Doxorubicin-induced cardiomyopathy associated with inhibition of autophagic degradation process and defects in mitochondrial respiration.

abstract：:Nearly half of the world's population obtains its daily calories from rice grains, which lack or have insufficient levels of essential micronutrients. The deficiency of micronutrients vital for normal growth is a global health problem, and iron, zinc and vitamin A deficiencies are the most prevalent ones. We developed...

journal_title：Scientific reports

authors： Singh SP,Gruissem W,Bhullar NK

更新日期：2017-07-31 00:00:00

abstract：:Materials' mechanical properties highly depend on their internal structures. Designing novel structure is an effective route to improve materials' performance. One-dimensional disordered (ODD) structure is a kind of particular structure in silicon carbide (SiC), which highly affects its mechanical properties. Herein, ...

journal_title：Scientific reports

authors： Zhang X,Wang J,Yang Z,Tang X,Yue Y

更新日期：2020-07-09 00:00:00

abstract：:Interferometry-based online partial discharge (PD) monitor presented in this paper can detect the occurrence of PD sensitively, evaluate the peak value of the discharge inception voltage with random waveform and the damage extent relatively cost effectively. The interferograms affected by the PD are collected online. ...

journal_title：Scientific reports

authors： Xue L,Zhu Y,Yang C,Kumarawadu S

更新日期：2020-11-04 00:00:00

abstract：:Two-dimensional (2D) acoustic vortex allows new physics and applications different from three-dimensional counterparts, yet existing mechanisms usually have to rely on active array composed of transducers which may result in complexity, high cost and, in particular, undesired spatial aliasing effect. We propose to gen...

journal_title：Scientific reports

authors： Liu JJ,Liang B,Yang J,Yang J,Cheng JC

更新日期：2020-03-02 00:00:00

abstract：:Soybean seeds are an important source of vegetable oil and biomaterials. The content of individual triacylglycerol species (TAG) in soybean seeds is difficult to quantify in an accurate and rapid way. The present study establishes an approach to quantify TAG species in soybean seeds utilizing an electrospray ionizatio...

journal_title：Scientific reports

authors： Li M,Butka E,Wang X

更新日期：2014-10-10 00:00:00

abstract：:Skeletal muscle and adipose tissue play an important role in maintaining metabolic homeostasis and thermogenesis. We aimed to investigate the effects of single and repeated exposure to whole-body cryotherapy in volunteers with different physical fitness levels on 25-hydroxyvitamin D (25(OH)D) and myokines. The study i...

journal_title：Scientific reports

authors： Śliwicka E,Cisoń T,Straburzyńska-Lupa A,Pilaczyńska-Szcześniak Ł

更新日期：2020-04-10 00:00:00

abstract：:Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies. The analysis was performed using data from the Ansung-Ansan cohort study. We categorized the participants into ...

journal_title：Scientific reports

authors： Lee DY,Yoo MG,Kim HJ,Jang HB,Kim JH,Lee HJ,Park SI

更新日期：2017-08-04 00:00:00

abstract：:Recently, we reported that chemokine (C-X-C motif) receptor (CXCR)4 and atypical chemokine receptor 3 regulate α1-adrenergic receptors (α1-AR) through the formation of hetero-oligomeric complexes. Whether α1-ARs also regulate chemokine receptor function within such heteromeric receptor complexes is unknown. We observe...

journal_title：Scientific reports

authors： Gao X,Albee LJ,Volkman BF,Gaponenko V,Majetschak M

更新日期：2018-02-09 00:00:00

abstract：:Past evidence of an early Processing Negativity in auditory Go/NoGo event-related potential (ERP) data suggests that young adults proactively process sensory information in two-choice tasks. This study aimed to clarify the occurrence of Go/NoGo Processing Negativity and investigate the ERP component series related to ...

journal_title：Scientific reports

authors： Fogarty JS,Barry RJ,Steiner GZ

更新日期：2020-03-04 00:00:00

abstract：:Basal-like breast cancer (BLBC) is associated with a poor clinical outcome due to the few treatment options and absence of effective targeted agents. Here, we show that malic enzyme 1 (ME1) is dramatically upregulated in BLBC due to ME1 copy number amplification. ME1 expression increases glucose uptake and lactate pro...

journal_title：Scientific reports

authors： Liao R,Ren G,Liu H,Chen X,Cao Q,Wu X,Li J,Dong C

更新日期：2018-11-13 00:00:00

abstract：:Flotation of small solid objects and liquid droplets on water is critical to natural and industrial activities. This paper reports the floating mechanism of liquid marbles, or liquid droplets coated with hydrophobic microparticles. We used X-ray computed tomography (XCT) to acquire cross-sectional images of the floati...

journal_title：Scientific reports

authors： Ooi CH,Plackowski C,Nguyen AV,Vadivelu RK,St John JA,Dao DV,Nguyen NT

更新日期：2016-02-23 00:00:00

abstract：:Electrospun polycaprolactone (PCL) vascular grafts showed good mechanical properties and patency. However, the slow degradation of PCL limited vascular regeneration in the graft. Polydioxanone (PDS) is a biodegradable polymer with high mechanical strength and moderate degradation rate in vivo. In this study, a small-d...

journal_title：Scientific reports

authors： Pan Y,Zhou X,Wei Y,Zhang Q,Wang T,Zhu M,Li W,Huang R,Liu R,Chen J,Fan G,Wang K,Kong D,Zhao Q

更新日期：2017-06-15 00:00:00

abstract：:The regeneration capacity of knee cartilage can be enhanced by applying periosteal grafts, but this effect varies depending on the different sources of the periosteal grafts applied for cartilage formation. Tibia periosteum can be used to enhance cartilage repair. However, long-term analysis has not been conducted. Th...

journal_title：Scientific reports

authors： Hsiao HY,Cheng CM,Kao SW,Liu JW,Chang CS,Harhaus L,Huang JJ

更新日期：2020-05-20 00:00:00

abstract：:This report identifies mitochondrial DNA (mtDNA) as a target and active mediator that links low-level oxidative stress to inflammatory response in pulmonary epithelial cells. Extrusion of mtDNA into the bronchoalveolar lavage fluid occurs as an early event in mice subjected to cigarette smoke injury, concomitantly wit...

journal_title：Scientific reports

authors： Szczesny B,Marcatti M,Ahmad A,Montalbano M,Brunyánszki A,Bibli SI,Papapetropoulos A,Szabo C

更新日期：2018-01-17 00:00:00

abstract：:Users of social media often share their feelings or emotional states through their posts. In this study, we developed a deep learning model to identify a user's mental state based on his/her posting information. To this end, we collected posts from mental health communities in Reddit. By analyzing and learning posting...

journal_title：Scientific reports

authors： Kim J,Lee J,Park E,Han J

更新日期：2020-07-16 00:00:00

abstract：:CoO nanocrystal/graphene nanosheets (GNS) composites, consisting of a triangular CoO nanocrystal of 2~20 nm on the surface of GNS, are synthesized by a mild synthetic method. First, cobalt acetate tetrahydrate is recrystallized in the alcohol solution at a low temperature. Then, graphene oxide mixed with cobalt-precur...

journal_title：Scientific reports

authors： Guan Q,Cheng J,Li X,Wang B,Huang L,Nie F,Ni W

更新日期：2015-05-11 00:00:00

abstract：:Copper zinc tin sulfide (CZTS) is a promising material for harvesting solar energy due to its abundance and non-toxicity. However, its poor performance hinders their wide application. In this paper gold (Au) nanoparticles are successfully incorporated into CZTS to form Au@CZTS core-shell nanostructures. The photocatho...

journal_title：Scientific reports

authors： Zhang X,Wu X,Centeno A,Ryan MP,Alford NM,Riley DJ,Xie F

更新日期：2016-03-21 00:00:00

abstract：:Nisin inhibits bacterial growth by generating pores in cell membrane and interrupting cell-wall biosynthesis through specific lipid II interaction. However, the role of the hinge region and C-terminus residues of the peptide in antibacterial action of nisin is largely unknown. Here, using molecular dynamics simulation...

journal_title：Scientific reports

authors： Prince A,Sandhu P,Ror P,Dash E,Sharma S,Arakha M,Jha S,Akhter Y,Saleem M

更新日期：2016-11-29 00:00:00

abstract：:Although the growth of graphene by chemical vapor deposition is a production technique that guarantees high crystallinity and superior electronic properties on large areas, it is still a challenge for manufacturers to efficiently scale up the production to the industrial scale. In this context, issues related to the p...

journal_title：Scientific reports

authors： Lisi N,Dikonimos T,Buonocore F,Pittori M,Mazzaro R,Rizzoli R,Marras S,Capasso A

更新日期：2017-08-30 00:00:00

abstract：:A negative correlation between body size and the latitudinal temperature gradient is well established for extant terrestrial endotherms but less so in the fossil record. Here we analyze the middle Eocene site of Geiseltal (Germany), whose record is considered to span ca. 5 Myrs of gradual global cooling, and generate ...

journal_title：Scientific reports

authors： Ring SJ,Bocherens H,Wings O,Rabi M

更新日期：2020-03-04 00:00:00

abstract：:Influenza virus neuraminidase (NA) is the primary target for influenza therapeutics. Severe complications are often related to secondary pneumonia caused by Streptococcus pneumoniae (pneumococci), which also express NAs. Recently, a NA-mediated lethal synergism between influenza A viruses and pneumococci was described...

journal_title：Scientific reports

authors： Grienke U,Richter M,Walther E,Hoffmann A,Kirchmair J,Makarov V,Nietzsche S,Schmidtke M,Rollinger JM

更新日期：2016-06-03 00:00:00

abstract：:The Southern Ocean has taken up more than 40% of the total anthropogenic carbon (Cant) stored in the oceans since the preindustrial era, mainly in subantarctic mode and intermediate waters (SAMW-AAIW). However, the physical mechanisms responsible for the transfer of Cant into the ocean interior remain poorly understoo...

journal_title：Scientific reports

authors： Langlais CE,Lenton A,Matear R,Monselesan D,Legresy B,Cougnon E,Rintoul S

更新日期：2017-12-06 00:00:00

abstract：:The indirect interactions between insect vectors, such as whiteflies, and the viruses they transmit, such as begomoviruses, via host plants may produce a range of outcome depending on the species/strain of each of the three organisms involved, and the mechanisms underlying the variations are not well understood. Here,...

journal_title：Scientific reports

authors： Sun YC,Pan LL,Ying FZ,Li P,Wang XW,Liu SS

更新日期：2017-04-03 00:00:00

abstract：:Antimicrobial peptides (AMPs) are an important part of the human innate immune system for protection against bacterial infections, however the AMPs display varying degrees of activity against Staphylococcus aureus. Previously, we showed that inactivation of the ATP synthase sensitizes S. aureus towards the AMP antibio...

journal_title：Scientific reports

authors： Liu L,Beck C,Nøhr-Meldgaard K,Peschel A,Kretschmer D,Ingmer H,Vestergaard M

更新日期：2020-07-09 00:00:00

abstract：:Despite the efficacy of synthetic fungicides in controlling postharvest diseases, public concerns regarding chemical residues in food and an increase in drug-resistant strains of pathogens have led to a need for new agents to control postharvest diseases. The current study was performed to find control agents of micro...

journal_title：Scientific reports

authors： Kim JD,Park MY,Jeon BJ,Kim BS

更新日期：2019-09-19 00:00:00

abstract：:The largest tsunamis are generated by seafloor uplift resulting from rupture of offshore subduction-zone megathrusts. The rupture of the shallowest part of a megathrust often produces unexpected outsize tsunami relative to their seismic magnitude. These are so called 'tsunami earthquakes', which are difficult to ident...

journal_title：Scientific reports

authors： Manta F,Occhipinti G,Feng L,Hill EM

更新日期：2020-07-06 00:00:00

abstract：:Leaf flattening influences plant photosynthesis, thereby affecting product yield and quality. Here, we obtained a stably inherited leaf crinkled mutant (lcm), derived from the Chinese cabbage doubled haploid (DH) 'FT' line using EMS mutagenesis combined with isolated microspore culture. The crinkled phenotype was cont...

journal_title：Scientific reports

authors： Zhang M,Huang S,Gao Y,Fu W,Qu G,Zhao Y,Shi F,Liu Z,Feng H

更新日期：2020-08-18 00:00:00

abstract：:The synthesis of artificial cell is a route for searching the origin of protocell. Here, we create a novel cell model of graphene capsules with selective ion channels, indicating that graphene might be an embryo of protocell membrane. Firstly, we found that the highly oxidized graphene and phospholipid-graphene oxide ...

journal_title：Scientific reports

authors： Li Z,Wang C,Tian L,Bai J,Yao H,Zhao Y,Zhang X,Cao S,Qi W,Wang S,Shi K,Xu Y,Mingliang Z,Liu B,Qiu H,Liu J,Wu W,Wang X,Wenzhen A

更新日期：2015-05-19 00:00:00

abstract：:Ctenodactylinae (gundis) is a clade of rodents that experienced, in Miocene time, their greatest diversification and widest distribution. They expanded from the Far East, their area of origin, to Africa, which they entered from what would become the Arabian Peninsula. Questions concerning the origin of African Ctenoda...

journal_title：Scientific reports

authors： López-Antoñanzas R,Knoll F,Maksoud S,Azar D

更新日期：2015-08-07 00:00:00

abstract：:We describe a multiplexed RNA aptamer selection to 19 different targets simultaneously using a microcolumn-based device, MEDUSA (Microplate-based Enrichment Device Used for the Selection of Aptamers), as well as a modified selection process, that significantly reduce the time and reagents needed for selections. We exp...

journal_title：Scientific reports

authors： Reinholt SJ,Ozer A,Lis JT,Craighead HG

更新日期：2016-07-19 00:00:00