Abstract：
:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Farmery JHR,Smith ML,NIHR BioResource - Rare Diseases.,Lynch AGdoi
10.1038/s41598-018-31524-0subject
Has Abstractpub_date
2018-09-03 00:00:00pages
13376issue
1issn
2045-2322pii
10.1038/s41598-018-31524-0journal_volume
8pub_type
已发布勘误abstract：:Direct phenological mismatch caused by climate change can occur in mammals that moult seasonally. Two colour morphs of the weasel Mustela nivalis (M. n.) occur sympatrically in Białowieża Forest (NE Poland) and differ in their winter pelage colour: white in M. n. nivalis and brown in M. n. vulgaris. Due to their small...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26057-5
更新日期：2018-05-24 00:00:00
abstract：:L-R (left and right) symmetry breaking during embryogenesis and the establishment of asymmetric body plan are key issues in developmental biology, but the onset including the handedness-determining gene locus still remains unknown. Using pure dextral (DD) and sinistral (dd) strains of the pond snail Lymnaea stagnalis ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34809
更新日期：2016-10-06 00:00:00
abstract：:Influenza's propensity for antigenic drift and shift, and to elicit predominantly strain specific antibodies (Abs) leaves humanity susceptible to waves of new strains with pandemic potential for which limited or no immunity may exist. Subsequently new clinical interventions are needed. To identify hemagglutinin (HA) e...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22307-8
更新日期：2018-03-12 00:00:00
abstract：:Majority of novel X-ray crystal structures of proteins are currently solved using the anomalous diffraction signal provided by selenium after incorporation of selenomethionine instead of natural methionine by genetic engineering methods. However, selenium can be inserted into protein crystals in the form of selenourea...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37123
更新日期：2016-11-14 00:00:00
abstract：:Sugarcane (Saccharum spp.) is a globally important crop for sugar and bioenergy production. Its highly polyploid, complex genome has hindered progress in understanding its molecular structure. Flow cytometric sorting and analysis has been used in other important crops with large genomes to dissect the genome into comp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-55652-3
更新日期：2019-12-18 00:00:00
abstract：:The bronchoscopy, though usually safe, is occasionally associated with complications, such as pneumonia. However, the use of prophylactic antibiotics is not recommended by the guidelines of the British Thoracic Society. Thus far there are few reports of the risk factors for post-bronchoscopy pneumonia; the purpose of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76998-z
更新日期：2020-11-17 00:00:00
abstract：:Influenza A and B viruses cause seasonal flu epidemics. The M2 protein of influenza B (BM2) is a membrane-embedded tetrameric proton channel that is essential for the viral lifecycle. BM2 is a functional analog of AM2 but shares only 24% sequence identity for the transmembrane (TM) domain. The structure and function o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40217-1
更新日期：2019-03-06 00:00:00
abstract：:Switching magnetizations with femtosecond circularly polarized lasers may have revolutionary impacts on magnetic data storage and relevant applications. Achievements in ferrimagnetic and ferromagnetic materials of various structures strongly imply a general phenomenon of fundamental atom-laser interaction. Rotating an...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41294
更新日期：2017-01-24 00:00:00
abstract：:An increase of nucleolar number and size has made nucleoli essential markers for cytology and tumour development. However, the underlying basis for their structural integrity and abundance remains unclear. Protein phosphatase PPM1D was found to be up-regulated in different carcinomas including breast cancers. Here, we...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33272
更新日期：2016-09-13 00:00:00
abstract：:Low back pain (LBP) is a widespread debilitating disorder of significant socio-economic importance and intervertebral disc (IVD) degeneration has been implicated in its pathogenesis. Despite its high prevalence the underlying causes of LBP and IVD degeneration are not well understood. Recent work in musculoskeletal de...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12666-z
更新日期：2017-10-02 00:00:00
abstract：:High frequency oscillations (HFOs) are bursts of neural activity in the range of 80 Hz or higher, recorded from intracranial electrodes during epileptiform discharges. HFOs are a proposed biomarker of epileptic brain tissue and may also be useful for seizure forecasting. Despite such clinical utility of HFOs, the spat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76138-7
更新日期：2020-11-05 00:00:00
abstract：:Milk microbiota has a great influence on the safety and quality of dairy products. However, few studies have investigated the variations of bacterial composition in raw milk. In this study, raw milk samples were collected in 12 successive months, and their bacterial compositions were determined by 16 S rRNA gene seque...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20862-8
更新日期：2018-02-05 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep25577. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/srep46944
更新日期：2018-02-16 00:00:00
abstract：:We investigated changes in the temporospatial features of hourly precipitation during the warm season over mainland China. The frequency and amount of hourly precipitation displayed latitudinal zonation, especially for light and moderate precipitation, which showed successive downward change over time in northeastern ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22543
更新日期：2016-03-02 00:00:00
abstract：:Ocean acidification and global warming have been shown to significantly affect the physiological performances of marine calcifiers; however, the underlying mechanisms remain poorly understood. In this study, the transcriptome and biomineralization responses of Pinctada fucata to elevated CO2 (pH 7.8 and pH 7.5) and te...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18943
更新日期：2016-01-06 00:00:00
abstract：:Spintronic devices currently rely on magnetic switching or controlled motion of domain walls by an external magnetic field or spin-polarized current. Achieving the same degree of magnetic controllability using an electric field has potential advantages including enhanced functionality and low power consumption. Here w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00258
更新日期：2012-01-01 00:00:00
abstract：:The prediction of infarction volume after stroke onset depends on the shape of the growth dynamics of the infarction. To understand growth patterns that predict lesion volume changes, we studied currently available models described in literature and compared the models with Adaptive Neuro-Fuzzy Inference System [ANFIS...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08044-4
更新日期：2017-08-08 00:00:00
abstract：:Color vision requires the activity of cone photoreceptors to be compared in post-receptoral circuitry. Decades of psychophysical measurements have quantified the nature of these comparative interactions on a coarse scale. How such findings generalize to a cellular scale remains unclear. To answer that question, we qua...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26754-1
更新日期：2018-06-04 00:00:00
abstract：:In spite of much work on topological insulators (TIs), systematic experiments for TI/TI heterostructures remain absent. We grow a high quality heterostructure containing single quintuple layer (QL) of Bi2Se3 on 19 QLs of Bi2Te3 and compare its transport properties with 20 QLs Bi2Se3 and 20 QLs Bi2Te3. All three films ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03060
更新日期：2013-10-28 00:00:00
abstract：:Genes that encode for enzymes that can degrade petroleum hydrocarbons (PHs) are critical for the ability of microorganisms to bioremediate soils contaminated with PHs. Distributions of two petroleum-degrading genes AlkB and Nah in soils collected from three zones of the Dagang Oilfield, Tianjin, China were investigate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11068
更新日期：2015-06-18 00:00:00
abstract：:Childhood obesity is a risk factor for asthma, but the molecular mechanisms linking both remain elusive. Since obesity leads to chronic low-grade inflammation and affects metabolic signaling we hypothesized that postnatal hyperalimentation (pHA) induced by maternal high-fat-diet during lactation leads to early-onset o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24168
更新日期：2016-04-18 00:00:00
abstract：:Lassa virus (LASV) is the causative agent of Lassa fever (LF), an often-fatal hemorrhagic disease. LF is endemic in Nigeria, Sierra Leone and other West African countries. Diagnosis of LASV infection is challenged by the genetic diversity of the virus, which is greatest in Nigeria. The ReLASV Pan-Lassa Antigen Rapid T...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65736-0
更新日期：2020-05-26 00:00:00
abstract：:Ocular graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation (HSCT). Here we compared the diagnostic rates of ocular GVHD, including its severity, prognosis and the agreement, obtained using three grading scales: the National Institutes of Health (NIH) eye score, Japan...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06680
更新日期：2014-10-22 00:00:00
abstract：:Mycobacterium tuberculosis, the etiological agent of the infectious disease tuberculosis, kills approximately 1.5 million people annually, while the spread of multidrug-resistant strains is of great global concern. Thus, continuous efforts to identify new antitubercular drugs as well as novel targets are crucial. Rece...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-21614-4
更新日期：2018-02-16 00:00:00
abstract：:Thymol, as a dietary monoterpene, is a phenol derivative of cymene, which is the major component of the essential oil of Trachyspermum ammi (L.). It shows multiple biological activities: antifungal, antibacterial, antivirus and anti-inflammatory. T. ammi, commonly known as ajowan, belongs to Apiaceae and is an importa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-31618-9
更新日期：2018-09-07 00:00:00
abstract：:Habitat degradation is among the top drivers of the loss of global biodiversity. This problem is particularly acute in coral reef system. Here we investigated whether coral degradation influences predator risk assessment and learning for damselfish. When in a live coral environment, Ambon damselfish were able to learn...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep32542
更新日期：2016-09-09 00:00:00
abstract：:Listeria monocytogenes is well known for having the ability to cross the placental barrier, leading to fetal infections and abortion. However, the mechanisms leading to infectious abortion are poorly understood. In this study, we demonstrate that interferon γ-induced GTPase (IGTP) contributes to the invasion of L. mon...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08195
更新日期：2015-02-03 00:00:00
abstract：:Target-guided synthesis is an approach to drug discovery that allows the target to self-assemble its own binding agents. So far, target-guided synthesis and especially in situ click chemistry have attracted extensive attention and have led to the identification of highly potent inhibitors for proteins. In this study, ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17202
更新日期：2015-11-25 00:00:00
abstract：:Duchenne muscular dystrophy (DMD) is a common and severe X-linked myopathy, characterized by muscle degeneration due to altered or absent dystrophin. DMD has no effective cure, and the underlying molecular mechanisms remain incompletely understood. The aim of this study is to investigate the metabolic changes in DMD u...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81090-1
更新日期：2021-01-21 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-23087-x
更新日期：2018-03-19 00:00:00
