Abstract:
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journal_name
Sci Repjournal_title
Scientific reportsauthors
Randall CJ,van Woesik Rdoi
10.1038/s41598-018-23087-xsubject
Has Abstractpub_date
2018-03-19 00:00:00pages
5049issue
1issn
2045-2322pii
10.1038/s41598-018-23087-xjournal_volume
8pub_type
已发布勘误abstract::Activating transcription factor 4 (ATF4) is constitutively expressed in a variety of tissues, and regulates several pathological features associated with metabolic diseases such as non-alcoholic fatty liver diseases (NAFLD) and obesity. However, the role of ATF4 in animal model systems is poorly understood. To investi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16587-9
更新日期:2017-11-27 00:00:00
abstract::The increasing performance of optical lattice clocks has made them attractive for scientific applications in space and thus has pushed the development of their components including the interrogation lasers of the clock transitions towards being suitable for space, which amongst others requires making them more power e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33973
更新日期:2016-09-26 00:00:00
abstract::Beaver have been referred to as ecosystem engineers because of the large impacts their dam building activities have on the landscape; however, the benefits they may provide to fluvial fish species has been debated. We conducted a watershed-scale experiment to test how increasing beaver dam and colony persistence in a ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28581
更新日期:2016-07-04 00:00:00
abstract::2-hydroxy-1,4 naphthoquinone (lawsone) is widely used and induces environmental pollutions during its production and application. In the present study, a lawsone-degrading bacterium strain, LH-3 was successfully isolated from the activated sludge. Based on the 16S rRNA gene analysis, the strain LH-3 phylogenetically b...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06338-1
更新日期:2017-07-28 00:00:00
abstract::Despite the detailed characterization of the inflammatory and endothelial changes observed in Sickle Cell Disease (SCD), the hierarchical relationship between elements involved in the pathogenesis of this complex disease is yet to be described. Meta-analyses of gene expression studies from public repositories represen...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/srep17822
更新日期:2015-12-09 00:00:00
abstract::We report a daily-updated sequenced/species Tree Of Life (sTOL) as a reference for the increasing number of cellular organisms with their genomes sequenced. The sTOL builds on a likelihood-based weight calibration algorithm to consolidate NCBI taxonomy information in concert with unbiased sampling of molecular charact...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02015
更新日期:2013-01-01 00:00:00
abstract::Immunotherapies demand for predictive biomarkers to avoid unnecessary adverse effects and costs. Analytic morphomics is the technique to use body composition measures as imaging biomarkers for underlying pathophysiology to predict prognosis or outcome to therapy. We investigated different body composition measures to ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46189-6
更新日期:2019-07-05 00:00:00
abstract::Geographic variation in aridity determines environmental productivity patterns, including large-scale variability in pathogens, vectors and associated diseases. If disease risk decreases with increasing aridity and is matched by immune defense, we predict a decrease in innate immune function along a gradient of increa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62806-1
更新日期:2020-04-03 00:00:00
abstract::Oral squamous cell carcinoma (OSCC) is usually preceded by the oral premalignant lesions, mainly oral leukoplakia (OLK) after repeated insults of carcinogens, tobacco. B(a)P and DMBA are key carcinogens in tobacco smoke. In the present study, for the first time we established the cancerous cell line OSCC-BD induced by...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12668
更新日期:2015-08-03 00:00:00
abstract::Quality control of human induced pluripotent stem cells (iPSCs) can be performed by several methods. These methods are usually relatively labor-intensive, difficult to standardize, or they do not facilitate reliable quantification. Here, we describe a biomarker to distinguish between pluripotent and non-pluripotent ce...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08973
更新日期:2015-03-10 00:00:00
abstract::Toward the increasing demands of portable energy storage and electric vehicle applications, the widely used graphite anodes with significant drawbacks become more and more unsuitable. Herein, we report a novel scaffold of hierarchical silicon nanowires-carbon textiles anodes fabricated via a facile method. Further, co...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01622
更新日期:2013-01-01 00:00:00
abstract::There is a global concern about the effects of climate change driven shifts in species phenology on crop pests. Using geographically and temporally extensive data set of moth trap catches and temperatures across the cotton growing states of India, we predicted the phenology of cotton pink bollworm Pectinophora gossypi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80184-6
更新日期:2021-01-11 00:00:00
abstract::Serotonin (5-HT) is an important neurotransmitter and neuromodulator that controls a variety of sensory and motor functions through 5-HT receptors (5-HTRs). The 5-HT4R subfamily is linked to Gs proteins, which activate adenylyl cyclases (ACs), and is involved in many responses in peripheral organs. In this study, the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40247
更新日期:2017-01-06 00:00:00
abstract::The use of entomopathogenic fungi for biocontrol of plant pests is recently receiving an increased interest due to the need of reducing the impact of agricultural practices on the environment. Biocontrol efficacy could be improved by co-inoculation of different microorganisms. However, interactions between the fungal ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12700-0
更新日期:2017-10-12 00:00:00
abstract::Activation of G protein-gated inwardly rectifying potassium (GIRK) channels leads to a hyperpolarization of the neuron's membrane potential, providing an important component of inhibition in the brain. In addition to the canonical G protein-activation pathway, GIRK channels are activated by small molecules but less is...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04681-x
更新日期:2017-07-04 00:00:00
abstract::Nowadays, increasing awareness of environment and fossil fuels protection stimulates intensive research on clean and renewable sources of energy. Production of hydrogen from water through solar-driven splitting reactions is one of the most promising approaches in the field of photoelectrochemistry (PEC). In this work ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29247-3
更新日期:2018-07-18 00:00:00
abstract::Human metapneumovirus (HMPV) is an important viral respiratory pathogen worldwide. Current knowledge regarding the genetic diversity, seasonality and transmission dynamics of HMPV among adults and children living in tropical climate remains limited. HMPV prevailed at 2.2% (n = 86/3,935) among individuals presented wit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27730
更新日期:2016-06-09 00:00:00
abstract::The ratio between the length of second and fourth digits (2D:4D) is a putative biomarker for prenatal testosterone and estrogen exposure. The aim of the study was to examine the association between 2D:4D and women's general and reproductive health. This analysis was conducted within a prospective pregnancy cohort stud...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62599-3
更新日期:2020-04-14 00:00:00
abstract::Hominin dietary specialization is crucial to understanding the evolutionary changes of craniofacial biomechanics and the interaction of food processing methods' effects on teeth. However, the diet-related dental wear processes of the earliest European hominins remain unknown because most of the academic attention has ...
journal_title:Scientific reports
pub_type: 历史文章,杂志文章
doi:10.1038/srep43319
更新日期:2017-02-27 00:00:00
abstract::Design and development of efficient processes for continuous manufacturing of solid dosage oral formulations is of crucial importance for pharmaceutical industry in order to implement the Quality-by-Design paradigm. Supercritical solvent-based manufacturing can be utilized in pharmaceutical processing owing to its inh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80399-7
更新日期:2021-01-13 00:00:00
abstract::Flotation of small solid objects and liquid droplets on water is critical to natural and industrial activities. This paper reports the floating mechanism of liquid marbles, or liquid droplets coated with hydrophobic microparticles. We used X-ray computed tomography (XCT) to acquire cross-sectional images of the floati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21777
更新日期:2016-02-23 00:00:00
abstract::The epidermis of snakes efficiently protects against dehydration and mechanical stress. However, only few proteins of the epidermal barrier to the environment have so far been identified in snakes. Here, we determined the organization of the Epidermal Differentiation Complex (EDC), a cluster of genes encoding protein ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45338
更新日期:2017-03-27 00:00:00
abstract::SR-BI is the main receptor for high density lipoproteins (HDL) and mediates the bidirectional transport of lipids, such as cholesterol and vitamin E, between these particles and cells. During early development, SR-BI is expressed in extraembryonic tissue, specifically in trophoblast giant cells in the parietal yolk sa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05422-w
更新日期:2017-07-12 00:00:00
abstract::The distinguishing of the multiphoton quantum interference effect from the classical one forms one of the most important issues in modern quantum mechanics and experimental quantum optics. For a long time, the two-photon interference (TPI) of correlated photons has been recognized as a pure quantum effect that cannot ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54504-4
更新日期:2019-12-05 00:00:00
abstract::SUMO belongs to the ubiquitin-like family (UbL) of protein modifiers. SUMO is conserved among eukaryotes and is essential for the regulation of processes such as DNA damage repair, transcription, DNA replication and mitosis. UbL modification of proteins occurs via a specific enzymatic cascade formed by the crosstalk b...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41998
更新日期:2017-02-06 00:00:00
abstract::An effective analysis method was developed based on a chemometric tool for the simultaneous quantification of five different post-harvest pesticides (2,4-dichlorophenoxyacetic acid (2,4-D), carbendazim, thiabendazole, iprodione, and prochloraz) in fruits and vegetables. In the modified QuEChERS (quick, easy, cheap, ef...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42489
更新日期:2017-02-22 00:00:00
abstract::During ice-free periods, the Northern Sea Route (NSR) could be an attractive shipping route. The decline in Arctic sea-ice extent, however, could be associated with an increase in the frequency of the causes of severe weather phenomena, and high wind-driven waves and the advection of sea ice could make ship navigation...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16868
更新日期:2015-11-20 00:00:00
abstract::Plastic represents 60-80% of litter in the ocean. Degradation of plastic to small fragments leads to the formation of microplastics (MPs <5 mm) and nanoplastics (NPs <1 µm). One of the most widely used and representative plastics found in the ocean is polystyrene (PS). Among marine organisms, the immune system of biva...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65596-8
更新日期:2020-05-25 00:00:00
abstract::We discuss subwavelength-scale semiconductor metal-optic resonators placed on the metal substrate with various top metal plate sizes. Albeit with large optical losses, addition of metal layers converts a leaky semiconductor nano-block into a highly-confined optical cavity. Optically pumped lasing action is observed wi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31793
更新日期:2016-08-23 00:00:00
abstract::Liquid foams are classified into a dry foam and a wet foam, empirically judging from the liquid fraction or the shape of the gas bubbles. It is known that physical properties such as elasticity and diffusion are different between the dry foam and the wet foam. Nevertheless, definitions of those states have been vague ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37506
更新日期:2016-11-22 00:00:00