Author Correction: Supersaturation-controlled microcrystallization and visualization analysis for serial femtosecond crystallography.

abstract：:Many basic properties of the T-cell receptor (TCR) repertoire require clarification, and the changes occurring in the TCR repertoire during carcinogenesis, especially during precancerous stages, remain unclear. This study used deep sequencing analyses to examine 41 gastric tissue samples at different pathological stag...

journal_title：Scientific reports

authors： Kuang M,Cheng J,Zhang C,Feng L,Xu X,Zhang Y,Zu M,Cui J,Yu H,Zhang K,Yang A,Cheng S

更新日期：2017-08-10 00:00:00

abstract：:Glucocorticoids (GC) display pleiotropic effects on the immune system. Macrophages are a major target for GC action. Here we show that dexamethasone (DEX), a synthetic GC, decreased viability of naïve bone marrow-derived macrophages (BMDM), involving an apoptotic mechanism. Administration of DEX together with lipopoly...

journal_title：Scientific reports

authors： Haim YO,Unger ND,Souroujon MC,Mittelman M,Neumann D

更新日期：2014-03-10 00:00:00

abstract：:Graphene plasmonics has become a highlighted research area due to the outstanding properties of deep-subwavelength plasmon excitation, long relaxation time, and electro-optical tunability. Although the giant conductivity of a graphene layer enables the low-dimensional confinement of light, the atomic scale of the laye...

journal_title：Scientific reports

authors： Kim Y,Yu S,Park N

更新日期：2017-02-27 00:00:00

abstract：:Medial arterial calcification (MAC) is a common outcome in diabetes and chronic kidney disease (CKD). It occurs as linear mineral deposits along the degraded elastin lamellae and is responsible for increased aortic stiffness and subsequent cardiovascular events. Current treatments for calcification, particularly in CK...

journal_title：Scientific reports

authors： Karamched SR,Nosoudi N,Moreland HE,Chowdhury A,Vyavahare NR

更新日期：2019-02-22 00:00:00

abstract：:Nanoparticles are widely used in commodities, and pregnant women are inevitably exposed to these particles. The placenta protects the growing fetus from foreign or toxic materials, and provides energy and oxygen. Here we report that autophagy, a cellular mechanism to maintain homeostasis, engulfs platinum nanoparticle...

journal_title：Scientific reports

authors： Nakashima A,Higashisaka K,Kusabiraki T,Aoki A,Ushijima A,Ono Y,Tsuda S,Shima T,Yoshino O,Nagano K,Yoshioka Y,Tsutsumi Y,Saito S

更新日期：2019-04-02 00:00:00

abstract：:Seed setting is an important trait that contributes to seed yield and relies greatly on starch accumulation. In this study, a sulfoquinovosyl transferase-like protein, designated as SQD2.2 involved in seed setting and flavonoid accumulation, was identified and characterized in rice. Rice SQD2.2 is localized to the cyt...

journal_title：Scientific reports

authors： Zhan X,Shen Q,Wang X,Hong Y

更新日期：2017-07-05 00:00:00

abstract：:Unexpected reactor accidents and radioisotope production and consumption have led to a continuous increase in the global-scale contamination of radionuclides. In particular, anthropogenic radioiodine has become critical due to its highly volatile mobilization and recycling in global environments, resulting in widespre...

journal_title：Scientific reports

authors： Lee SY,Lee JY,Min JH,Kim SS,Baik MH,Chung SY,Lee M,Lee Y

更新日期：2016-06-17 00:00:00

abstract：:Investigation of quantum spin Hall states in 1T' phase of the monolayer transition metal dichalcogenides has recently attracted the attention for its potential in nanoelectronic applications. While most of the theoretical findings in this regard deal with infinitely periodic crystal structures, here we employ density ...

journal_title：Scientific reports

authors： Das B,Sen D,Mahapatra S

更新日期：2020-04-21 00:00:00

abstract：:Annually averaged solar radiation in the McMurdo Dry Valleys, Antarctica has varied by over 20 W m-2 during the past three decades; however, the drivers of this variability are unknown. Because small differences in radiation are important to water availability and ecosystem functioning in polar deserts, determining th...

journal_title：Scientific reports

authors： Obryk MK,Fountain AG,Doran PT,Lyons WB,Eastman R

更新日期：2018-03-22 00:00:00

abstract：:Immune checkpoint inhibitors (ICIs) elicit antitumour effects by activating the host immunity and cause immune-related adverse events (irAEs). ICI-related interstitial lung disease (ICI-ILD) is a fatal irAE that is difficult to treat; moreover, its incidence is relatively higher in patients with lung cancer. Therefore...

journal_title：Scientific reports

authors： Okada N,Matsuoka R,Sakurada T,Goda M,Chuma M,Yagi K,Zamami Y,Nishioka Y,Ishizawa K

更新日期：2020-08-13 00:00:00

abstract：:The tissue microenvironment is a major contributor to cellular functions, such as cell adhesion, migration and invasion. A critical physical parameter for determining the effect of the microenvironment on cellular functions is the average pore-size of filamentous scaffolds, such as 3D collagen fiber matrices, which ar...

journal_title：Scientific reports

authors： Fischer T,Hayn A,Mierke CT

更新日期：2019-06-07 00:00:00

abstract：:The IκB kinase (IKK) complex acts as the gatekeeper of canonical NF-κB signaling, thereby regulating immunity, inflammation and cancer. It consists of the catalytic subunits IKKα and IKKβ and the regulatory subunit NEMO/IKKγ. Here, we show that the ubiquitin binding domain (UBAN) in NEMO is essential for IKK/NF-κB act...

journal_title：Scientific reports

authors： Vincendeau M,Hadian K,Messias AC,Brenke JK,Halander J,Griesbach R,Greczmiel U,Bertossi A,Stehle R,Nagel D,Demski K,Velvarska H,Niessing D,Geerlof A,Sattler M,Krappmann D

更新日期：2016-01-07 00:00:00

abstract：:The preparation of mesoporous iron oxides with controllable physiochemical properties for effective therapeutic drug delivery remains a formidable challenge. Herein, iron oxide mesoporous magnetic microparticles (IO-MMMs) were prepared by a modified reverse hard-templating approach using, for the first time, acid-prep...

journal_title：Scientific reports

authors： El-Boubbou K,Ali R,Al-Zahrani H,Trivilegio T,Alanazi AH,Khan AL,Boudjelal M,AlKushi A

更新日期：2019-07-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) regulate hard tissue formation, including bone and tooth. Growth differentiation factor 5 (GDF5), a known BMP, is expressed in cartilage and regulates chondrogenesis, and mutations have been shown to cause osteoarthritis. Notably, GDF5 is also expressed in periodontal ligament tissue...

journal_title：Scientific reports

authors： Liu J,Saito K,Maruya Y,Nakamura T,Yamada A,Fukumoto E,Ishikawa M,Iwamoto T,Miyazaki K,Yoshizaki K,Ge L,Fukumoto S

更新日期：2016-03-31 00:00:00

abstract：:The Martian outflow channels comprise some of the largest known channels in the Solar System. Remote-sensing investigations indicate that cataclysmic floods likely excavated the channels ~3.4 Ga. Previous studies show that, in the southern circum-Chryse region, their flooding pathways include hundreds of kilometers of...

journal_title：Scientific reports

authors： Rodriguez JAP,Baker VR,Liu T,Zarroca M,Travis B,Hui T,Komatsu G,Berman DC,Linares R,Sykes MV,Banks ME,Kargel JS

更新日期：2019-02-25 00:00:00

abstract：:The 14-3-3-related protein SMG7 plays critical roles in regulation of DNA damage response and nonsense-mediated mRNA decay (NMD). Like 14-3-3, SMG7 engages phosphoserine-dependent protein interactions; however, the precise role of phosphorylation-mediated SMG7 binding remains unknown. Here, we show that DNA damage-ind...

journal_title：Scientific reports

authors： Cowen LE,Luo H,Tang Y

更新日期：2019-09-11 00:00:00

abstract：:The myxozoan parasite, Tetracapsuloides bryosalmonae has a two-host life cycle alternating between freshwater bryozoans and salmonid fish. Infected fish can develop Proliferative Kidney Disease, characterised by a gross lymphoid-driven kidney pathology in wild and farmed salmonids. To facilitate an in-depth understand...

journal_title：Scientific reports

authors： Faber M,Shaw S,Yoon S,de Paiva Alves E,Wang B,Qi Z,Okamura B,Hartikainen H,Secombes CJ,Holland JW

更新日期：2021-01-25 00:00:00

abstract：:Argininosuccinate synthetase 1 (ASS1) is the key enzyme that controls biosynthesis of arginine (Arg). ASS1 is silenced in many human malignancies therefore, these tumors require extracellular Arg for growth. The Arg-degrading recombinant protein, pegylated arginine deiminase (ADI-PEG20), has been in clinical trials fo...

journal_title：Scientific reports

authors： Tsai WB,Long Y,Chang JT,Savaraj N,Feun LG,Jung M,Chen HHW,Kuo MT

更新日期：2017-09-07 00:00:00

abstract：:Acquisition of nutrients during intra-vacuolar growth of L. pneumophila within macrophages or amoebae is poorly understood. Since many genes of L. pneumophila are acquired by inter-kingdom horizontal gene transfer from eukaryotic hosts, we examined the presence of human solute carrier (SLC)-like transporters in the L....

journal_title：Scientific reports

authors： Best A,Jones S,Abu Kwaik Y

更新日期：2018-05-29 00:00:00

abstract：:Inflammation is considered as a major contributor to brain injury following cerebral ischemia. The therapeutic potential of both MLC601/MLC901, which are herbal extract preparations derived from Chinese Medicine, has been reported both in advanced stroke clinical trials and also in animal and cellular models. The aim ...

journal_title：Scientific reports

authors： Widmann C,Gandin C,Petit-Paitel A,Lazdunski M,Heurteaux C

更新日期：2018-12-24 00:00:00

abstract：:It is essential to understand how the loss of biodiversity impacts both ecosystem function (EF) and multifunctionality (EMF). Previous studies have mostly focused on predicting how species richness (SR) impacts EMF, while the effect of functional diversity (FD) on EMF remains unclear. Specifically, we know little abou...

journal_title：Scientific reports

authors： Huang X,Su J,Li S,Liu W,Lang X

更新日期：2019-05-06 00:00:00

abstract：:Phosphoinositides play important roles in numerous intracellular membrane pathways. Little is known about the regulation or function of these lipids in rod photoreceptor cells, which have highly active membrane dynamics. Using new assays with femtomole sensitivity, we determined that whereas levels of phosphatidylinos...

journal_title：Scientific reports

authors： He F,Agosto MA,Anastassov IA,Tse DY,Wu SM,Wensel TG

更新日期：2016-06-01 00:00:00

abstract：:In this study, a novel resorufin thionocarbonate-based Hg2+-selective signaling probe (RT) for microfluidic paper-based analytical device (μPAD) applications is reported. The designed probe, RT, was readily synthesized by the one-step reaction of resorufin with phenyl thionochloroformate. The RT probe displayed a prom...

journal_title：Scientific reports

authors： Choi MG,Park SY,Park KY,Chang SK

更新日期：2019-03-04 00:00:00

abstract：:Topical anesthetics are widely applied in order to relieve the discomfort and anxiety caused by needle insertion and other painful superficial interventions at the oral cavity. So far, there are no commercially available effective topical anesthetic formulations for that purpose, and the most of developments are relat...

journal_title：Scientific reports

authors： Ribeiro LNM,Franz-Montan M,Alcântara ACS,Breitkreitz MC,Castro SR,Guilherme VA,Muniz BV,Rodrigues da Silva GH,de Paula E

更新日期：2020-07-09 00:00:00

abstract：:Infected dogs are the main reservoir of zoonotic visceral leishmaniasis, a widespread parasitic disease caused by Leishmania infantum. Therefore, the control of canine infections is required to reduce the incidence of human cases. Disease outcome in dogs depends on the fine balance between parasite virulence and effic...

journal_title：Scientific reports

authors： Olías-Molero AI,Corral MJ,Jiménez-Antón MD,Alunda JM

更新日期：2019-12-09 00:00:00

abstract：:Arachidonic acid (AA) is metabolized to diverse bioactive lipid mediators. Whereas the 5-lipoxygenase-activating protein (FLAP) facilitates AA conversion by 5-lipoxygenase (5-LOX) to pro-inflammatory leukotrienes (LTs), the soluble epoxide hydrolase (sEH) degrades anti-inflammatory epoxyeicosatrienoic acids (EETs). Ac...

journal_title：Scientific reports

authors： Garscha U,Romp E,Pace S,Rossi A,Temml V,Schuster D,König S,Gerstmeier J,Liening S,Werner M,Atze H,Wittmann S,Weinigel C,Rummler S,Scriba GK,Sautebin L,Werz O

更新日期：2017-08-24 00:00:00

abstract：:We investigated clinical associations of ficolins and mannose-binding lectin (MBL) in 157 patients suffering from acute myeloid leukaemia (AML). Concentrations of ficolin-1, ficolin-2, ficolin-3 and MBL (before chemotherapy) in serum were determined as were selected polymorphisms of the corresponding genes (FCN1, FCN2...

journal_title：Scientific reports

authors： Sokołowska A,Świerzko AS,Gajek G,Gołos A,Michalski M,Nowicki M,Szala-Poździej A,Wolska-Washer A,Brzezińska O,Wierzbowska A,Jamroziak K,Kowalski ML,Thiel S,Matsushita M,Jensenius JC,Cedzyński M

更新日期：2020-06-29 00:00:00

abstract：:A novel marine strain representing efficient degradation ability toward brown algae was isolated, identified, and assigned to Bacillus weihaiensis Alg07. The alga-associated marine bacteria promote the nutrient cycle and perform important functions in the marine ecosystem. The de novo sequencing of the B. weihaiensis ...

journal_title：Scientific reports

authors： Zhu Y,Chen P,Bao Y,Men Y,Zeng Y,Yang J,Sun J,Sun Y

更新日期：2016-11-30 00:00:00

abstract：:The General Unified Threshold model for Survival (GUTS) integrates previously published toxicokinetic-toxicodynamic models and estimates survival with explicitly defined assumptions. Importantly, GUTS accounts for time-variable exposure to the stressor. We performed three studies to test the ability of GUTS to predict...

journal_title：Scientific reports

authors： Ashauer R,Albert C,Augustine S,Cedergreen N,Charles S,Ducrot V,Focks A,Gabsi F,Gergs A,Goussen B,Jager T,Kramer NI,Nyman AM,Poulsen V,Reichenberger S,Schäfer RB,Van den Brink PJ,Veltman K,Vogel S,Zimmer EI,Preuss

更新日期：2016-07-06 00:00:00

abstract：:The search for green and sustainable modification method to produce durable bamboo materials remains a challenge in industry. Here, heat treatment in tung oil at 100-200 °C was employed to modify bamboo materials. Oil permeation and distribution in the structure of bamboo samples during heat treatment were explored. T...

journal_title：Scientific reports

authors： Tang T,Zhang B,Liu X,Wang W,Chen X,Fei B

更新日期：2019-09-06 00:00:00