Abstract:
:Clinical data from 172 cases of uterine fibroids with different appearances on MRI-T2WI and accepted ultrasound guided high intensity focused ultrasound (USgHIFU) treatment were retrospectively analyzed. This study aimed to evaluate the clinical safety and efficacy of ablating different types of fibroids, classified by T2-weighted magnetic resonance imaging (MRI-T2WI). Based on MRI-T2WI signal intensities, uterine fibroids were classified as three types: hypointensive (52 cases), isointensive (64 cases) and hyperintensive (56 cases). Evaluation parameters including treatment time, ablation efficiency, percentage non-perfused volume, fibroid reduction rate, adverse reactions, symptom severity scores (SSS) and re-intervention rate were assessed from 3 months to 1 year. The percentage non-perfused volume and ablation efficiency of hyperintensive uterine fibroids were lower than those of isointensive and hypointensive uterine fibroids. All fibroids shrunk and the SSS continued to reduce at 3 and 6 months after treatment respectively. At 12-month postoperative assessments, hypointensive fibroids continued to shrink, while the isointensive fibroids enlarged but remained smaller than pre-treatment. The incident rate of postoperative Society of Interventional Radiology B-class (SIRB-class) adverse events showed no significant differences. The re-interventional rate of hyperintensive fibroids was higher than in isointensive and hypointensive groups. USgHIFU ablation of all types of fibroids were safe and effective.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Zhao WP,Zhang J,Han ZY,Yao JP,Zhou X,Liang Pdoi
10.1038/s41598-017-11486-5subject
Has Abstractpub_date
2017-09-07 00:00:00pages
10812issue
1issn
2045-2322pii
10.1038/s41598-017-11486-5journal_volume
7pub_type
杂志文章abstract::It is known that ribosomal RNA (rRNA) synthesis is regulated by cellular energy and proliferation status. In this study, we investigated rRNA gene transcription in response to cytoskeletal stress. Our data revealed that the cell shape constrained by isotropic but not elongated micropatterns in HeLa cells led to a sign...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28685
更新日期:2016-06-28 00:00:00
abstract::The low-temperature heat capacity of (U1-yThy)O2 and 238Pu-doped UO2 samples were determined using hybrid adiabatic relaxation calorimetry. Results of the investigated systems revealed the presence of the magnetic transition specific for UO2 in all three intermediate compositions of the uranium-thorium dioxide (y = 0....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51476-3
更新日期:2019-10-21 00:00:00
abstract::Wave control in the solid state has opened new avenues in modern information technology. Surface-acoustic-wave-based devices are found as mass market products in 100 millions of cellular phones. Spin waves (magnons) would offer a boost in today's data handling and security implementations, i.e., image processing and s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06848
更新日期:2014-10-30 00:00:00
abstract::In this paper, we propose a strategy for the control of mobile chaotic oscillators by adaptively rewiring connections between nearby agents with local information. In contrast to the dominant adaptive control schemes where coupling strength is adjusted continuously according to the states of the oscillators, our metho...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16235-2
更新日期:2017-11-22 00:00:00
abstract::Metabolites detectible in human biofluids are attractive biomarkers for the diagnosis of early Lyme disease (ELD), a vector-borne infectious disease. Urine represents an easily obtained clinical sample that can be applied for diagnostic purposes. However, few studies have explored urine for biomarkers of ELD. In this ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29713-y
更新日期:2018-08-15 00:00:00
abstract::When realising future fusion reactors, their stationary burning must be maintained and the heat flux to the divertor must be reduced. This essentially requires a stationary internal transport barrier (ITB) plasma with a fast control system. However, the time scale for determining the position of the foot point of an I...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56492-x
更新日期:2020-01-08 00:00:00
abstract::(E)-Methyl-N'-nitrobenzylidene-benzenesulfonohydrazide (MNBBSH) compounds were synthesized using a condensation procedure from the derivatives of nitrobenzaldehyde and 4-Methyl-benzenesulfonylhydrazine, which crystallized in ethanol and methanol as well as characterized by FTIR, UV-Vis, 1H-NMR, and 13C-NMR. MNBBSH str...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05703-4
更新日期:2017-07-19 00:00:00
abstract::Metagenomics brings in new discoveries and insights into the uncultured microbial world. One fundamental task in metagenomics analysis is to determine the taxonomy of raw sequence fragments. Modern sequencing technologies produce relatively short fragments and greatly increase the number of fragments, and thus make th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09947-y
更新日期:2017-08-25 00:00:00
abstract::The elastic responsiveness of single cellulose nanofibres is important for advanced analysis of biological tissues and their use in sophisticated functional materials. However, the mechanical responsiveness derived from the twisted structure of cellulose nanofibres (CNFs) has remained unexplored. In this study, finite...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80890-1
更新日期:2021-01-12 00:00:00
abstract::Biosorption is a cost-effective and simple technique for removing heavy metals and rare earth elements from aqueous solution. Here, metals were recovered from aqueous solutions using phosphorylated dry baker's yeast cells. The cells were phosphorylated using cyclo-triphosphate, Na3P3O9. The total P content of the phos...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36306-2
更新日期:2019-01-18 00:00:00
abstract::Measurement of intracranial aneurysm wall motion may refine the current rupture risk estimation. A golden standard for measuring aneurysm pulsation is lacking. The aim is to evaluate magnitudes of aneurysm pulsation as published in current literature. Embase and PubMed were searched for publications containing quantit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81753-z
更新日期:2021-01-26 00:00:00
abstract::Intervertebral disc degeneration is accompanied by a loss of Extra-cellular matrix (ECM) due to an imbalance in anabolic and catabolic pathways. Identifying ECM proteins with anabolic and/or regenerative potential could be the key to developing regenerative therapies. Since human fetal discs grow and develop rapidly, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72859-x
更新日期:2020-09-24 00:00:00
abstract::Protein electrochemistry represents a powerful technique for investigating the function and structure of proteins. Currently available biochemical assays provide limited information related to the conformational state of proteins and high costs. This work provides novel insights into the electrochemical investigation ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53994-6
更新日期:2019-11-22 00:00:00
abstract::In this paper, we used a facile ball milling, microwave radiation and heating treatment method to achieve the surface modification of TiO2 with low g-C3N4 concentration, and a multilayer heterojunction composite with TiO2 as the main part and g-C3N4 as the modification agent was obtained. The obtained materials were a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-42438-w
更新日期:2019-04-11 00:00:00
abstract::Trypanosoma cruzi is the etiological agent of Chagas disease, a neglected and emerging tropical disease, endemic to South America and present in non-endemic regions due to human migration. The MASP multigene family is specific to T. cruzi, accounting for 6% of the parasite's genome and plays a key role in immune evasi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27293
更新日期:2016-06-08 00:00:00
abstract::The role of non-bilayer lipids and non-lamellar lipid phases in biological membranes is an enigmatic problem of membrane biology. Non-bilayer lipids are present in large amounts in all membranes; in energy-converting membranes they constitute about half of their total lipid content-yet their functional state is a bila...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68854-x
更新日期:2020-07-20 00:00:00
abstract::Bio-functionalized nanoparticles with semiconducting/metallic core encapsulated in a bio- or bio-derived materials are promising for applications in biology and especially in cancer diagnostic and healing. In this report, we report a facile, single-step, first-time synthesis and in-situ functionalization strategy for ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18629
更新日期:2015-12-21 00:00:00
abstract::Attention-deficit/hyperactivity disorder is frequently reported in individuals with Down syndrome, with considerable variation in the expression and severity of the symptoms. Despite growing evidence that gestational age predicts later symptoms of attention-deficit/hyperactivity disorder in the euploid population, thi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77392-5
更新日期:2020-11-23 00:00:00
abstract::Inhaled corticosteroids (ICSs) are widely prescribed in chronic obstructive pulmonary disease (COPD). However, little is known about predictors of ICSs therapeutic response. To investigate whether the variation in glucocorticoid-induced transcript 1 (GLCCI1) rs37973 is associated with ICS efficacy. A total of 204 clin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42552
更新日期:2017-02-10 00:00:00
abstract::Macroautophagy, the degradation of cytoplasmic content by lysosomal fusion, is an evolutionary conserved process promoting homeostasis and intracellular defence. Macroautophagy is initiated primarily by a complex containing ULK1 or ULK2 (two paralogs of the yeast Atg1 protein). To understand the differences between UL...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67780-2
更新日期:2020-07-02 00:00:00
abstract::Heating on the microscale using focused lasers gave rise to recent applications, e.g., in biomedicine, biology and microfluidics, especially using gold nanoparticles as efficient nanoabsorbers of light. However, such an approach naturally leads to nonuniform, Gaussian-like temperature distributions due to the diffusiv...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40382-3
更新日期:2019-03-15 00:00:00
abstract::In this study, dye-sensitized solar cells (DSSCs) has been assembled with poly(1-vinylpyrrolidone-co-vinyl acetate) (P(VP-co-VAc)) gel polymer electrolytes (GPEs) which have been incorporated with binary salt and an ionic liquid. The potential of this combination was studied and reported. The binary salt system GPEs w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27630
更新日期:2016-06-08 00:00:00
abstract::Drug discovery efforts against the pathogen Mycobacterium tuberculosis (Mtb) have been advanced through phenotypic screens of extensive compound libraries. Such a screen revealed sulfolane 1 and indoline-5-sulfonamides 2 and 3 as potent inhibitors of mycobacterial growth. Optimization in the sulfolane series led to co...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09642-y
更新日期:2017-08-25 00:00:00
abstract::We investigate temperature smearing effects on the electron-boson spectral density function (I(2)χ(ω)) obtained from optical data using a maximum entropy inversion method. We start with two simple model input I(2)χ(ω), calculate the optical scattering rates at selected temperatures using the model input spectral densi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23647
更新日期:2016-03-31 00:00:00
abstract::We report, for the first time, that the energy of femtosecond optical laser pulses, E, with relativistic intensities I > 10(21) W/cm(2) is efficiently converted to X-ray radiation, which is emitted by "hot" electron component in collision-less processes and heats the solid density plasma periphery. As shown by direct...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13436
更新日期:2015-09-02 00:00:00
abstract::The crystallization characteristics in supercooled liquid Zn during isothermal relaxation were investigated using molecular dynamics simulations by adopting the cluster-type index method (CTIM) and the tracing method. Results showed that the crystallization process undergo three different stages. The size of the criti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31653
更新日期:2016-08-16 00:00:00
abstract::Nilaparvata lugens (Stål) (Hemiptera: Delphacidae) is a major rice pest that harbors an endosymbiont ascomycete fungus, Entomomyces delphacidicola str. NLU (also known as yeast-like symbiont, YLS). Driving by demand of novel population management tactics (e.g. RNAi), the importance of YLS has been studied and revealed...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42206
更新日期:2017-02-13 00:00:00
abstract::The development of microstructure during melting, reactive wetting and solidification of solder pastes on Cu-plated printed circuit boards has been studied by synchrotron radiography. Using Sn-3.0Ag-0.5Cu/Cu and Sn-0.7Cu/Cu as examples, we show that the interfacial Cu6Sn5 layer is present within 0.05 s of wetting, and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40010
更新日期:2017-01-12 00:00:00
abstract::Bee pollination is an indispensable component of global food production and plays a crucial role in sustainable agriculture. The worldwide decline of bee populations, including wild pollinators, poses a threat to this system. However, most studies to date are situated in temperate regions where Apini and Bombini are v...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep32547
更新日期:2016-09-02 00:00:00
abstract::Granule cells at the input layer of the cerebellum comprise over half the neurons in the human brain and are thought to be critical for learning. However, little is known about granule neuron signaling at the population scale during behavior. We used calcium imaging in awake zebrafish during optokinetic behavior to re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15938-w
更新日期:2017-11-24 00:00:00