Cost-effectiveness of newer technologies for the diagnosis of Mycobacterium tuberculosis infection in Brazilian people living with HIV.

abstract：:The modern Asian monsoonal systems are currently believed to have originated around the end of the Oligocene following a crucial step of uplift of the Tibetan-Himalayan highlands. Although monsoon possibly drove the evolution of many mammal lineages during the Neogene, no evidence thereof has been provided so far. We ...

journal_title：Scientific reports

authors： López-Antoñanzas R,Knoll F,Wan S,Flynn LJ

更新日期：2015-03-11 00:00:00

abstract：:Cell surface expression of alpha-enolase, a glycolytic enzyme displaying moonlighting activities, has been shown to contribute to the motility and invasiveness of cancer cells through the protein non-enzymatic function of binding plasminogen and enhancing plasmin formation. Although a few recent records indicate the i...

journal_title：Scientific reports

authors： Perconti G,Maranto C,Romancino DP,Rubino P,Feo S,Bongiovanni A,Giallongo A

更新日期：2017-06-19 00:00:00

abstract：:Fluorescent proteins (FP) are used to study various biological processes. Recently, a series of near-infrared (NIR) FPs based on bacterial phytochromes was developed. Finding ways to improve NIR FPs is becoming progressively important. By applying rational design and molecular evolution we have engineered R. palustris...

journal_title：Scientific reports

authors： Rumyantsev KA,Shcherbakova DM,Zakharova NI,Emelyanov AV,Turoverov KK,Verkhusha VV

更新日期：2015-12-18 00:00:00

abstract：:Osthole, an active coumarin isolated from Cnidium monnieri (L.) Cusson, has long been used in China as an antipruritic herbal medicine; however, the antipruitic mechanism of osthole is unknown. We studied the molecular mechanism of osthole in histamine-dependent itch by behavioral test, Ca(2+) imaging, and electrophys...

journal_title：Scientific reports

authors： Yang NN,Shi H,Yu G,Wang CM,Zhu C,Yang Y,Yuan XL,Tang M,Wang ZL,Gegen T,He Q,Tang K,Lan L,Wu GY,Tang ZX

更新日期：2016-05-10 00:00:00

abstract：:Hepatocellular carcinoma is a common type of malignancy with a poor prognosis. Identification and utilisation of markers for monitoring and diagnosis are urgently needed. Alpha-fetoprotein (AFP) and Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II) have been proved to be efficient biomarkers for hepatit...

journal_title：Scientific reports

authors： Wang G,Lu X,Du Q,Zhang G,Wang D,Wang Q,Guo X

更新日期：2020-08-11 00:00:00

abstract：:Damage of enteric neurons and partial or total loss of selective neuronal populations are reported in intestinal disorders including inflammatory bowel diseases and necrotizing enterocolitis. To develop three-dimensional scaffolds for enteric neurons we propose the decoration of ionic-complementary self-assembling pep...

journal_title：Scientific reports

authors： Brun P,Zamuner A,Peretti A,Conti J,Messina GML,Marletta G,Dettin M

更新日期：2019-04-03 00:00:00

abstract：:Generally, plant roots shape the rhizosphere fungal community but how individual plant genes involved in senescence affect this shaping is less studied. We used an early senescence leaf (esl) mutant rice and compared it with its isogenic wild type variety to evaluate the effect of the vacuolar H+-ATPase (VHA-A1) gene ...

journal_title：Scientific reports

authors： Letuma P,Arafat Y,Waqas M,Lin F,Lin W,Zhang Y,Masita M,Fan K,Li Z,Lin W

更新日期：2018-11-30 00:00:00

abstract：:The ecological consequences of habitat loss and fragmentation have been intensively studied on a broad, landscape-wide scale, but have less been investigated on the finer scale of individual habitat patches, especially when considering dynamic turnovers in the habitability of sites. We study changes to individual patc...

journal_title：Scientific reports

authors： Kun Á,Oborny B,Dieckmann U

更新日期：2019-07-31 00:00:00

abstract：:Metal-organic frameworks (MOFs) formed from metals and organic ligands, are crystalline materials that are degradable in aqueous medium, and capable of releasing Ca and Sr ions. In this manuscript, the ability of MOFs to degrade and release osteogenic Ca and Sr ions was investigated. MOFs were generated by choosing os...

journal_title：Scientific reports

authors： Joseph N,Lawson HD,Overholt KJ,Damodaran K,Gottardi R,Acharya AP,Little SR

更新日期：2019-09-10 00:00:00

abstract：:Centrosomal protein 55 (CEP55) is a microtubule-bundling protein that participants in cell mitosis. It is overexpressed in several solid tumours and promotes the growth and invasion of cancer cells. However, the role of CEP55 in pancreatic cancer (PANC) remains unclear. Herein, upregulated expression of CEP55 (associa...

journal_title：Scientific reports

authors： Peng T,Zhou W,Guo F,Wu HS,Wang CY,Wang L,Yang ZY

更新日期：2017-07-19 00:00:00

abstract：:Here, we describe a new strategy that allows the rapid and efficient engineering of mono and multispecific trivalent antibodies. By fusing single-domain antibodies from camelid heavy-chain-only immunoglobulins (VHHs) to the N-terminus of a human collagen XVIII trimerization domain (TIE(XVIII)) we produced monospecific...

journal_title：Scientific reports

authors： Alvarez-Cienfuegos A,Nuñez-Prado N,Compte M,Cuesta AM,Blanco-Toribio A,Harwood SL,Villate M,Merino N,Bonet J,Navarro R,Muñoz-Briones C,Sørensen KM,Mølgaard K,Oliva B,Sanz L,Blanco FJ,Alvarez-Vallina L

更新日期：2016-06-27 00:00:00

abstract：:Pharmacological activities of some natural products diminish and even disappear after purification. In this study, we explored the mechanisms underlying the decrease of acute oral toxicity of Coptidis Rhizoma extract after purification. The water solubility, in vitro absorption, and plasma exposure of berberine (the m...

journal_title：Scientific reports

authors： Ma BL,Yin C,Zhang BK,Dai Y,Jia YQ,Yang Y,Li Q,Shi R,Wang TM,Wu JS,Li YY,Lin G,Ma YM

更新日期：2016-01-29 00:00:00

abstract：:Because of the unique selection rule, hyper-Raman scattering (HRS) can provide spectral information that linear Raman and infrared spectroscopy cannot obtain. However, the weak signal is the key bottleneck that restricts the application of HRS technique in study of the molecular structure, surface or interface behavio...

journal_title：Scientific reports

authors： Zhu S,Fan C,Ding P,Liang E,Hou H,Wu Y

更新日期：2018-08-08 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Farmery JHR,Smith ML,NIHR BioResource - Rare Diseases.,Lynch AG

更新日期：2018-09-03 00:00:00

abstract：:Vertically aligned radial-junction solar cell designs offer potential improvements over planar geometries, as carrier generation occurs close to the junction for all absorption depths, but most production methods still require a single crystal substrate. Here, we report on the fabrication of such solar cells from poly...

journal_title：Scientific reports

authors： Martinsen FA,Smeltzer BK,Nord M,Hawkins T,Ballato J,Gibson UJ

更新日期：2014-09-04 00:00:00

abstract：:Roots have important roles for plants to withstand adverse environmental conditions, including salt stress. Biostimulant application was shown to enhance plant resilience towards abiotic stresses. Here, we studied the effect of a tannin-based biostimulant on tomato (Solanum lycopersicum L.) grown under salt stress con...

journal_title：Scientific reports

authors： Campobenedetto C,Mannino G,Beekwilder J,Contartese V,Karlova R,Bertea CM

更新日期：2021-01-11 00:00:00

abstract：:We aimed to systematically investigate the potential association of matrix metalloproteinase (MMP)-9, -3, -2, and -8 gene polymorphisms with susceptibility to periodontitis using meta-analysis. A literature search in PubMed, Embase, and Web of Science was conducted to obtain relevant publications. Finally a total of 1...

journal_title：Scientific reports

authors： Weng H,Yan Y,Jin YH,Meng XY,Mo YY,Zeng XT

更新日期：2016-04-20 00:00:00

abstract：:Periconceptional supplementation with folic acid reduces the occurrence of neural tube defects (NTDs). The association between maternal abnormalities in homocysteine metabolism (e.g., hyperhomocysteinaemia, folate deficiency and low vitamin B12) and the risk of NTDs-affected pregnancies has been widely evaluated in re...

journal_title：Scientific reports

authors： Tang KF,Li YL,Wang HY

更新日期：2015-03-02 00:00:00

abstract：:In solid state science, multifunctional materials and especially multiferroics have attracted a great deal of attention, as they open the possibility for next generation spintronic and data storage devices. Interestingly, while many of them host coexisting 3d and 4f elements, the role of the coupling between these two...

journal_title：Scientific reports

authors： Chattopadhyay S,Petit S,Ressouche E,Raymond S,Balédent V,Yahia G,Peng W,Robert J,Lepetit MB,Greenblatt M,Foury-Leylekian P

更新日期：2017-11-06 00:00:00

abstract：:One procedure widely used to detect the velocity of a moving object is by using the Doppler effect. This is the perceived change in frequency of a wave caused by the relative motion between the emitter and the detector, or between the detector and a reflecting target. The relative movement, in turn, generates a time-v...

journal_title：Scientific reports

authors： Rosales-Guzmán C,Hermosa N,Belmonte A,Torres JP

更新日期：2013-10-02 00:00:00

abstract：:Which factors are related to false negative results of the interferon-γ release assay (IGRA) is unclear. This systematic review described the risk factors associated with false negative IGRA results. Two authors independently identified studies designed to evaluate risk factors for false negative IGRA results from Pub...

journal_title：Scientific reports

authors： Yamasue M,Komiya K,Usagawa Y,Umeki K,Nureki SI,Ando M,Hiramatsu K,Nagai H,Kadota JI

更新日期：2020-01-31 00:00:00

abstract：:Low-noise millimetre-wave signals are valuable for digital sampling systems, arbitrary waveform generation for ultra-wideband communications, and coherent radar systems. However, the phase noise of widely used conventional signal generators (SGs) will increase as the millimetre-wave frequency increases. Our goal has b...

journal_title：Scientific reports

authors： Ishizawa A,Nishikawa T,Goto T,Hitachi K,Sogawa T,Gotoh H

更新日期：2016-05-17 00:00:00

abstract：:In neuroblastoma (NB), one of the most common paediatric solid tumours, activation of anaplastic lymphoma kinase (ALK) is often associated with poor outcomes. Although genetic studies have identified copy number alteration and nonsynonymous mutations of ALK, the regulatory mechanism of ALK signalling at protein levels...

journal_title：Scientific reports

authors： Satoh S,Takatori A,Ogura A,Kohashi K,Souzaki R,Kinoshita Y,Taguchi T,Hossain MS,Ohira M,Nakamura Y,Nakagawara A

更新日期：2016-09-08 00:00:00

abstract：:Bleaching, the loss of algal symbionts, occurs in marine photosymbiotic organisms at water temperatures minimally exceeding average summer SST (sea surface temperatures). Pre-adaptation allows organisms to persist under warmer conditions, providing the tolerance can be carried to new habitats. Here we provide evidence...

journal_title：Scientific reports

authors： Schmidt C,Titelboim D,Brandt J,Herut B,Abramovich S,Almogi-Labin A,Kucera M

更新日期：2016-08-09 00:00:00

abstract：:Glutamine metabolism and the mechanistic target of rapamycin (mTOR) pathway are activated cooperatively in the differentiation and activation of inflammatory immune cells. But the combined inhibition of both pathways was rarely investigated. This study investigated how inhibiting both glutamine metabolism with 6-diazo...

journal_title：Scientific reports

authors： Ueda Y,Saegusa J,Okano T,Sendo S,Yamada H,Nishimura K,Morinobu A

更新日期：2019-04-23 00:00:00

abstract：:Echovirus 11 (E-11) is one of the most frequently isolated enteroviruses causing meningitis and other diseases such as hand, foot, and mouth disease (HFMD) and acute flaccid paralysis (AFP). Fifty-nine newly determined E-11 VP1 sequences from the China AFP and HFMD surveillance network and 500 E-11 VP1 sequences obtai...

journal_title：Scientific reports

authors： Li J,Yan D,Chen L,Zhang Y,Song Y,Zhu S,Ji T,Zhou W,Gan F,Wang X,Hong M,Guan L,Shi Y,Wu G,Xu W

更新日期：2019-07-22 00:00:00

abstract：:We assessed the relationship between the heterogeneity of HCC on preoperative non-contrast-enhanced CT and patient prognosis. The heterogeneity of CT images from 122 patients was assessed and texture feature parameters such as mean, standard deviation (SD), entropy, mean of the positive pixels (MPP), skewness, and kur...

journal_title：Scientific reports

authors： Kiryu S,Akai H,Nojima M,Hasegawa K,Shinkawa H,Kokudo N,Yasaka K,Ohtomo K

更新日期：2017-10-04 00:00:00

abstract：:The purpose of this work is to make a case for epidemiological models with fractional exponent in the contribution of sub-populations to the incidence rate. More specifically, we question the standard assumption in the literature on epidemiological models, where the incidence rate dictating propagation of infections i...

journal_title：Scientific reports

authors： Taghvaei A,Georgiou TT,Norton L,Tannenbaum A

更新日期：2020-11-30 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening acute inflammatory vesiculobullous reactions of the skin and mucous membranes. These severe cutaneous drug reactions are known to be caused by inciting drugs and infectious agents. Previously, we have reported the association of H...

journal_title：Scientific reports

authors： Nakatani K,Ueta M,Khor SS,Hitomi Y,Okudaira Y,Masuya A,Wada Y,Sotozono C,Kinoshita S,Inoko H,Tokunaga K

更新日期：2019-11-07 00:00:00

abstract：:Siwei Jianghuang Decoction Powder (SWJH) documented originally in the Four Medical Tantras-Blue Glaze exhibited beneficial effects on diabetic nephropathy (DN) via combined synergistically action of multiple formula components including Curcumae longae Rhizoma, Berberidis dictyophyllae Cortex, Phyllanthi Fructus and T...

journal_title：Scientific reports

authors： Lai X,Tong D,Ai X,Wu J,Luo Y,Zuo F,Wei Z,Li Y,Huang W,Wang W,Jiang Q,Meng X,Zeng Y,Wang P

更新日期：2018-11-12 00:00:00