00:00:00

abstract：:Ballooning degeneration (BD) of hepatocytes is a distinguishing histological feature associated with the progression of nonalcoholic fatty liver disease (NAFLD). Under the assumption that NAFLD severity is associated with metabolic-stress we explored the hypothesis that heat shock 27 kDa protein 1 (HSP27), a protein c...

journal_title：Scientific reports

authors： Sookoian S,Castaño GO,Scian R,San Martino J,Pirola CJ

更新日期：2016-03-03 00:00:00

abstract：:ADC is a potential post treatment imaging biomarker in colorectal liver metastasis however measurements are affected by respiratory motion. This is compounded by increased statistical uncertainty in ADC measurement with decreasing tumour volume. In this prospective study we applied a retrospective motion correction me...

journal_title：Scientific reports

authors： Pathak R,Tian J,Thacker NA,Morris DM,Ragheb H,Saunders C,Saunders M,Jackson A

更新日期：2019-03-07 00:00:00

abstract：:The proportion of women who experience a depressive state after delivery differs between primiparas and multiparas, so it is important to clarify the different factors related to depression between the two groups. In this study, we confirmed the differences in depressive states, the perinatal period, and social suppor...

journal_title：Scientific reports

authors： Nakamura Y,Okada T,Morikawa M,Yamauchi A,Sato M,Ando M,Ozaki N

更新日期：2020-10-13 00:00:00

abstract：:Studies investigating association of depression with overall survival (OS) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) yielded conflicting results. A nationwide cohort study, which included all adult patients [n = 7,170; depression group, 13.3% (N = 956); non-depression group, 86.7% (N = 6,214...

journal_title：Scientific reports

authors： Wang SM,Park SS,Park SH,Kim NY,Kang DW,Na HR,Lee JW,Han S,Lim HK

更新日期：2020-09-17 00:00:00

abstract：:Deforestation and forest degradation around the world endanger the functioning of ecosystems, climate stability, and conservation of biodiversity. We assessed the spatial and temporal dynamics of forest cover in Myanmar's Hkakabo Razi Landscape (HRL) to determine its integrity based on forest change and fragmentation ...

journal_title：Scientific reports

authors： Suarez-Rubio M,Connette G,Aung T,Kyaw M,Renner SC

更新日期：2020-08-19 00:00:00

abstract：:Cold atomic gases are perfect laboratories for realization of quantum simulators. In order to simulate solid state systems in the presence of magnetic fields special effort has to be made because atoms are charge neutral. There are different methods for realization of artificial magnetic fields, that is the creation o...

journal_title：Scientific reports

authors： Mochol M,Sacha K

更新日期：2015-01-08 00:00:00

abstract：:Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of these lines with their other properties. The analysis revealed a r...

journal_title：Scientific reports

authors： Zielinski DC,Jamshidi N,Corbett AJ,Bordbar A,Thomas A,Palsson BO

更新日期：2017-01-25 00:00:00

abstract：:The ability to form mineral structures under biological control is widespread among animals. In several species, specific proteins have been shown to be involved in biomineralization, but it is uncertain how they influence the shape of the growing biomineral and the resulting skeleton. Calcareous sponges are the only ...

journal_title：Scientific reports

authors： Voigt O,Adamska M,Adamski M,Kittelmann A,Wencker L,Wörheide G

更新日期：2017-04-13 00:00:00

abstract：:Pitch is a complex hearing phenomenon that results from elicited and self-generated cochlear vibrations. Read-off vibrational information is relayed higher up the auditory pathway, where it is then condensed into pitch sensation. How this can adequately be described in terms of physics has largely remained an open que...

journal_title：Scientific reports

authors： Martignoli S,Gomez F,Stoop R

更新日期：2013-01-01 00:00:00

abstract：:Millimeter wave (MMW)-induced heating represents a promising alternative for non-invasive hyperthermia of superficial skin cancer, such as melanoma. Pulsed MMW-induced heating of tumors allows for reaching high peak temperatures without overheating surrounding tissues. Herein, for the first time, we evaluate apoptotic...

journal_title：Scientific reports

authors： Orlacchio R,Le Page Y,Le Dréan Y,Le Guével R,Sauleau R,Alekseev S,Zhadobov M

更新日期：2019-10-24 00:00:00

abstract：:The hip fracture is one major clinical challenge associated with osteoporosis, resulting in heavy socioeconomic burdens and high mortality. Systemic therapies of anti-osteoporosis drugs are expensive, time-consuming and also evoke substantial side effects, which fails to provide early protection from fractures. Accumu...

journal_title：Scientific reports

authors： Jing D,Hao X,Xu F,Liu J,Xu F,Luo E,Meng G

更新日期：2016-06-22 00:00:00

abstract：:Solar conversion to fuels or to electricity in semiconductors using far red-to-near infrared (NIR) light, which accounts for about 40% of solar energy, is highly significant. One main challenge is the development of novel strategies for activity promotion and new basic mechanisms for NIR response. Mother Nature has ev...

journal_title：Scientific reports

authors： Yan R,Chen M,Zhou H,Liu T,Tang X,Zhang K,Zhu H,Ye J,Zhang D,Fan T

更新日期：2016-01-28 00:00:00

abstract：:Strongly coupled quantum dot-cavity systems provide a non-linear configuration of hybridized light-matter states with promising quantum-optical applications. Here, we investigate the coherent interaction between strong laser pulses and quantum dot-cavity polaritons. Resonant excitation of polaritonic states and their ...

journal_title：Scientific reports

authors： Dory C,Fischer KA,Müller K,Lagoudakis KG,Sarmiento T,Rundquist A,Zhang JL,Kelaita Y,Vučković J

更新日期：2016-04-26 00:00:00

abstract：:Alveolar β2-receptor blockade worsens lung diffusion in heart failure (HF). This effect could be mitigated by stimulating alveolar β2-receptors. We investigated the safety and the effects of indacaterol on lung diffusion, lung mechanics, sleep respiratory behavior, cardiac rhythm, welfare, and exercise performance in ...

journal_title：Scientific reports

authors： Contini M,Spadafora E,Barbieri S,Gugliandolo P,Salvioni E,Magini A,Apostolo A,Palermo P,Alimento M,Agostoni P

更新日期：2020-04-28 00:00:00

abstract：:Vapor-phase deposited polymer coatings are applied on thin indomethacin films to modify the drug release. Hydrogel-forming co-polymers of 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate were prepared directly on top of solution cast indomethacin thin films by initiated Chemical Vapor Deposition (iCVD). ...

journal_title：Scientific reports

authors： Christian P,Tumphart S,Ehmann HMA,Riegler H,Coclite AM,Werzer O

更新日期：2018-05-08 00:00:00

abstract：:During Antarctic isolation personnel are exposed to extreme photoperiods. A frequent observation is a sleep onset phase delay during winter. It is not known if, as a result, daytime sleeping in the form of naps increases. We sought to assess sleep patterns - with focus on daytime sleeping - and alertness in a Latin Am...

journal_title：Scientific reports

authors： Folgueira A,Simonelli G,Plano S,Tortello C,Cuiuli JM,Blanchard A,Patagua A,Brager AJ,Capaldi VF,Aubert AE,Barbarito M,Golombek DA,Vigo DE

更新日期：2019-07-26 00:00:00

abstract：:Kohlschutter-Tönz syndrome (KTS) is a rare genetic disorder with neurological dysfunctions including seizure and intellectual impairment. Mutations at the Rogdi locus have been linked to development of KTS, yet the underlying mechanisms remain elusive. Here we demonstrate that a Drosophila homolog of Rogdi acts as a n...

journal_title：Scientific reports

authors： Kim M,Jang D,Yoo E,Oh Y,Sonn JY,Lee J,Ki Y,Son HJ,Hwang O,Lee C,Lim C,Choe J

更新日期：2017-09-12 00:00:00

abstract：:Skin malignant melanoma is a highly angiogenic cancer, necessitating early diagnosis for positive prognosis. The current diagnostic standard of biopsy and histological examination inevitably leads to many unnecessary invasive excisions. Here, we propose a non-invasive method of identification of melanoma based on bloo...

journal_title：Scientific reports

authors： Lancaster G,Stefanovska A,Pesce M,Marco Vezzoni G,Loggini B,Pingitore R,Ghiara F,Barachini P,Cervadoro G,Romanelli M,Rossi M

更新日期：2015-08-11 00:00:00

abstract：:Planktonic foraminifera (PF) life cycles are highly sensitive to marine conditions, which are evolving rapidly due to anthropogenic climate change. Even though PF shells in the sedimentary record serve as prominent proxies of past ocean conditions, very little is still known about their life cycles, particularly in ol...

journal_title：Scientific reports

authors： Chernihovsky N,Almogi-Labin A,Kienast SS,Torfstein A

更新日期：2020-10-15 00:00:00

abstract：:The mosquito, Aedes baisasi, which inhabits brackish mangrove swamps, is known to feed on fish. However, its host assemblage has not been investigated at the species level. We amplified and sequenced the cytochrome oxidase subunit I barcoding regions as well as some other regions from blood-fed females to identify hos...

journal_title：Scientific reports

authors： Miyake T,Aihara N,Maeda K,Shinzato C,Koyanagi R,Kobayashi H,Yamahira K

更新日期：2019-03-08 00:00:00

abstract：:Support from human genetics increases the probability of success in drug development. However, few examples exist of successful genomically-driven drug repositioning. Given that a Mendelian form of severe enterocolitis is due to up-regulation of the interleukin-18 (IL18) signaling pathway, and pharmacologic inhibition...

journal_title：Scientific reports

authors： Mokry LE,Zhou S,Guo C,Scott RA,Devey L,Langenberg C,Wareham N,Waterworth D,Cardon L,Sanseau P,Davey Smith G,Richards JB

更新日期：2019-06-28 00:00:00

abstract：:Large bowel preparation may cause a substantial change in the gut microbiota and metabolites. Here, we included a bowel prep group and a no-procedure control group and evaluated the effects of bowel prep on the stability of the gut microbiome and metabolome as well as on recovery. Gut microbiota and metabolome composi...

journal_title：Scientific reports

authors： Nagata N,Tohya M,Fukuda S,Suda W,Nishijima S,Takeuchi F,Ohsugi M,Tsujimoto T,Nakamura T,Shimomura A,Yanagisawa N,Hisada Y,Watanabe K,Imbe K,Akiyama J,Mizokami M,Miyoshi-Akiyama T,Uemura N,Hattori M

更新日期：2019-03-11 00:00:00

abstract：:Caveolins are essential structural proteins driving the formation of caveolae, specialized invaginations of the plasma membrane. Loss of Caveolin-1 (Cav1) function in mice causes distinct neurological phenotypes leading to impaired motor control, however, the underlying developmental mechanisms are largely unknown. In...

journal_title：Scientific reports

authors： Breuer M,Berger H,Borchers A

更新日期：2020-10-05 00:00:00

abstract：:Decline in episodic memory performance usually causes the first clinical symptoms of Alzheimer's disease. At present, Alzheimer's disease can only be diagnosed at a very late stage when neurodegeneration and cognitive impairment is already irreversible. New early disease markers are needed for earlier and more efficie...

journal_title：Scientific reports

authors： Konki M,Lindgren N,Kyläniemi M,Venho R,Laajala E,Ghimire B,Lahesmaa R,Kaprio J,Rinne JO,Lund RJ

更新日期：2020-08-25 00:00:00

abstract：:Cardiorenal syndrome is defined by primary heart failure conditions influencing or leading to renal injury or dysfunction. Dilated cardiomyopathy (DCM) is a major co-existing form of heart failure (HF) with renal diseases. Myocardin (MYOCD), a cardiac-specific co-activator of serum response factor (SRF), is increased ...

journal_title：Scientific reports

authors： Mittal A,Rana S,Sharma R,Kumar A,Prasad R,Raut SK,Sarkar S,Saikia UN,Bahl A,Dhandapany PS,Khullar M

更新日期：2019-04-10 00:00:00

abstract：:Broadband acoustic absorbers with thin thickness are highly desired in practical situations such as architectural acoustics, yet it is still challenging to achieve high absorption by using structure with limited thickness. Here we report the theoretical optimal design, numerical simulation and experimental demonstrati...

journal_title：Scientific reports

authors： Gao YX,Lin YP,Zhu YF,Liang B,Yang J,Yang J,Cheng JC

更新日期：2020-07-01 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Lee DB,Kim JM,Seok JH,Lee JH,Jo JD,Mun JY,Conrad C,Coe J,Nelson G,Hogue B,White TA,Zatsepin N,Weierstall U,Barty A,Chapman H,Fromme P,Spence J,Chung MS,Oh CH,Kim KH

更新日期：2018-04-17 00:00:00