Establishment of a highly sensitive sandwich ELISA for the N-terminal fragment of titin in urine.

abstract：:We propose a hybrid plasmonic device consisting of a planar dielectric waveguide covering a gold nanostripe array fabricated on a gold film and investigate its guiding properties at telecom wavelengths. The fundamental modes of a hybrid device and their dependence on the key geometric parameters are studied. A communi...

journal_title：Scientific reports

authors： Thomas PA,Auton GH,Kundys D,Grigorenko AN,Kravets VG

更新日期：2017-03-24 00:00:00

abstract：:Owing to the growing infectious diseases caused by eukaryotic and prokaryotic pathogens, it is urgent to develop novel antimicrobial agents against clinical pathogenic infections. Biofilm formation and invasion into the host cells are vital processes during pathogenic colonization and infection. In this study, we test...

journal_title：Scientific reports

authors： Yu Q,Li J,Zhang Y,Wang Y,Liu L,Li M

更新日期：2016-05-25 00:00:00

abstract：:Periconceptional supplementation with folic acid reduces the occurrence of neural tube defects (NTDs). The association between maternal abnormalities in homocysteine metabolism (e.g., hyperhomocysteinaemia, folate deficiency and low vitamin B12) and the risk of NTDs-affected pregnancies has been widely evaluated in re...

journal_title：Scientific reports

authors： Tang KF,Li YL,Wang HY

更新日期：2015-03-02 00:00:00

abstract：:Chronic suppurative otitis media (CSOM) is one of the most common infectious diseases of the middle ear especially affecting children, leading to delay in language development and communication. Although Staphylococcus aureus is the most common pathogen associated with CSOM, its interaction with middle ear epithelial ...

journal_title：Scientific reports

authors： Mittal R,Debs LH,Patel AP,Nguyen D,Blackwelder P,Yan D,Weckwerth PH,Liu XZ

更新日期：2019-07-25 00:00:00

abstract：:Dengue is a mild flu-like arboviral illness caused by dengue virus (DENV) that occurs in tropical and subtropical countries. An increasing number of reports have been indicating that dengue is also associated to neurological manifestations, however, little is known regarding the neuropathogenesis of the disease. Here,...

journal_title：Scientific reports

authors： Salomão NG,Rabelo K,Póvoa TF,Alves AMB,da Costa SM,Gonçalves AJS,Amorim JF,Azevedo AS,Nunes PCG,Basílio-de-Oliveira CA,Basílio-de-Oliveira RP,Geraldo LHM,Fonseca CG,Lima FRS,Mohana-Borges R,Silva EM,Dos Santos FB,Olivei

更新日期：2018-06-27 00:00:00

abstract：:Network analysis is an important tool to analyze the structure of complex systems such as tropical forests. Here, we infer spatial proximity networks in tropical forests by using network science. First, we focus on tree neighborhoods to derive spatial tree networks from forest inventory data. In a second step, we cons...

journal_title：Scientific reports

authors： Schmid JS,Taubert F,Wiegand T,Sun IF,Huth A

更新日期：2020-08-06 00:00:00

abstract：:Here we report a compact multilayer film structure for angle robust color filtering, which is verified by theoretical calculations and experiment results. The introduction of the amorphous silicon in the proposed unsymmetrical resonant cavity greatly reduces the angular sensitivity of the filters, which is confirmed b...

journal_title：Scientific reports

authors： Yang C,Shen W,Zhang Y,Li K,Fang X,Zhang X,Liu X

更新日期：2015-03-19 00:00:00

abstract：:The involvement of the immune system, particularly the role of T-cells, in sarcoidosis is unclear. The existence of higher CD4+ T-cells and increased CD4/CD8 ratio may indicate a pathogenic role of T-cells in the disease. In this study, we quantified the contribution of T-cells associated variants and of CD4/CD8 ratio...

journal_title：Scientific reports

authors： Rivera NV,Hagemann-Jensen M,Ferreira MAR,Kullberg S,Eklund A,Martin NG,Padyukov L,Grunewald J

更新日期：2017-07-17 00:00:00

abstract：:Marigold (Tagetes erecta L.) is an important ornamental plant with a wide variety of flower colors. Despite its economic value, few biochemical and molecular studies have explored the generation of flower color in this species. To study the mechanism underlying marigold petal color, we performed a metabolite analysis ...

journal_title：Scientific reports

authors： Zhang H,Zhang S,Zhang H,Chen X,Liang F,Qin H,Zhang Y,Cong R,Xin H,Zhang Z

更新日期：2020-10-08 00:00:00

abstract：:Aurantiochytrium is a promising docosahexaenoic acid (DHA) production candidate due to its fast growth rate and high proportions of lipid and DHA content. In this study, high-throughput RNA sequencing technology was employed to explore the acclimatization of this DHA producer under cold stress at the transcriptional l...

journal_title：Scientific reports

authors： Ma Z,Tan Y,Cui G,Feng Y,Cui Q,Song X

更新日期：2015-09-25 00:00:00

abstract：:Leukocyte-platelet rich fibrin (L-PRF) is extensively used in the dentistry field and other clinical scenarios due to its regeneration properties. The goal of the present study was to depict the L-PRF secretome and how it changes over time. We obtained L-PRF membranes and cultured them in DMEM. The secretome was colle...

journal_title：Scientific reports

authors： Hermida-Nogueira L,Barrachina MN,Morán LA,Bravo S,Diz P,García Á,Blanco J

更新日期：2020-09-03 00:00:00

abstract：:We report low-temperature solution-processed p-CuO nanorods (NRs)/n-ZnO NRs heterojunction light emitting diode (LED), exploiting the native point defects of ZnO NRs. ZnO NRs were synthesized at 90 °C by using hydrothermal method while CuO NRs were synthesized at 100 °C by using microwave reaction system. The electric...

journal_title：Scientific reports

authors： Biswas P,Baek SD,Lee SH,Park JH,Lee SJ,Lee TI,Myoung JM

更新日期：2015-12-09 00:00:00

abstract：:The interaction between roots and bacterial communities in halophytic species is poorly understood. Here, we used Jerusalem artichoke cultivar Nanyu 1 (NY-1) to characterise root distribution patterns and determine diversity and abundance of bacteria in the rhizosphere soil under variable salinity. Root growth was not...

journal_title：Scientific reports

authors： Yang H,Hu J,Long X,Liu Z,Rengel Z

更新日期：2016-02-08 00:00:00

abstract：:The nonsynonymous SCN10A single nucleotide polymorphism (SNP) rs6795970 has been reported to associate with PR interval and atrial fibrillation (AF) and in strong linkage disequilibrium (LD) with the AF-associated SNP rs6800541. In this study, we investigated whether rs6795970 polymorphisms are associated with AF recu...

journal_title：Scientific reports

authors： Wu H,Xu J,Chen S,Zhou G,Qi B,Wei Y,Hu E,Tang D,Chen G,Li H,Zhao L,Shi Y,Liu S

更新日期：2017-03-10 00:00:00

abstract：:With the continuous urbanization and industrialization in the world, energy saving and greenhouse gas (GHG) emission reduction have been serious issues to be addressed, for which heat recovery from traditional energy-intensive industries makes up a significant strategy. Here we report a novel approach to extract the w...

journal_title：Scientific reports

authors： Sun Y,Sridhar S,Liu L,Wang X,Zhang Z

更新日期：2015-11-12 00:00:00

abstract：:Electrospinning can be used to mimic the architecture of an acellular nerve graft, combining microfibers for guidance, and pores for cellular infiltration. We made electrospun nerve guides, from polycaprolactone (PCL) or poly-L-lactic acid (PLLA), with aligned fibers along the insides of the channels and random fibers...

journal_title：Scientific reports

authors： Frost HK,Andersson T,Johansson S,Englund-Johansson U,Ekström P,Dahlin LB,Johansson F

更新日期：2018-11-13 00:00:00

abstract：:Lysophospholipids (LPLs) are known to have potentially important roles in the initiation and maintenance of neuropathic pain in animal models. This study investigated the association between the clinical severity of lumbar spinal stenosis (LSS) and the cerebrospinal fluid (CSF) levels of LPLs, using human samples. We ...

journal_title：Scientific reports

authors： Hayakawa K,Kurano M,Ohya J,Oichi T,Kano K,Nishikawa M,Uranbileg B,Kuwajima K,Sumitani M,Tanaka S,Aoki J,Yatomi Y,Chikuda H

更新日期：2019-06-24 00:00:00

abstract：:Among the multiple metabolic signals involved in the establishment of the hepatic zonation, oxygen could play a key role. Indeed, depending on hepatocyte position in the hepatic lobule, gene expression and metabolism are differently affected by the oxygen gradient present across the lobule. The aim of this study is to...

journal_title：Scientific reports

authors： Tonon F,Giobbe GG,Zambon A,Luni C,Gagliano O,Floreani A,Grassi G,Elvassore N

更新日期：2019-09-19 00:00:00

abstract：:Organic nanofibers have found various applications in optoelectronic devices. In such devices, exciton diffusion is a major aspect concerning their efficiency. In the case of singlet excitons, Förster transfer is the mechanism responsible for this process. Temperature and morphology are factors known to influence exci...

journal_title：Scientific reports

authors： de Sousa LE,da Silva Filho DA,de Sousa RT Jr,de Oliveira Neto PH

更新日期：2018-09-19 00:00:00

abstract：:Multiple applications of genome editing by CRISPR-Cas9 necessitate stringent regulation and Cas9 variants have accordingly been generated whose activity responds to small ligands, temperature or light. However, these approaches are often impracticable, for example in clinical therapeutic genome editing in situ or gene...

journal_title：Scientific reports

authors： Suzuki T,Asami M,Patel SG,Luk LYP,Tsai YH,Perry ACF

更新日期：2018-07-03 00:00:00

abstract：:The artificial earthquake of mb 6.1 related to the North Korea's sixth nuclear test occured at Mt. Mantap, North Korea on September 3, 2017. It was reported that a large and complex surface deformation was caused by the event. The surface deformation was composed of expansion of explosions, collapse, compaction and la...

journal_title：Scientific reports

authors： Baek WK,Jung HS,Kim TS

更新日期：2020-10-20 00:00:00

abstract：:While chromatin modifications can offer a useful readout for enhancer activities, it is less clear whether these modification marks are a cause or consequence of transcription factor occupancy and enhancer activation. We have examined in details the temporal events of acetyltransferase associations and histone acetyla...

journal_title：Scientific reports

authors： Hamed M,Khilji S,Chen J,Li Q

更新日期：2013-01-01 00:00:00

abstract：:Melatonin has antioxidant and scavenger effects in the cellular antioxidant system. This research investigated the protective effects and underlying mechanisms of melatonin action in porcine somatic cell nuclear transfer (SCNT) embryos. The results suggested that the developmental competence of porcine SCNT embryos wa...

journal_title：Scientific reports

authors： Liang S,Jin YX,Yuan B,Zhang JB,Kim NH

更新日期：2017-09-11 00:00:00

abstract：:Cystine-knot peptides are attractive templates in drug discovery due to a number of features they possess including their 3D conformation, physicochemical stability and synthetic tractability. Yet, their cellular uptake mechanisms remain largely unexplored. Recently, we demonstrated that the cystine-knot peptide EETI-...

journal_title：Scientific reports

authors： Gao X,De Mazière A,Iaea DB,Arthur CP,Klumperman J,Ciferri C,Hannoush RN

更新日期：2019-05-06 00:00:00

abstract：:Polypyrrole complex nitrogen-doped porous carbon matrix (PPy/N-PCM) was synthesized by a simple two-step method. Firstly, graphene oxide was prepared by the modified Hummers method. Secondly, Polypyrrole was compounded on the graphene oxide substrate, and the carbon matrix with a high specific surface area was obtaine...

journal_title：Scientific reports

authors： Feng M,Lu W,Zhou Y,Zhen R,He H,Wang Y,Li C

更新日期：2020-09-21 00:00:00

abstract：:Photodynamic therapy (PDT) is a technique developed to treat the ever-increasing global incidence of cancer. This technique utilises singlet oxygen ((1)O2) generation via a laser excited photosensitiser (PS) to kill cancer cells. However, prolonged sensitivity to intensive light (6-8 weeks for lung cancer), relatively...

journal_title：Scientific reports

authors： Sokolovski SG,Zolotovskaya SA,Goltsov A,Pourreyron C,South AP,Rafailov EU

更新日期：2013-12-12 00:00:00

abstract：:Tuberculosis is the leading cause of death among people living with HIV (PLH). Preventive tuberculosis therapy reduces mortality in PLH, especially in those with a positive tuberculin skin test (TST). New, more specific technologies for detecting latent tuberculosis infection (LTBI) are now commercially available. We ...

journal_title：Scientific reports

authors： Steffen RE,Pinto M,Kritski A,Trajman A

更新日期：2020-12-11 00:00:00

abstract：:Doxorubicin (Dox) is a highly effective anticancer drug but cause acute ventricular dysfunction, and also induce late-onset cardiomyopathy and heart failure. Despite extensive studies, the pathogenic sequelae leading to the progression of Dox-associated cardiomyopathy remains unknown. We assessed temporal changes in a...

journal_title：Scientific reports

authors： Abdullah CS,Alam S,Aishwarya R,Miriyala S,Bhuiyan MAN,Panchatcharam M,Pattillo CB,Orr AW,Sadoshima J,Hill JA,Bhuiyan MS

更新日期：2019-02-14 00:00:00

abstract：:Climate change significantly affects geographic distribution of plants pests and diseases worldwide. Understanding the influence of future climate change on the suitable areas of Diaphorina citri (Kuwayama) in our country and taking timely countermeasures are crucial for improving the effectiveness of control of pest....

journal_title：Scientific reports

authors： Wang R,Yang H,Wang M,Zhang Z,Huang T,Wen G,Li Q

更新日期：2020-06-08 00:00:00

abstract：:The impact of statin therapy on plasma asymmetric dimethylarginine (ADMA) levels has not been conclusively studied. Therefore the aim of the meta-analysis was to assess the effect of statins on circulating ADMA levels. We searched selected databases (up to August 2014) to identify randomized controlled trials (RCTs) t...

journal_title：Scientific reports

authors： Serban C,Sahebkar A,Ursoniu S,Mikhailidis DP,Rizzo M,Lip GY,Kees Hovingh G,Kastelein JJ,Kalinowski L,Rysz J,Banach M

更新日期：2015-05-13 00:00:00