The Sulfoquinovosyltransferase-like Enzyme SQD2.2 is Involved in Flavonoid Glycosylation, Regulating Sugar Metabolism and Seed Setting in Rice.

abstract：:Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the elderly. Zinc (Zn) ion interacts with the pathogenic hallmark, amyloid-β (Aβ), and is enriched in senile plaques in brain of AD patients. To understand Zn-chelated Aβ (ZnAβ) species, here we systematically characterized ZnAβ aggregates by ...

journal_title：Scientific reports

authors： Lee MC,Yu WC,Shih YH,Chen CY,Guo ZH,Huang SJ,Chan JCC,Chen YR

更新日期：2018-03-19 00:00:00

abstract：:Synchrotron X-ray imaging technique has been used to investigate biofluid flows in a non-destructive manner. This study aims to investigate the feasibility of the X-ray PIV technique with CO2 microbubbles as flow tracer for measurement of pulsatile blood flows under in vivo conditions. The traceability of CO2 microbub...

journal_title：Scientific reports

authors： Park H,Yeom E,Seo SJ,Lim JH,Lee SJ

更新日期：2015-03-06 00:00:00

abstract：:Patients with stress-induced exhaustion disorder (SED) demonstrate cognitive dysfunction similar to patients with minor traumatic brain injury (TBI). We have previously detected elevated concentrations of astrocyte-derived extracellular vesicles (EVs) in patients with TBI. As such, we hypothesized that astrocyte-deriv...

journal_title：Scientific reports

authors： Wallensten J,Nager A,Åsberg M,Borg K,Beser A,Wilczek A,Mobarrez F

更新日期：2021-01-21 00:00:00

abstract：:Although 3,5,3'-triiodothyronine (T3) is considered to be the primary bioactive thyroid hormone (TH) due to its high affinity for TH nuclear receptors (TRs), new data suggest that 3,5-diiodothyronine (T2) can also regulate transcriptional networks. To determine the functional relevance of these bioactive THs, RNA-seq ...

journal_title：Scientific reports

authors： Olvera A,Martyniuk CJ,Buisine N,Jiménez-Jacinto V,Sanchez-Flores A,Sachs LM,Orozco A

更新日期：2017-11-08 00:00:00

abstract：:The development and maturation of cortical circuits relies on the coordinated actions of long and short range axonal guidance cues. In this regard, the class 3 semaphorins and their receptors have been seen to be involved in the development and maturation of the hippocampal connections. However, although the role of m...

journal_title：Scientific reports

authors： Mata A,Gil V,Pérez-Clausell J,Dasilva M,González-Calixto MC,Soriano E,García-Verdugo JM,Sanchez-Vives MV,Del Río JA

更新日期：2018-01-22 00:00:00

abstract：:Tissue adhesion is a common complication after surgery. In this work, a dexamethasone loaded polymeric micelles in thermosensitive hydrogel composite (Dex hydrogel) was prepared, which combined the anti-adhesion barrier with controlled release of anti-adhesion drug. Dexamethasone (Dex) was encapsulated in polymeric mi...

journal_title：Scientific reports

authors： Wu Q,Wang N,He T,Shang J,Li L,Song L,Yang X,Li X,Luo N,Zhang W,Gong C

更新日期：2015-09-01 00:00:00

abstract：:Peripheral blood indices of systemic inflammation such as the neutrophil-lymphocyte ratio (NLR) have been shown to be prognostic in various cancers. We aim to investigate the clinical significance of these indices in patients with soft tissue sarcoma (STS). Seven hundred and twelve patients with available blood counts...

journal_title：Scientific reports

authors： Chan JY,Zhang Z,Chew W,Tan GF,Lim CL,Zhou L,Goh WL,Poon E,Somasundaram N,Selvarajan S,Sittampalam K,Chin F,Teh J,Tan MH,Soo KC,Teo M,Farid M,Quek R

更新日期：2018-08-10 00:00:00

abstract：:Climate can modulate human health at large spatial scales, but the influence of global, regional, and local environments remains poorly understood, especially for neglected diseases, such as mycoses. In this work, we present the correlation between climatic variables and hospitalizations for mycoses in Brazilian state...

journal_title：Scientific reports

authors： Silva FB,Santos JRN,da Silva LC,Gomes WC,Villis PCM,Gomes EDS,Pinheiro EAD,Azevedo CMPES,Dias RDS,Monteiro CA,Santos JRA

更新日期：2019-05-06 00:00:00

abstract：:Channelopathy mutations prove informative on disease causing mechanisms and channel gating dynamics. We have identified a novel heterozygous mutation in the KCNA1 gene of a young proband displaying typical signs and symptoms of Episodic Ataxia type 1 (EA1). This mutation is in the S4 helix of the voltage-sensing domai...

journal_title：Scientific reports

authors： Hasan S,Bove C,Silvestri G,Mantuano E,Modoni A,Veneziano L,Macchioni L,Hunter T,Hunter G,Pessia M,D'Adamo MC

更新日期：2017-07-04 00:00:00

abstract：:ABX464 is a first-in-class, clinical-stage, small molecule for oral administration that has shown strong anti-inflammatory effects in the DSS-model for inflammatory bowel disease (IBD) and also prevents replication of the HIV virus. ABX464 which binds to cap binding complex (CBC) has demonstrated safety and efficacy i...

journal_title：Scientific reports

authors： Vautrin A,Manchon L,Garcel A,Campos N,Lapasset L,Laaref AM,Bruno R,Gislard M,Dubois E,Scherrer D,Ehrlich JH,Tazi J

更新日期：2019-01-28 00:00:00

abstract：:Metals can transmit light by tunnelling when they possess skin-depth thickness. Tunnelling can be resonantly enhanced if resonators are added to each side of a metal film, such as additional dielectric layers or periodic structures on a metal surface. Here we show that, even with no additional resonators, tunnelling r...

journal_title：Scientific reports

authors： Kang JH,Park QH

更新日期：2013-01-01 00:00:00

abstract：:High Resolution Melt (HRM) is a versatile and rapid post-PCR DNA analysis technique primarily used to differentiate sequence variants among only a few short amplicons. We recently developed a one-vs-one support vector machine algorithm (OVO SVM) that enables the use of HRM for identifying numerous short amplicon seque...

journal_title：Scientific reports

authors： Fraley SI,Athamanolap P,Masek BJ,Hardick J,Carroll KC,Hsieh YH,Rothman RE,Gaydos CA,Wang TH,Yang S

更新日期：2016-01-18 00:00:00

abstract：:Unlike individual, free-floating planktonic bacteria, biofilms are surface-attached communities of slow- or non-replicating bacteria encased within a protective extracellular polymeric matrix enabling persistent bacterial populations to tolerate high concentrations of antimicrobials. Our current antibacterial arsenal ...

journal_title：Scientific reports

authors： Yang H,Abouelhassan Y,Burch GM,Kallifidas D,Huang G,Yousaf H,Jin S,Luesch H,Huigens RW

更新日期：2017-05-17 00:00:00

abstract：:Clinical data from 172 cases of uterine fibroids with different appearances on MRI-T2WI and accepted ultrasound guided high intensity focused ultrasound (USgHIFU) treatment were retrospectively analyzed. This study aimed to evaluate the clinical safety and efficacy of ablating different types of fibroids, classified b...

journal_title：Scientific reports

authors： Zhao WP,Zhang J,Han ZY,Yao JP,Zhou X,Liang P

更新日期：2017-09-07 00:00:00

abstract：:We assessed the association between depression status and prevalent and incident type 2 diabetes (T2D) as well as the interaction between depression and a genetic risk score (GS) based on 20 T2D single-nucleotide polymorphisms (SNPs) in a multi-ethnic longitudinal study. We studied 17,375 participants at risk for dysg...

journal_title：Scientific reports

authors： Garasia S,Samaan Z,Gerstein HC,Engert JC,Mohan V,Diaz R,Anand SS,Meyre D

更新日期：2017-05-09 00:00:00

abstract：:The auditory steady-state response (ASSR) has been used to detect auditory processing deficits in patients with psychiatric disorders. However, the methodology of ASSR recording from the brain surface has not been standardized in preclinical studies, limiting its use as a translational biomarker. The sites of maximal ...

journal_title：Scientific reports

authors： Kozono N,Honda S,Tada M,Kirihara K,Zhao Z,Jinde S,Uka T,Yamada H,Matsumoto M,Kasai K,Mihara T

更新日期：2019-06-11 00:00:00

abstract：:Although collateral vessel growth is distinctly enhanced by elevated fluid shear stress (FSS), the underlying regulatory mechanism of this process remains incompletely understood. Recent studies have shown that microRNAs (miRNAs) play a pivotal role in vascular development, homeostasis and a variety of diseases. There...

journal_title：Scientific reports

authors： Guan Y,Cai B,Wu X,Peng S,Gan L,Huang D,Liu G,Dong L,Xiao L,Liu J,Zhang B,Cai WJ,Schaper J,Schaper W

更新日期：2017-07-27 00:00:00

abstract：:High-resolution spectroscopy in the 1-10 μm region has never been fully tackled for the lack of widely-tunable and practical light sources. Indeed, all solutions proposed thus far suffer from at least one of three issues: they are feasible only in a narrow spectral range; the power available for spectroscopy is limite...

journal_title：Scientific reports

authors： Insero G,Borri S,Calonico D,Pastor PC,Clivati C,D'Ambrosio D,De Natale P,Inguscio M,Levi F,Santambrogio G

更新日期：2017-10-06 00:00:00

abstract：:Boiling histotripsy (BH) is a High Intensity Focused Ultrasound (HIFU) method for precise mechanical disintegration of target tissue using millisecond-long pulses containing shocks. BH treatments with real-time ultrasound (US) guidance allowed by BH-generated bubbles were previously demonstrated ex vivo and in vivo in...

journal_title：Scientific reports

authors： Khokhlova TD,Schade GR,Wang YN,Buravkov SV,Chernikov VP,Simon JC,Starr F,Maxwell AD,Bailey MR,Kreider W,Khokhlova VA

更新日期：2019-12-27 00:00:00

abstract：:More and more researchers are interested in and focused on how a limited repertoire of antibodies can bind and correspondingly protect against an almost limitless diversity of invading antigens. In this work, a series of 200-ns molecular dynamics (MD) simulations followed by principal component (PC) analysis and free ...

journal_title：Scientific reports

authors： Chen J,Wang J,Zhu W

更新日期：2016-11-10 00:00:00

abstract：:In this study, novel ZnS@In2S3 core@shell hollow nanospheres were fabricated by a facile refluxing method for the first time, and the formation mechanism of hollow structure with interior architecture was discussed based on ion-exchange Ostwald ripening. As the photocatalytic material for degradation of gaseous o-Dich...

journal_title：Scientific reports

authors： Liu B,Hu X,Li X,Li Y,Chen C,Lam KH

更新日期：2017-11-27 00:00:00

abstract：:Melatonin has antioxidant and scavenger effects in the cellular antioxidant system. This research investigated the protective effects and underlying mechanisms of melatonin action in porcine somatic cell nuclear transfer (SCNT) embryos. The results suggested that the developmental competence of porcine SCNT embryos wa...

journal_title：Scientific reports

authors： Liang S,Jin YX,Yuan B,Zhang JB,Kim NH

更新日期：2017-09-11 00:00:00

abstract：:Incompatible patterns viewed by each of the two eyes can provoke binocular rivalry, a competition of perception. Levelt's first law predicts that a highly visible stimulus will predominate over a less visible stimulus during binocular rivalry. In a behavioural study, we made a counterintuitive observation: high visibi...

journal_title：Scientific reports

authors： Skerswetat J,Formankiewicz MA,Waugh SJ

更新日期：2018-09-26 00:00:00

abstract：:Personalized medicine is a promising tool not only for prevention, screening and development of more efficient treatment strategies, but also for diminishing the side effects caused by current therapies. Deciphering gene regulation pathways provides a reliable prognostic analysis to elucidate the origin of grave disea...

journal_title：Scientific reports

authors： Huertas CS,Domínguez-Zotes S,Lechuga LM

更新日期：2017-01-25 00:00:00

abstract：:Muscle damage and loss of muscle mass are triggered by immobilization, loss of appetite, dystrophies and chronic wasting diseases. In addition, physical exercise causes muscle damage. In damaged muscle, the N-terminal and C-terminal regions of titin, a giant sarcomere protein, are cleaved by calpain-3, and the resulti...

journal_title：Scientific reports

authors： Maruyama N,Asai T,Abe C,Inada A,Kawauchi T,Miyashita K,Maeda M,Matsuo M,Nabeshima YI

更新日期：2016-12-19 00:00:00

abstract：:ZnO, aside from TiO2, has been considered as a promising material for purification and disinfection of water and air, and remediation of hazardous waste, owing to its high activity, environment-friendly feature and lower cost. However, their poor visible light utilization greatly limited their practical applications. ...

journal_title：Scientific reports

authors： Zhang X,Qin J,Xue Y,Yu P,Zhang B,Wang L,Liu R

更新日期：2014-04-04 00:00:00

abstract：:Advances in lab-on-a-chip (LOC) devices have led to significant improvements in the on-chip manipulation, separation, sorting, and isolation of particles and cells. Among various LOC-based approaches such as inertia-based methods, acoustophoresis, and magnetophoresis, the planar-slanted-electrode dielectrophoresis (DE...

journal_title：Scientific reports

authors： Dalili A,Taatizadeh E,Tahmooressi H,Tasnim N,Rellstab-Sánchez PI,Shaunessy M,Najjaran H,Hoorfar M

更新日期：2020-07-16 00:00:00

abstract：:In this study, a simple technique was developed for the electrochemical detection of anionic analytes in weakly supported media. This was conducted by the use of electrochemical paper-based analytical devices (ePADs). A sensing platform was modified with nereistoxin and used to determine nitrite as a case study. The e...

journal_title：Scientific reports

authors： Khoshroo A,Fattahi A

更新日期：2020-09-03 00:00:00

abstract：:Generally confinement size is considered to determine the dimensionality of nanostructures. While the exciton Bohr radius is used as a criterion to define either weak or strong confinement in optical experiments, the binding energy of confined excitons is difficult to measure experimentally. One alternative is to use ...

journal_title：Scientific reports

authors： Kim H,Lee W,Park S,Kyhm K,Je K,Taylor RA,Nogues G,Dang LS,Song JD

更新日期：2017-01-05 00:00:00

abstract：:Increasingly researchers are looking to bring together perspectives across multiple scales, or to combine insights from different techniques, for the same region of interest. To this end, correlative microscopy has already yielded substantial new insights in two dimensions (2D). Here we develop correlative tomography ...

journal_title：Scientific reports

authors： Burnett TL,McDonald SA,Gholinia A,Geurts R,Janus M,Slater T,Haigh SJ,Ornek C,Almuaili F,Engelberg DL,Thompson GE,Withers PJ

更新日期：2014-04-16 00:00:00